Search Results - "Malabed, Raymond"
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Sterol-recognition ability and membrane-disrupting activity of Ornithogalum saponin OSW-1 and usual 3-O-glycosyl saponins
Published in Biochimica et biophysica acta. Biomembranes (01-12-2017)“…OSW-1 is a structurally unique steroidal saponin isolated from the bulbs of Ornithogalum saundersiae, and has exhibited highly potent and selective…”
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Structures of the Largest Amphidinol Homologues from the Dinoflagellate Amphidinium carterae and Structure–Activity Relationships
Published in Journal of natural products (Washington, D.C.) (22-11-2017)“…Amphidinols are polyketide metabolites produced by marine dinoflagellates and are chiefly composed of a long linear chain with polyol groups and polyolefins…”
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Antioxidant, cytotoxic, and anti-venom activity of Alstonia parvifolia Merr. Bark
Published in Asian Pacific journal of tropical biomedicine (01-10-2021)“…Objective: To evaluate antioxidant, cytotoxic, and anti-venom capacity of crude bark extracts of Alstonia parvifolia Merr. Methods: Gas chromatography-mass…”
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Antioxidant, Cytotoxicity, and Antiophidian Potential of Alstonia macrophylla Bark
Published in ACS omega (31-05-2019)“…The objective of this research was to find the possible pharmacognosy of the bark of the Philippine Alstonia macrophylla Wall. ex G.Don (AM). Gas…”
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Interactions of OSW‑1 with Lipid Bilayers in Comparison with Digitonin and Soyasaponin
Published in Langmuir (07-04-2020)“…OSW-1, a unique steroidal saponin isolated from the bulbs of Ornithogalum saundersiae, has potent cell-growth inhibition activity. In this study, we conducted…”
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β-Glucosylation of cholesterol reduces sterol-sphingomyelin interactions
Published in Biochimica et biophysica acta. Biomembranes (01-02-2021)“…Cholesteryl-β-D-glucoside (ChoGlc) is a mammalian glycolipid that is expressed in brain tissue. The effects of glucosylation on the ordering and lipid…”
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Theonellamide A, a marine-sponge-derived bicyclic peptide, binds to cholesterol in aqueous DMSO: Solution NMR-based analysis of peptide-sterol interactions using hydroxylated sterol
Published in Biochimica et biophysica acta. Biomembranes (01-01-2019)“…Theonellamides (TNMs) are antifungal and cytotoxic bicyclic dodecapeptides isolated from the marine sponge Theonella sp. The inclusion of cholesterol (Chol) or…”
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