Search Results - "Malá, M"
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1
Simultaneous Bilateral Femoral Osteotomies in Neurogenic Hip Instability: a Feasibility Study
Published in Acta chirurgiae orthopaedicae et traumatologiae Čechoslovaca (15-04-2021)“…PURPOSE OF THE STUDY The study aimed to evaluate the intraoperative and early postoperative response to simultaneous bilateral femoral osteotomy usually…”
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2
Hyperpolarization-Activated Cyclic Nucleotide-Gated Channels as Drug Targets for Neurological Disorders
Published in Annual review of pharmacology and toxicology (06-01-2020)“…The hyperpolarization-activated cyclic nucleotide-gated (HCN) channels are voltage-gated ion channels that critically modulate neuronal activity. Four HCN…”
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3
Cortical HCN channels: function, trafficking and plasticity
Published in The Journal of physiology (01-07-2014)“…The hyperpolarization‐activated cyclic nucleotide‐gated (HCN) channels belong to the superfamily of voltage‐gated potassium ion channels. They are, however,…”
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4
Clostridium difficile infection and colonisation in children under 3 years of age: prospective comparative study
Published in Epidemiologie, mikrobiologie, imunologie (2019)“…Despite an increasing trend in Clostridium difficile infections (CDI) and high C. difficile colonization rate especially among younger children, infants remain…”
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5
A new HCN1 channelopathy: implications for epilepsy
Published in Brain (London, England : 1878) (17-08-2021)“…This scientific commentary refers to ‘Cation leak underlies neuronal excitability in an HCN1 developmental and epileptic encephalopathy’ by Bleakley et al…”
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6
Cholinergic afferent stimulation induces axonal function plasticity in adult hippocampal granule cells
Published in Neuron (Cambridge, Mass.) (21-01-2015)“…Acetylcholine critically influences hippocampal-dependent learning. Cholinergic fibers innervate hippocampal neuron axons, dendrites, and somata. The effects…”
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Clinical and microbiological characteristics of Clostridium difficile infection in children hospitalized at the Departement of Paediatric Infectious Diseases in Brno between 2013 and 2017
Published in Epidemiologie, mikrobiologie, imunologie (2019)“…Clostridium difficile (C. difficile) plays a minor but important role in paediatrics. The aims of this study were to objectivise data, to show their…”
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8
Pore structure evolution in andesite rocks induced by freeze–thaw cycles examined by non-destructive methods
Published in Scientific reports (19-05-2022)“…In this paper, we compare the values of petrophysical properties before and after 100 freeze–thaw (F–T) cycles, as well as recorded length change behaviour and…”
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9
Loss of Dendritic HCN1 Subunits Enhances Cortical Excitability and Epileptogenesis
Published in The Journal of neuroscience (02-09-2009)“…Hyperpolarization-activated cation nonselective 1 (HCN1) plasticity in entorhinal cortical (EC) and hippocampal pyramidal cell dendrites is a salient feature…”
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10
Functional significance of axonal Kv7 channels in hippocampal pyramidal neurons
Published in Proceedings of the National Academy of Sciences - PNAS (03-06-2008)“…Members of the Kv7 family (Kv7.2-Kv7.5) generate a subthreshold K⁺ current, the M- current. This regulates the excitability of many peripheral and central…”
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11
T-type Ca2+ and persistent Na+ currents synergistically elevate ventral, not dorsal, entorhinal cortical stellate cell excitability
Published in Cell reports (Cambridge) (25-07-2023)“…Dorsal and ventral medial entorhinal cortex (mEC) regions have distinct neural network firing patterns to differentially support functions such as spatial…”
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12
Deterioration of volcanic tuffs from rock dwellings in Brhlovce (Slovakia) induced by freeze-thaw cycling studied by non-destructive tests and µCT visualization
Published in Bulletin of engineering geology and the environment (01-05-2024)“…The aim of this paper is to evaluate the effect of freeze-thaw-induced weathering of volcanic tuffs from the rock dwellings in the village of Brhlovce…”
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13
Presynaptic HCN1 channels regulate CaV3.2 activity and neurotransmission at select cortical synapses
Published in Nature neuroscience (01-04-2011)“…The authors find that hyperpolarization-activated cyclic nucleotide–gated 1 (HCN1) channel subunits are localized to the active zone of asymmetric synaptic…”
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14
HCN1 channels: a new therapeutic target for depressive disorders?
Published in Science signaling (02-10-2012)“…The hyperpolarization-activated cyclic nucleotide-gated channels are cation channels that are activated by hyperpolarizing potentials. These channels are…”
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15
Dendritic ion channel trafficking and plasticity
Published in Trends in neurosciences (Regular ed.) (01-07-2010)“…Dendritic ion channels are essential for the regulation of intrinsic excitability as well as modulating the shape and integration of synaptic signals. Changes…”
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16
Microstructural and mechanical characterization of various modified 7XXX series spray formed alloys
Published in Materials characterization (01-01-2008)“…Microstructural analysis was conducted on the second phase constituent particles in various modified 7XXX series alloys produced by spray forming. High…”
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17
HCN1 channels reduce the rate of exocytosis from a subset of cortical synaptic terminals
Published in Scientific reports (10-01-2017)“…The hyperpolarization-activated cyclic nucleotide-gated (HCN1) channels are predominantly located in pyramidal cell dendrites within the cortex. Recent…”
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18
HCN and KV7 (M-) channels as targets for epilepsy treatment
Published in Neuropharmacology (01-06-2013)“…Voltage-gated ion channels are important determinants of cellular excitability. The Hyperpolarization-activated Cyclic Nucleotide-gated (HCN) and KV7 (M-)…”
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19
Differential effects of Kv7 (M‐) channels on synaptic integration in distinct subcellular compartments of rat hippocampal pyramidal neurons
Published in The Journal of physiology (15-12-2011)“…Non‐technical summary Ion channels are pores that allow the exchange of molecules across cell membranes. In nerve cells (neurons) of the hippocampus (a brain…”
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20
Slow strain rate testing and stress corrosion cracking of ultra-fine grained and conventional Al–Mg alloy
Published in Materials science & engineering. A, Structural materials : properties, microstructure and processing (01-12-2014)“…Stress corrosion cracking susceptibility was investigated for an ultra-fine grained (UFG) Al–7.5Mg alloy and a conventional 5083 H111 alloy in natural seawater…”
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