Search Results - "Makus, Julia"
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Insights into the Mechanism of Curaxin CBL0137 Epigenetic Activity: The Induction of DNA Demethylation and the Suppression of BET Family Proteins
Published in International journal of molecular sciences (01-08-2023)“…The development of malignant tumors is caused by a complex combination of genetic mutations and epigenetic alterations, the latter of which are induced by…”
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Novel missense variants in brain morphogenic genes associated with depression and schizophrenia
Published in Frontiers in psychiatry (18-04-2024)“…Impaired function of brain morphogenic genes is considered one of the predisposing factors for the manifestation of psychiatric and cognitive disorders, such…”
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Histone Methyltransferases as a New Target for Epigenetic Action of Vorinostat
Published in Biochemistry (Moscow) (01-07-2023)“…Epigenetic genome regulation during malignant cell transformation is characterized by the aberrant methylation and acetylation of histones. Vorinostat (SAHA)…”
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EPIGENETIC EFFECTS OF ENZASTAURIN – A NEW ASPECT IN THE MECHANISM OF ACTION OF AN ANTICANCER DRUG FROM PROTEIN KINASE INHIBITORS
Published in Sibirskiĭ onkologicheskiĭ zhurnal (01-09-2020)“…The purpose of the study was to analyze the ability of five antitumor drugs from the pharmaceutical group of protein kinase inhibitors (gefitinib, imatinib,…”
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