Search Results - "Malberg, J"

Chronic Antidepressant Treatment Increases Neurogenesis in Adult Rat Hippocampus by Malberg, Jessica E, Eisch, Amelia J, Nestler, Eric J, Duman, Ronald S

“…Recent studies suggest that stress-induced atrophy and loss of hippocampal neurons may contribute to the pathophysiology of depression. The aim of this study…”
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Use of A Public Telephone Hotline to Detect Urban Plague Cases by Malberg, J. A., Pape, W. J., Lezotte, D., Hill, A. E.

“…Summary Current methods for vector‐borne disease surveillance are limited by time and cost. To avoid human infections from emerging zoonotic diseases, it is…”
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Co-administration of MDMA with drugs that protect against MDMA neurotoxicity produces different effects on body temperature in the rat by Malberg, J E, Sabol, K E, Seiden, L S

“…The substituted amphetamine 3,4-methylenedioxymethamphetamine (MDMA) has been shown to be neurotoxic to serotonin (5HT) terminals in the rat, and rat body…”
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Small Changes in Ambient Temperature Cause Large Changes in 3,4-Methylenedioxymethamphetamine (MDMA)-Induced Serotonin Neurotoxicity and Core Body Temperature in the Rat by Malberg, Jessica E, Seiden, Lewis S

“…The amphetamine derivative 3,4-methylenedioxymethamphetamine (MDMA) is a drug of abuse and has been shown to be neurotoxic to 5-HT terminals in many species…”
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Preclinical characterization of WAY‐211612: a dual 5‐HT uptake inhibitor and 5‐HT 1A receptor antagonist and potential novel antidepressant by Beyer, CE, Lin, Q, Platt, B, Malberg, J, Hornby, G, Sullivan, KM, Smith, DL, Lock, T, Mitchell, PJ, Hatzenbuhler, NT, Evrard, DA, Harrison, BL, Magolda, R, Pangalos, MN, Schechter, LE, Rosenzweig‐Lipson, S, Andree, TH

“…Background and purpose:  As a combination of 5‐HT selective reuptake inhibitor (SSRI) with 5‐HT 1A receptor antagonism may yield a rapidly acting…”
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Preclinical characterization of WAY‐211612: a dual 5‐HT uptake inhibitor and 5‐HT1A receptor antagonist and potential novel antidepressant by Beyer, CE, Lin, Q, Platt, B, Malberg, J, Hornby, G, Sullivan, KM, Smith, DL, Lock, T, Mitchell, PJ, Hatzenbuhler, NT, Evrard, DA, Harrison, BL, Magolda, R, Pangalos, MN, Schechter, LE, Rosenzweig‐Lipson, S, Andree, TH

“…Background and purpose:  As a combination of 5‐HT selective reuptake inhibitor (SSRI) with 5‐HT1A receptor antagonism may yield a rapidly acting…”
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Increasing hippocampal neurogenesis: a novel mechanism for antidepressant drugs by Malberg, Jessica E, Schechter, Lee E

“…The birth of new neurons, or neurogenesis, in the hippocampal formation has been demonstrated throughout the lifetime of multiple species including humans. A…”
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Neurotoxicity of methamphetamine and methylenedioxymethamphetamine by Seiden, L S, Lew, R, Malberg, J E

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Neuronal plasticity and survival in mood disorders by Duman, Ronald S, Malberg, Jessica, Nakagawa, Shin, D’Sa, Carrol

“…Studies at the basic and clinical levels demonstrate that neuronal atrophy and cell death occur in response to stress and in the brains of depressed patients…”
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Regulation of Adult Neurogenesis by Antidepressant Treatment by Duman, Ronald S, Nakagawa, Shin, Malberg, Jessica

“…Demonstration of neurogenesis in adult brain represents a major advance in our understanding of the cellular mechanisms underlying neuronal remodeling and…”
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Neural plasticity to stress and antidepressant treatment by Duman, Ronald S, Malberg, Jessica, Thome, Johannes

“…Adaptations at the cellular and molecular levels in response to stress and antidepressant treatment could represent a form of neural plasticity that…”
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Regulation of adult neurogenesis by psychotropic drugs and stress by Duman, R S, Malberg, J, Nakagawa, S

“…Proliferation and maturation of neurons has been demonstrated to occur at a significant rate in discrete regions of adult brain, including the hippocampus and…”
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Administration of fenfluramine at different ambient temperatures produces different core temperature and 5-HT neurotoxicity profiles by Malberg, Jessica E, Seiden, Lewis S

“…This study investigated the effect of two different ambient temperatures on fenfluramine-induced 5-HT neurotoxicity. Fenfluramine (FEN) (12.5 mg/kg×4;…”
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Localization of Phosphorylated cAMP Response Element-Binding Protein in Immature Neurons of Adult Hippocampus by Nakagawa, Shin, Kim, Ji-Eun, Lee, Rena, Chen, Jingshan, Fujioka, Takashi, Malberg, Jessica, Tsuji, Shuichi, Duman, R. S

“…Neurogenesis continues to occur in the adult hippocampus, although many of the newborn cells degenerate 1-2 weeks after birth. The number and survival of…”
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Cell Proliferation in Adult Hippocampus is Decreased by Inescapable Stress: Reversal by Fluoxetine Treatment by MALBERG, Jessica E, DUMAN, Ronald S

“…Adult hippocampal neurogenesis has been demonstrated in several species and is regulated by both environmental and pharmacological stimuli. The present study…”
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Implications of adult hippocampal neurogenesis in antidepressant action by MALBERG, Jessica E

“…In the dentate gyrus of the hippocampus, cell birth and maturation into neurons, or neurogenesis, occur throughout the lifetime of animals and humans. Multiple…”
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Central administration of IGF-I and BDNF leads to long-lasting antidepressant-like effects by Hoshaw, Brian A., Malberg, Jessica E., Lucki, Irwin

“…Drug development research has identified neurotrophic factors as a downstream target of chronic antidepressant treatments. In order to study their…”
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Differential regulation of central BDNF protein levels by antidepressant and non-antidepressant drug treatments by Balu, Darrick T, Hoshaw, Brian A, Malberg, Jessica E, Rosenzweig-Lipson, Sharon, Schechter, Lee E, Lucki, Irwin

“…Abstract Antidepressant treatments have been proposed to produce their therapeutic effects, in part, through increasing neurotrophin levels in the brain. The…”
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Antidepressant action: to the nucleus and beyond by Malberg, Jessica E., Blendy, Julie A.

“…After decades of effort, the field of depression research is far from understanding how antidepressant drugs mediate their clinical effects. The time lag of…”
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Anxiolytic-like activity of oxytocin in male mice : behavioral and autonomic evidence, therapeutic implications by RING, Robert H, MALBERG, Jessica E, POTESTIO, Lisa, JULIA PING, BOIKESS, Steve, BIN LUO, SCHECHTER, Lee E, RIZZO, Stacey, RAHMAN, Zia, ROSENZWEIG-LIPSON, Sharon

“…Oxytocin (OT) acts as a neuromodulator/neurotransmitter within the central nervous system (CNS) and regulates a diverse range of CNS functions. Notably,…”
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