Search Results - "Makynen, A"

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  1. 1

    Validation of Questionnaires in Screening for Restorative Treatment Need among 15-, 21-, and 40-year olds by Kamppi, Antti, Paananen, A, Laajala, A, Karki, S, Kukkola, K, Molkoselka, E, Makynen, A, Laitala, M.L, Päkkilä, J, Anttonen, Vuokko, Tanner, Tarja

    Published in Dental hypotheses (01-01-2022)
    “…Introduction: This cross-sectional study aims to investigate the association between three age-specific questionnaires in three age groups and restorative…”
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    Propiconazole inhibits steroidogenesis and reproduction in the fathead minnow (Pimephales promelas) by Skolness, Sarah Y, Blanksma, Chad A, Cavallin, Jenna E, Churchill, Jessica J, Durhan, Elizabeth J, Jensen, Kathleen M, Johnson, Rodney D, Kahl, Michael D, Makynen, Elizabeth A, Villeneuve, Daniel L, Ankley, Gerald T

    Published in Toxicological sciences (01-04-2013)
    “…Conazoles are designed to inhibit cytochrome P450 (CYP) 14α-demethylase, an enzyme key to fungal cell wall formation. In vertebrates, conazoles may inhibit…”
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    Evaluation of the Aromatase Inhibitor Fadrozole in a Short-Term Reproduction Assay with the Fathead Minnow (Pimephales promelas) by Ankley, Gerald T., Kahl, Michael D., Jensen, Kathleen M., Hornung, Michael W., Korte, Joseph J., Makynen, Elizabeth A., Leino, Richard L.

    Published in Toxicological sciences (01-05-2002)
    “…Cytochrome P450 aromatase (CYP19) is a key enzyme in vertebrate steroidogenesis, catalyzing the conversion of C19 androgens to C18 estrogens such as…”
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  5. 5

    Identification of metabolites of trenbolone acetate in androgenic runoff from a beef feedlot by Durhan, Elizabeth J, Lambright, Christy S, Makynen, Elizabeth A, Lazorchak, James, Hartig, Phillip C, Wilson, Vickie S, Gray, L Earl, Ankley, Gerald T

    Published in Environmental health perspectives (01-04-2006)
    “…Little is known concerning the potential ecological effects of hormonally active substances associated with discharges from animal feeding operations…”
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    Effects of gemfibrozil on lipid metabolism, steroidogenesis, and reproduction in the fathead minnow (Pimephales promelas) by Skolness, Sarah Y., Durhan, Elizabeth J., Jensen, Kathleen M., Kahl, Michael D., Makynen, Elizabeth A., Villeneuve, Daniel L., Ankley, Gerald T.

    Published in Environmental toxicology and chemistry (01-11-2012)
    “…Fibrates are a class of pharmaceuticals that indirectly modulate cholesterol biosynthesis through effects on peroxisome proliferator‐activated receptors…”
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  8. 8

    Description and evaluation of a short-term reproduction test with the fathead minnow (Pimephales promelas) by Ankley, Gerald T., Jensen, Kathleen M., Kahl, Michael D., Korte, Joseph J., Makynen, Elizabeth A.

    Published in Environmental toxicology and chemistry (01-06-2001)
    “…Due to the time and expense associated with full life‐cycle testing, most current toxicity tests with fish do not explicitly consider reproductive output as an…”
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    Ketoconazole in the fathead minnow (Pimephales promelas): Reproductive toxicity and biological compensation by Ankley, Gerald T., Jensen, Kathleen M., Kahl, Michael D., Makynen, Elizabeth A., Blake, Lindsey S., Greene, Katie J., Johnson, Rodney D., Villeneuve, Daniel L.

    Published in Environmental toxicology and chemistry (01-06-2007)
    “…Ketoconazole (KTC) is a model pharmaceutical representing imidazole and triazole pesticides, which inhibit fungal growth through blocking a cytochrome P450…”
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    Dynamic Nature of Alterations in the Endocrine System of Fathead Minnows Exposed to the Fungicide Prochloraz by Ankley, Gerald T., Bencic, David C., Cavallin, Jenna E., Jensen, Kathleen M., Kahl, Michael D., Makynen, Elizabeth A., Martinović, Dalma, Mueller, Nathaniel D., Wehmas, Leah C., Villeneuve, Daniel L.

