Search Results - "Malarikova, Diana"

Complex genetic and histopathological study of 15 patient-derived xenografts of aggressive lymphomas by Jakša, Radek, Karolová, Jana, Svatoň, Michael, Kazantsev, Dmitry, Grajciarová, Martina, Pokorná, Eva, Tonar, Zbyněk, Klánová, Magdalena, Winkowska, Lucie, Maláriková, Diana, Vočková, Petra, Forsterová, Kristina, Renešová, Nicol, Dolníková, Alexandra, Nožičková, Kristýna, Dundr, Pavel, Froňková, Eva, Trněný, Marek, Klener, Pavel

“…Non-Hodgkin lymphomas (NHL) represent the most common hematologic malignancies. Patient-derived xenografts (PDXs) are used for various aspects of translational…”
Get full text

Cyclin dependent kinase 4/6 inhibitor palbociclib synergizes with BCL2 inhibitor venetoclax in experimental models of mantle cell lymphoma without RB1 deletion by Malarikova, Diana, Jorda, Radek, Kupcova, Kristyna, Senavova, Jana, Dolnikova, Alexandra, Pokorna, Eva, Kazantsev, Dmitry, Nozickova, Kristina, Sovilj, Dana, Bellanger, Celine, Chiron, David, Andera, Ladislav, Krystof, Vladimir, Strnad, Miroslav, Helman, Karel, Klanova, Magdalena, Trneny, Marek, Havranek, Ondrej, Klener, Pavel

“…Mantle cell lymphoma (MCL) is a chronically relapsing malignancy with deregulated cell cycle progression. We analyzed efficacy, mode of action, and predictive…”
Get full text

BCL-XL Blockage with A1155463 Significantly Increases Efficacy of Venetoclax in Mantle Cell Lymphoma in Vitro and In Vivo by Dolníková, Alexandra, Kazantsev, Dmitry, Malarikova, Diana, Pokorna, Eva, Sovilj, Dana, Kelemen, Cristina Daniela, Andera, Ladislav, Trněný, Marek, Klener, Pavel

Get full text

Promising preclinical efficacy of intravitreally administered tafasitamab and anti‐Hu CD199 on immunocompetent murine model of primary intraocular lymphoma by Skrlova, Eva, Uherkova, Eva, Klimova, Aneta, Malarikova, Diana, Svozilkova, Petra, Matous, Petr, Herynek, Vit, Kucera, Tomas, Klener, Pavel, Heissigerova, Jarmila

“…Aims/Purpose: This project aimed to evaluate the efficacy of anti‐CD19 monoclonal antibody tafasitamab and experimental chemokine receptor blocker anti‐Hu…”
Get full text

Cyclin-Dependent Kinase 4/6 Inhibitor Palbociclib Synergizes with BH3-Mimetics in Experimental Models of Relapsed/Refractory Mantle Cell Lymphoma by Malarikova, Diana, Jorda, Radek, Dolníková, Alexandra, Havranek, Ondrej, Pokorna, Eva, Kazantsev, Dmitry, Sovilj, Dana, Helman, Karel, Klanova, Magdalena, Andera, Ladislav, Strnad, Miroslav, Chiron, David, Trneny, Marek, Klener, Pavel

Get full text

Sequencing-Based Analysis of Clonal Evolution of 25 Mantle Cell Lymphoma Patients at Diagnosis and after Failure of Standard Immunochemotherapy by Karolova, Jana, Kazantsev, Dmitry, Svaton, Michael, Tušková, Liliana, Forsterova, Kristina, Malarikova, Diana, Benesova, Katerina, Heizer, Tomáš, Dolníková, Alexandra, Klanova, Magdalena, Fronkova, Eva, Trněný, Marek, Klener, Pavel

