Search Results - "Malý, Petr"

Current therapeutic targets and multifaceted physiological impacts of caffeine by Song, Xinjie, Kirtipal, Nikhil, Lee, Sunjae, Malý, Petr, Bharadwaj, Shiv

“…Caffeine, which shares consubstantial structural similarity with purine adenosine, has been demonstrated as a nonselective adenosine receptor antagonist for…”
Get full text

Current understanding on TREM-2 molecular biology and physiopathological functions by Bharadwaj, Shiv, Groza, Yaroslava, Mierzwicka, Joanna M., Malý, Petr

“…[Display omitted] •TREM-2 modulates both innate and adaptive immunity via pleotropic pathways.•TREM-2/DAP12/SYK-mediated pathways determines the fates of…”
Get full text

High harmonic generation enhanced by magnetic dipole resonance in an amorphous silicon metasurface by Peterka, Pavel, Šobáň, Zbyněk, Trojánek, František, Malý, Petr, Kozák, Martin

“…We report on the enhancement of high harmonic generation (HHG) yield in a metasurface consisting of amorphous silicon disks in a periodic array on an insulator…”
Get full text

Secretion and surface display of binders of IL-23/IL-17 cytokines and their receptors in Lactococcus lactis as a therapeutic approach against inflammation by Plavec, Tina Vida, Klemenčič, Kaja, Kuchař, Milan, Malý, Petr, Berlec, Aleš

“…The cytokine IL-23 activates the IL-23 receptor (IL-23R) and stimulates the differentiation of naïve T helper (Th) cells into a Th17 cell population that…”
Get full text

Understanding on the possible routes for SARS CoV-2 invasion via ACE2 in the host linked with multiple organs damage by Kirtipal, Nikhil, Kumar, Sanjay, Dubey, Sumit Kumar, Dwivedi, Vivek Dhar, Gireesh Babu, K., Malý, Petr, Bharadwaj, Shiv

“…Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), accountable for causing the coronavirus diseases 2019 (COVID-19), is already declared as a…”
Get full text

Neutrophil Extracellular Traps and Thrombolysis Resistance: New Insights for Targeting Therapies by Mengozzi, Luca, Barison, Ilaria, Malý, Martin, Lorenzoni, Giulia, Fedrigo, Marny, Castellani, Chiara, Gregori, Dario, Malý, Petr, Matěj, Radoslav, Toušek, Petr, Widimský, Petr, Angelini, Annalisa

“…Thrombosis is linked to neutrophil release of neutrophil extracellular traps (NETs). NETs are proposed as a mechanism of resistance to thrombolysis. This study…”
Get full text

Viral informatics: bioinformatics-based solution for managing viral infections by Kumar, Sanjay, Kumar, Geethu S, Maitra, Subhrangsu Sundar, Malý, Petr, Bharadwaj, Shiv, Sharma, Pradeep, Dwivedi, Vivek Dhar

“…Abstract Several new viral infections have emerged in the human population and establishing as global pandemics. With advancements in translation research, the…”
Get full text

Hot-carrier transport in diamond controlled by femtosecond laser pulses by Kozak, Martin, Trojanek, Frantisek, Maly, Petr

“…A laser-induced transient grating technique with femtosecond temporal resolution was used for the study of hot-carrier diffusion and anisotropy of an ambipolar…”
Get full text

Cell immunocapture microfluidic chip based on high-affinity recombinant protein binders by Smejkal, Jiří, Malý, Petr, Kuchař, Milan, Panova, Natalya, Semerádtová, Alena, Aubrecht, Petr, Štofik, Marcel, Malý, Jan

“…Cell immunocapture microfluidic devices represent a rapidly developing field with many potential applications in medical diagnostics. The core of such approach…”
Get full text

Photoluminescence dynamics and quantum yield of intrinsically conductive ZnO from atomic layer deposition by Beh, Holger, Hiller, Daniel, Salava, Jan, Trojánek, František, Zacharias, Margit, Malý, Petr, Valenta, Jan

“…Zinc oxide (ZnO) thin films deposited by atomic layer deposition (ALD) and a (0001)-oriented bulk-ZnO single-crystal are compared by ultrafast time-resolved…”
Get full text

Engineering PD-1-targeted small protein variants for in vitro diagnostics and in vivo PET imaging by Mierzwicka, Joanna Maria, Petroková, Hana, Kafková, Leona Rašková, Kosztyu, Petr, Černý, Jiří, Kuchař, Milan, Petřík, Miloš, Bendová, Kateřina, Krasulová, Kristýna, Groza, Yaroslava, Vaňková, Lucie, Bharadwaj, Shiv, Panova, Natalya, Křupka, Michal, Škarda, Jozef, Raška, Milan, Malý, Petr