    Published in Toxicological sciences (01-12-2009)
    “…The vertebrate hypothalamic-pituitary-gonadal (HPG) axis is controlled through various feedback mechanisms that maintain a dynamic homeostasis in the face of…”
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  12. 12

    Effects of the Feedlot Contaminant 17α-Trenbolone on Reproductive Endocrinology of the Fathead Minnow by Jensen, Kathleen M, Makynen, Elizabeth A, Kahl, Michael D, Ankley, Gerald T

    Published in Environmental science & technology (01-05-2006)
    “…Trenbolone acetate is a growth promoter widely used for beef production in the U.S. Two biologically active metabolites of the acetate, 17β- and…”
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  13. 13

    Direct Effects, Compensation, and Recovery in Female Fathead Minnows Exposed to a Model Aromatase Inhibitor by Villeneuve, Daniel L., Mueller, Nathaniel D., Martinović, Dalma, Makynen, Elizabeth A., Kahl, Michael D., Jensen, Kathleen M., Durhan, Elizabeth J., Cavallin, Jenna E., Bencic, David, Ankley, Gerald T.

    Published in Environmental health perspectives (01-04-2009)
    “…Background: Several chemicals in the environment have the potential to inhibit aromatase, an enzyme critical to estrogen synthesis. Objectives: The objective…”
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    REPRODUCTIVE TOXICITY OF VINCLOZOLIN IN THE FATHEAD MINNOW: CONFIRMING AN ANTI-ANDROGENIC MODE OF ACTION by Martinovic, D, Blake, L.S, Durhan, E.J, Greene, K.J, Kahl, M.D, Jensen, K.M, Makynen, E.A, Villeneuve, D.L, Ankley, G.T

    Published in Environmental toxicology and chemistry (01-02-2008)
    “…The objective of the present study was to characterize responses of the reproductive endocrine system of the fathead minnow (Pimephales promelas) to the…”
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    Impacts of an Anti-Androgen and an Androgen/Anti-Androgen Mixture on the Metabolite Profile of Male Fathead Minnow Urine by Collette, Timothy W, Teng, Quincy, Jensen, Kathleen M, Kahl, Michael D, Makynen, Elizabeth A, Durhan, Elizabeth J, Villeneuve, Daniel L, Martinović-Weigelt, Dalma, Ankley, Gerald T, Ekman, Drew R

    Published in Environmental science & technology (01-09-2010)
    “…Male and female fathead minnows (Pimephales promelas, FHM) were exposed via water to 20 or 200 μg/L of cyproterone acetate (CA), a model androgen receptor (AR)…”
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  17. 17

    Comparison of fathead minnow ovary explant and H295R cell-based steroidogenesis assays for identifying endocrine-active chemicals by Villeneuve, Daniel L., Ankley, Gerald T., Makynen, Elizabeth A., Blake, Lindsey S., Greene, Katie J., Higley, Eric B., Newsted, John L., Giesy, John P., Hecker, Markus

    Published in Ecotoxicology and environmental safety (01-09-2007)
    “…An in vitro steroidogenesis assay using H295R human adenocarcinoma cells has been suggested as a possible alternative to gonad explant assays for use as a Tier…”
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    Use of chemical mixtures to differentiate mechanisms of endocrine action in a small fish model by Ankley, Gerald T., Jensen, Kathleen M., Kahl, Michael D., Durhan, Elizabeth J., Makynen, Elizabeth A., Cavallin, Jenna E., Martinović, Dalma, Wehmas, Leah C., Mueller, Nathaniel D., Villeneuve, Daniel L.

    Published in Aquatic toxicology (01-09-2010)
    “…Various assays with adult fish have been developed to identify potential endocrine-disrupting chemicals (EDCs) which may cause toxicity via alterations in the…”
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    Characterization of responses to the antiandrogen flutamide in a short-term reproduction assay with the fathead minnow by Jensen, Kathleen M., Kahl, Michael D., Makynen, Elizabeth A., Korte, Joseph J., Leino, Richard L., Butterworth, Brian C., Ankley, Gerald T.

    Published in Aquatic toxicology (18-11-2004)
    “…A short-term reproduction assay with the fathead minnow ( Pimephales promelas) has been developed to detect chemicals with the potential to disrupt…”
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    Teaching and Evaluation Materials Utilizing Multiple Representations in Mechanics by Savinainen, A, Nieminen, P, Makynen, A, Viiri, J

    Published in Physics education (01-05-2013)
    “…In this paper, we present materials and teaching ideas utilizing multiple representations in the contexts of kinematics and the force concept. These ideas and…”
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