Get full text

Cyclin-Dependent Kinase 4/6 Inhibitor Palbociclib Synergizes with BCL2 Inhibitor Venetoclax in Experimental Models of Chemotherapy Refractory Mantle Cell Lymphoma by Malarikova, Diana, Jorda, Radek, Dolnikova, Alexandra, Pokorna, Eva, Kazantsev, Dmitry, Havranek, Ondrej, Helman, Karel, Klanova, Magdalena, Strnad, Miroslav, Trneny, Marek, Klener, Pavel

“…Introduction: Mantle cell lymphoma (MCL) is an aggressive subtype of B-cell non-Hodkin lymphomas characterized by cyclin D1 overexpression, and other recurrent…”
Get full text

Experimental model of primary intraocular lymphoma based on BALB/CaNn strain and A20 cells is optimal for investigational research by Skrlova, Eva, Uherkova, Eva, Klimova, Aneta, Malarikova, Diana, Svozilkova, Petra, Matous, Petr, Herynek, Vit, Kucera, Tomas, Klener, Pavel, Heissigerova, Jarmila

Get full text

A high TP53 mutation burden is a strong predictor of primary refractory mantle cell lymphoma by Obr, Ales, Klener, Pavel, Furst, Tomas, Kriegova, Eva, Zemanova, Zuzana, Urbankova, Helena, Jirkuvova, Andrea, Petrackova, Anna, Malarikova, Diana, Forsterova, Kristina, Cudova, Barbora, Sedlarikova, Lenka, Berkova, Adela, Kasalova, Nela, Papajik, Tomas, Trneny, Marek

Get full text

Ibrutinib in mantle cell lymphoma: a real-world retrospective multi-center analysis of 77 patients treated in the Czech Republic by Obr, Ales, Benesova, Katerina, Janikova, Andrea, Mocikova, Heidi, Belada, David, Hruskova, Andrea, Vockova, Petra, Salek, David, Sykorova, Alice, Furst, Tomas, Malarikova, Diana, Papajik, Tomas, Trneny, Marek, Klener, Pavel

“…Ibrutinib revolutionized therapy for relapsed/refractory (R/R) mantle cell lymphoma (MCL). Real-world data on the outcome of unselected patients are still…”
Get full text

Concurrent TP53 and CDKN2A Gene Aberrations in Newly Diagnosed Mantle Cell Lymphoma Correlate with Chemoresistance and Call for Innovative Upfront Therapy by Malarikova, Diana, Berkova, Adela, Obr, Ales, Blahovcova, Petra, Svaton, Michael, Forsterova, Kristina, Kriegova, Eva, Prihodova, Eva, Pavlistova, Lenka, Petrackova, Anna, Zemanova, Zuzana, Trneny, Marek, Klener, Pavel

“…Mantle cell lymphoma (MCL) is a subtype of B-cell lymphoma with a large number of recurrent cytogenetic/molecular aberrations. Approximately 5-10% of patients…”
Get full text

Comparison of two primary intraocular lymphoma experimental murine models by Skrlova, Eva, Uherkova, Eva, Malarikova, Diana, Klimova, Aneta, Svozilkova, Petra, Kesa, Peter, Matous, Petr, Herynek, Vit, Kucera, Tomas, Klener, Pavel, Heissigerova, Jarmila

“…Purpose: The research on experimental models of primary intraocular lymphoma (PIOL) helps to elucidate pathophysiology of the disease and to find new…”
Get full text

Complex genetic and histopathological study of 15 patient-derived xenografts of aggressive lymphomas by Jakša, Radek, Karolová, Jana, Svatoň, Michael, Kazantsev, Dmitry, Grajciarová, Martina, Pokorná, Eva, Tonar, Zbyněk, Klánová, Magdalena, Winkowska, Lucie, Maláriková, Diana, Vočková, Petra, Forsterová, Kristina, Renešová, Nicol, Dolníková, Alexandra, Nožičková, Kristýna, Dundr, Pavel, Froňková, Eva, Trněný, Marek, Klener, Pavel

“…Non-Hodgkin lymphomas (NHL) represent the most common hematologic malignancies. Patient-derived xenografts (PDXs) are used for various aspects of translational…”
Get full text