Search Results - "Malawista, S. E."

Lyme disease: recommendations for diagnosis and treatment by Rahn, D W, Malawista, S E

“…The incidence and the endemic range of Lyme disease in the United States have increased steadily since the disease was originally recognized in Lyme,…”
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Exploitation of Interleukin-8-Induced Neutrophil Chemotaxis by the Agent of Human Granulocytic Ehrlichiosis by AKKOYUNLU, Mustafa, MALAWISTA, Stephen E, ANGUITA, Juan, FIKRIG, Erol

“…Classifications Services IAI Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley Reddit…”
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Inhibition of Borrelia burgdorferi-Tick Interactions In Vivo by Outer Surface Protein A Antibody by Pal, Utpal, Montgomery, Ruth R, Lusitani, Denise, Voet, Pierre, Weynants, Vincent, Malawista, Stephen E, Lobet, Yves, Fikrig, Erol

“…Borrelia burgdorferi outer surface protein (Osp) A is preferentially expressed by spirochetes in the Ixodes scapularis gut and facilitates pathogen-vector…”
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Urate crystals stimulate production of tumor necrosis factor alpha from human blood monocytes and synovial cells : cytokine mRNA and protein kinetics, and cellular distribution by DI GIOVINE, F. S, MALAWISTA, S. E, THORNTON, E, DUFF, G. W

“…Crystals of monosodium urate (MSU) provide a dose-dependent stimulus for the production by human blood monocytes of tumor necrosis factor (TNF), a cytokine…”
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Entry of Borrelia burgdorferi into macrophages is end-on and leads to degradation in lysosomes by MONTGOMERY, R. R, MALAWISTA, S. E

“…The Lyme disease spirochete, Borrelia burgdorferi, is ingested rapidly by mouse macrophages in vitro. Spirochetes attach by their ends and become progressively…”
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Target Imbalance: Disparity of Borrelia burgdorferi Genetic Material in Synovial Fluid from Lyme Arthritis Patients by Persing, David H., Rutledge, Barbara J., Rys, Paul N., Podzorski, Diane S., Mitchell, Paul D., ,, Kurt D. Ree, Liu, Bing, Fikrig, Erol, Malawista, Stephen E.

“…Lyme arthritis is a late manifestation of Lyme disease that results in episodic synovial inflammation and swelling. Although this process is thought to be…”
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Resolution of Lyme arthritis, acute or prolonged: a new look by Malawista, S E

“…I have presented a paradigm for the pathogenesis and resolution of Lyme arthritis founded upon the clinical facts that describe its natural history, and…”
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The fate of Borrelia burgdorferi, the agent for Lyme disease, in mouse macrophages. Destruction, survival, recovery by Montgomery, RR, Nathanson, MH, Malawista, SE

“…The macrophage is a known reservoir for a number of infectious agents, and is therefore a likely candidate site for persistence of Borrelia burgdorferi, the…”
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Fate Of Borrelia burgdorferi DNA In Tissues Of Infected Mice After Antibiotic Treatment by Malawista, Stephen E., Barthold, Stephen W., Persing, David H.

“…Persistence of Borrelia burgdorferi DNA in tissues following antibiotic treatment was evaluated in C3H mice inoculated intradermally with 103 B. burgdorferi…”
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Evidence for reactive nitrogen intermediates in killing of staphylococci by human neutrophil cytoplasts : a new microbicidal pathway for polymorphonuclear leukocytes by MALAWISTA, S. E, MONTGOMERY, R. R, VAN BLARICOM, G

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Neurologic abnormalities of Lyme disease: successful treatment with high-dose intravenous penicillin by Steere, A C, Pachner, A R, Malawista, S E

“…Twelve patients were treated with high-dose intravenous penicillin for neurologic abnormalities of Lyme disease. Headache, stiff neck, and radicular pain…”
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Protein kinase C isoforms in human neutrophil cytoplasts by Smallwood, J I, Malawista, S E

“…Granule-poor human neutrophil cytoplasts, prepared without heat or cytochalasin B treatment so as to preserve both motile function and activatable respiratory…”
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Interleukin 1 (IL 1) as a mediator of crystal arthritis. Stimulation of T cell and synovial fibroblast mitogenesis by urate crystal-induced IL 1 by Di Giovine, FS, Malawista, SE, Nuki, G, Duff, GW

“…We reported before that monosodium urate (MSU) crystals were potent stimulators of endogenous pyrogen (EP) production from human and rabbit mononuclear…”
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Detection of Borrelia burgdorferi DNA in museum specimens of Ixodes dammini ticks by Persing, D.H. (Mayo Foundation, Rochester, MN), Telford, S.R. III, Rys, P.N, Dodge, D.E, White, T.J, Malawista, S.E, Spielman, A

“…In order to investigate the potential for Borrelia burgdorferi infection before the recognition of Lyme disease as a clinical entity, the polymerase chain…”
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Lyme arthritis. Spirochetes found in synovial microangiopathic lesions by Johnston, YE, Duray, PH, Steere, AC, Kashgarian, M, Buza, J, Malawista, SE, Askenase, PW

“…In 17 patients with Lyme disease, synovial specimens, obtained by synovectomy or needle biopsy, showed nonspecific villous hypertrophy, synovial cell…”
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Geographic clustering of an outer surface protein A mutant of Borrelia burgdorferi. Possible implications of multiple variants for Lyme disease persistence by Malawista, S. E., Montgomery, R. R., Wang, X.‐M., Fu, L. L., Giles, S. S.

“…DNA sequences encoding full‐length outer surface protein (Osp) A were amplified from four joint fluid samples over 4.5 months from a patient with chronic Lyme…”
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The early clinical manifestations of Lyme disease by Steere, A C, Bartenhagen, N H, Craft, J E, Hutchinson, G J, Newman, J H, Rahn, D W, Sigal, L H, Spieler, P N, Stenn, K S, Malawista, S E

“…Lyme disease, caused by a tick-transmitted spirochete, typically begins with a unique skin lesion, erythema chronicum migrans. Of 314 patients with this skin…”
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Cytoplasts Generate Oxidants but Require Added Neutrophil Granule Constituents for Fungicidal Activity against Candida albicans Hyphae by Stein, David K., Malawista, Stephen E., Van Blaricom, Gretchen, Wysong, Deborah, Diamond, Richard D.

“…Killing of Candida albicans hyphae requires oxidant generation by neutrophils (PMNL), but it is uncertain whether hyphal killing is mediated by PMNL oxidants…”
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A Vaccine Consisting of Recombinant Borrelia burgdorferi Outer-Surface Protein A to Prevent Lyme Disease by Sigal, Leonard H, Zahradnik, John M, Lavin, Philip, Patella, Sondra J, Bryant, Gary, Haselby, Ray, Hilton, Eileen, Kunkel, Mark, Adler-Klein, Debra, Doherty, Terrence, Evans, Janine, Malawista, Stephen E, Molloy, Philip J, Seidner, Adam L, Sabetta, James R, Simon, Henry J, Klempner, Mark S, Mays, John, Marks, Donald

“…Lyme disease is a multisystem inflammatory disease caused by Borrelia burgdorferi, transmitted by the bite of infected ixodes ticks. B. burgdorferi elicits an…”
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Misoprostol stimulates leukocyte cyclic adenosine 3',5' monophosphate production and synergizes with colchicine: novel combination of established drugs may boost anti-inflammatory potential by Smallwood, J I, Malawista, S E

“…Elevation of intracellular cyclic adenosine 3',5' monophosphate (cAMP) inhibits various proinflammatory and immune responses of leukocytes. Among agents known…”
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