Search Results - "Makunde, Williams"
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Effect of Wuchereria bancrofti infection on HIV incidence in southwest Tanzania: a prospective cohort study
Published in The Lancet (British edition) (15-10-2016)“…Summary Background The past decades have seen an ongoing controversial debate about whether the immune activation induced by helminths has an effect on the…”
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High prevalence of epilepsy in two rural onchocerciasis endemic villages in the Mahenge area, Tanzania, after 20 years of community directed treatment with ivermectin
Published in Infectious diseases of poverty (20-06-2018)“…Epilepsy is a neurological disorder with a multitude of underlying causes, which may include infection with Onchocerca volvulus, the parasitic worm that causes…”
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Clinical presentation of epilepsy in six villages in an onchocerciasis endemic area in Mahenge, Tanzania
Published in Epileptic disorders (01-10-2019)“…ABSTRACT Aims. To describe the clinical manifestations of epilepsy and access to antiseizure treatment in Mahenge in Central Tanzania, an onchocerciasis…”
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Ivermectin treatment response in two rural villages with a high prevalence of onchocerciasis and epilepsy, Mahenge Tanzania
Published in African health sciences (01-09-2022)“…Despite 20 years of ivermectin mass distribution in the Mahenge area, Tanzania, the prevalence of onchocerciasis and epilepsy has remained high in rural…”
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Community knowledge, attitude, practices and beliefs associated with persistence of malaria transmission in North-western and Southern regions of Tanzania
Published in Malaria journal (10-10-2023)“…Despite significant decline in the past two decades, malaria is still a major public health concern in Tanzania; with over 93% of the population still at risk…”
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Macrofilaricidal activity after doxycycline treatment of Wuchereria bancrofti: a double-blind, randomised placebo-controlled trial
Published in The Lancet (British edition) (18-06-2005)“…Wolbachia endosymbionts of filarial nematodes are vital for larval development and adult-worm fertility and viability. This essential dependency on the…”
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Prevalence of Lymphatic Filariasis and Treatment Effectiveness of Albendazole/ Ivermectin in Individuals with HIV Co-infection in Southwest-Tanzania
Published in PLoS neglected tropical diseases (12-04-2016)“…Annual mass treatment with ivermectin and albendazole is used to treat lymphatic filariasis in many African countries, including Tanzania. In areas where both…”
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Evolution of epilepsy prevalence and incidence in a Tanzanian area endemic for onchocerciasis and the potential impact of community-directed treatment with ivermectin: a cross-sectional study and comparison over 28 years
Published in BMJ open (01-03-2018)“…IntroductionWorldwide, there are an estimated 50 million people affected by epilepsy. Its aetiology is manifold, and parasitic infections play an important…”
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Onchocerciasis-associated epilepsy: another piece in the puzzle from the Mahenge mountains, southern Tanzania
Published in Infectious diseases of poverty (24-05-2019)“…In a study from the onchocerciasis-endemic area of Mahenge in southern Tanzania, Mmbando et al. [Inf Dis Poverty. 2018;7:64] demonstrate that in four selected…”
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Correction: Prevalence of Lymphatic Filariasis and Treatment Effectiveness of Albendazole/ Ivermectin in Individuals with HIV Co-infection in Southwest-Tanzania
Published in PLoS neglected tropical diseases (01-08-2016)“…[This corrects the article DOI: 10.1371/journal.pntd.0004618.]…”
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Current Epidemiological Assessment of Bancroftian Filariasis in Tanga Region, Northeastern Tanzania
Published in Journal of Tropical Medicine (01-01-2016)“…Background. Tanzania started a countrywide lymphatic filariasis elimination programme in 2000 adopting the mass drug administration (MDA) strategy. The drug…”
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Prevalence and Correlates of Lymphatic Filariasis Infection and Its Morbidity Following Mass Ivermectin and Albendazole Administration in Mkinga District, North-Eastern Tanzania
Published in Journal of clinical medicine (21-05-2020)“…Lymphatic filariasis (LF) is a neglected tropical disease targeted for elimination as public health problem through morbidity management and preventive annual…”
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Retinoid Expression in Onchocercal Skin Disease: Pilot Study
Published in Infectious diseases (20-09-2017)“…Based on the observation that the parasite Onchocerca volvulus selectively absorbs vitamin A from the host, and the known toxicity of vitamin A in higher…”
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Lost to follow up and clinical outcomes of HIV adult patients on antiretroviral therapy in care and treatment centres in Tanga City, north-eastern Tanzania
Published in Tanzania journal of health research (01-10-2012)“…Scaling up of Antiretroviral (ARV) drugs is crucial and should be a perpetual venture in developing countries in-order to increase the survival period of…”
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Wolbachia bacteria in filarial immunity and disease
Published in Parasite immunology (01-07-2001)“…Lymphatic filarial nematodes are infected with endosymbiotic Wolbachia bacteria. Lipopolysaccharide from these bacteria is the major activator of innate…”
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Prevalence of onchocerciasis and epilepsy in a Tanzanian region after a prolonged community-directed treatment with ivermectin
Published in PLoS neglected tropical diseases (06-09-2024)“…Epidemiological evidence suggests that Onchocerca volvulus is associated with epilepsy, although the exact pathophysiological mechanism is unknown. Mahenge is…”
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Community knowledge, attitudes, and practices regarding epilepsy in Mahenge, Tanzania: A socio-anthropological study in an onchocerciasis-endemic area with a high prevalence of epilepsy
Published in Epilepsy & behavior (01-03-2022)“…•Epilepsy is one of the public health important diseases in Mahenge.•Traditional healers are mostly the first contacts following onset of epilepsy.•There is…”
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Lost to follow up and clinical outcomes of HIV adult patients on antiretroviral therapy in care and treatment centres in Tanga City, north-eastern Tanzania
Published in Tanzania journal of health research (11-03-2014)“…Scaling up of Antiretroviral (ARV) drugs is crucial and should be a perpetual venture in developing countries in-order to increase the survival period of…”
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