Search Results - "Makusky, Anthony J"
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Composition of the Synaptic PSD-95 Complex
Published in Molecular & cellular proteomics (01-10-2007)“…Postsynaptic density protein 95 (PSD-95), a specialized scaffold protein with multiple protein interaction domains, forms the backbone of an extensive…”
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Journal Article -
2
The human serum proteome: Display of nearly 3700 chromatographically separated protein spots on two-dimensional electrophoresis gels and identification of 325 distinct proteins
Published in Proteomics (Weinheim) (01-07-2003)“…Plasma, the soluble component of the human blood, is believed to harbor thousands of distinct proteins, which originate from a variety of cells and tissues…”
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Journal Article -
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Alterations in the rat serum proteome during liver injury from acetaminophen exposure
Published in The Journal of pharmacology and experimental therapeutics (01-08-2006)“…Changes in the serum proteome were identified during early, fulminant, and recovery phases of liver injury from acetaminophen in the rat. Male F344 rats…”
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Journal Article -
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Characterization of the human urinary proteome: A method for high-resolution display of urinary proteins on two-dimensional electrophoresis gels with a yield of nearly 1400 distinct protein spots
Published in Proteomics (Weinheim) (01-04-2004)“…The abundance profile of the human urinary proteome is known to change as a result of diseases or drug toxicities, particularly of those affecting the kidney…”
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Journal Article -
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A Coordinated Proteomic Approach for Identifying Proteins that Interact with the E. coli Ribosomal Protein S12
Published in Journal of proteome research (01-03-2013)“…The bacterial ribosomal protein S12 contains a universally conserved D88 residue on a loop region thought to be critically involved in translation due to its…”
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Journal Article -
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A Proteomic and Transcriptomic Approach Reveals New Insight into β-methylthiolation of Escherichia coli Ribosomal Protein S12
Published in Molecular & cellular proteomics (01-03-2011)“…β-methylthiolation is a novel post-translational modification mapping to a universally conserved Asp 88 of the bacterial ribosomal protein S12. This S12…”
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Journal Article -
7
Cholesterol biosynthesis regulation and protein changes in rat liver following treatment with fluvastatin
Published in Toxicology letters (31-03-2001)“…The enzyme 3-hydroxy-3-methylglutaryl-coenzyme A (HMG-CoA) reductase is a key regulator in cholesterol biosynthesis and HMG CoA reductase inhibitors (statins)…”
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Journal Article Conference Proceeding -
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Composition of the Synaptic PSD-95 ComplexS
Published in Molecular & cellular proteomics (09-07-2007)“…Postsynaptic density protein 95 (PSD-95), a specialized scaffold protein with multiple protein interaction domains, forms the backbone of an extensive…”
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Journal Article -
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Toward Determining the Biological Function of a Novel Post‐translational Modification on the Ribosomal Protein S12
Published in The FASEB journal (01-04-2007)“…The ribosome is the universal macromolecular machine that translates the mRNA transcript into polypeptides. Analytical techniques have facilitated…”
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Journal Article -
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Proteomics to display lovastatin-induced protein and pathway regulation in rat liver
Published in Electrophoresis (01-06-2000)“…Lovastatin is a lipid lowering agent that acts by inhibiting 3‐hydroxy‐3‐methylglutaryl‐coenzyme A (HMG‐CoA) reductase, a key regulatory enzyme in cholesterol…”
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Journal Article