Search Results - "Malakondaiah, Golla China"
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Diastereoselective synthesis of a core fragment of ritonavir and lopinavir
Published in Tetrahedron letters (21-12-2011)“…A novel approach to the synthesis of Boc-core, a key starting material for ritonavir and lopinavir involving an unprecedented diastereoselective nitroaldol…”
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Effect of Solvent on Stereoselectivity in Pd/C (Type 39K)-Catalyzed Hydrogenation of Methyl 3-Oxo-4-aza-5-androstene-17-carboxylate, A Key Intermediate for Finasteride and Dutasteride
Published in Organic process research & development (01-09-2007)“…Solvent effects were studied in the stereoselective hydrogenation of methyl 3-oxo-4-aza-5-androstene-17-carboxylate (7) using re-activated Pd/C (type 39K) as a…”
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3
Synthesis of Zolmitriptan and Related Substances
Published in Synthetic communications (17-12-2013)“…Efficient and cost-effective synthesis of Zolmitriptan 1 employing Japp-Klingemann reaction and a new robust purification strategy is described…”
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Synthesis and Process Optimization of Amtolmetin: An Antiinflammatory Agent
Published in Organic process research & development (19-03-2010)“…Efforts toward the synthesis and process optimization of amtolmetin guacil 1 are described. High-yielding electrophilic substitution followed by Wolf−Kishner…”
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5
Scalable Process for the Premix of Esomeprazole
Published in Organic process research & development (20-11-2009)“…An efficient, scalable process for the premix of unstable esomeprazole base is described that allows accessibility to the stable amorphous form of esomeprazole…”
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Expeditious Synthesis of Ramipril: An Angiotensin Converting Enzyme (ACE) Inhibitor
Published in Synthetic communications (01-05-2008)“…We document an efficient and cost-effective synthesis of ramipril 1 utilizing (i) an environmentally benign process for the esterification of racemic…”
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An Investigation on Key Parameters That Influence the Resolution of Omeprazole Sodium
Published in Organic process research & development (01-01-2008)“…In this document are highlighted systematic studies on factors such as water content, temperature, solvent, and mole ratio of the resolving agents that…”
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