“…Programmed cell death 1 (PD-1) belongs to immune checkpoint proteins ensuring negative regulation of the immune response. In non-small cell lung cancer…”
Get full text

p19-Targeting ILP Protein Blockers of IL-23/Th-17 Pro-Inflammatory Axis Displayed on Engineered Bacteria of Food Origin by Škrlec, Katja, Zadravec, Petra, Hlavničková, Marie, Kuchař, Milan, Vaňková, Lucie, Petroková, Hana, Křížová, Lucie, Černý, Jiří, Berlec, Aleš, Malý, Petr

“…IL-23-mediated Th-17 cell activation and stimulation of IL-17-driven pro-inflammatory axis has been associated with autoimmunity disorders such as Inflammatory…”
Get full text

Temperature and density dependence of exciton dynamics in IIa diamond: Experimental and theoretical study by Kozak, Martin, Trojanek, Frantisek, Maly, Petr

“…We studied dependence of time‐resolved and time‐integrated photoluminescence of free excitons in IIa type monocrystalline diamond on sample temperature and…”
Get full text

Human IL-22 receptor-targeted small protein antagonist suppress murine DSS-induced colitis by Kuchař, Milan, Sloupenská, Kristýna, Rašková Kafková, Leona, Groza, Yaroslava, Škarda, Jozef, Kosztyu, Petr, Hlavničková, Marie, Mierzwicka, Joanna M, Osička, Radim, Petroková, Hana, Walimbwa, Stephen I, Bharadwaj, Shiv, Černý, Jiří, Raška, Milan, Malý, Petr

“…Human interleukin-22 (IL-22) is known as a "dual function" cytokine that acts as a master regulator to maintain homeostasis, structural integrity of the…”
Get full text

Momentum-dependent intraband high harmonic generation in a photodoped indirect semiconductor by Suthar, Pawan, Trojánek, František, Malý, Petr, Derrien, Thibault J.-Y., Kozák, Martin

“…Nonlinear optical response of solid-state materials exposed to strong non-resonant light fields leads to the generation of harmonic frequencies as a…”
Get full text

Development of Recombinant Lactococcus lactis Displaying Albumin-Binding Domain Variants against Shiga Toxin 1 B Subunit by Zadravec, Petra, Marečková, Lucie, Petroková, Hana, Hodnik, Vesna, Perišić Nanut, Milica, Anderluh, Gregor, Štrukelj, Borut, Malý, Petr, Berlec, Aleš

“…Infections with shiga toxin-producing bacteria, like enterohemorrhagic Escherichia coli and Shigella dysenteriae, represent a serious medical problem. No…”
Get full text

Optical study of carrier diffusion and recombination in CVD diamond by Kozak, Martin, Trojanek, Frantisek, Maly, Petr

“…We report on the measurements of nonequilibrium carrier dynamics in monocrystalline diamond prepared by the chemical vapor deposition (CVD) technique…”
Get full text

Computational Investigations on the Natural Small Molecule as an Inhibitor of Programmed Death Ligand 1 for Cancer Immunotherapy by Kumar, Geethu S, Moustafa, Mahmoud, Sahoo, Amaresh Kumar, Malý, Petr, Bharadwaj, Shiv

“…Several therapeutic monoclonal antibodies approved by the FDA are available against the PD-1/PD-L1 (programmed death 1/programmed death ligand 1) immune…”
Get full text

Small protein blockers of human IL-6 receptor alpha inhibit proliferation and migration of cancer cells by Groza, Yaroslava, Lacina, Lukáš, Kuchař, Milan, Rašková Kafková, Leona, Zachová, Kateřina, Janoušková, Olga, Osička, Radim, Černý, Jiří, Petroková, Hana, Mierzwicka, Joanna Maria, Panova, Natalya, Kosztyu, Petr, Sloupenská, Kristýna, Malý, Jan, Škarda, Jozef, Raška, Milan, Smetana, Jr, Karel, Malý, Petr

“…Interleukin-6 (IL-6) is a multifunctional cytokine that controls the immune response, and its role has been described in the development of autoimmune…”
Get full text

Myomedin replicas of gp120 V3 loop glycan epitopes recognized by PGT121 and PGT126 antibodies as non-cognate antigens for stimulation of HIV-1 broadly neutralizing antibodies by Daniel Lišková, Veronika, Kosztyu, Petr, Kuchař, Milan, Černý, Jiří, Bharadwaj, Shiv, Petroková, Hana, Vroblová, Eliška, Křupka, Michal, Malý, Michal, Zosinčuková, Tereza, Šulc, Josef, Rašková Kafková, Leona, Raška, Milan, Malý, Petr

“…Imprinting broadly neutralizing antibody (bNAb) paratopes by shape complementary protein mimotopes represents a potential alternative for developing vaccine…”
Get full text