Search Results - "Maksym, Geoffrey"
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Technical standards for respiratory oscillometry
Published in The European respiratory journal (01-02-2020)“…Oscillometry (also known as the forced oscillation technique) measures the mechanical properties of the respiratory system (upper and intrathoracic airways,…”
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2
Hyperpolarized (3) He and (129) Xe MRI: differences in asthma before bronchodilation
Published in Journal of magnetic resonance imaging (01-12-2013)“…To compare hyperpolarized helium-3 ((3) He) and xenon-129 ((129) Xe) MRI in asthmatics before and after salbutamol inhalation. Seven asthmatics provided…”
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3
Defective Fibrillar Collagen Organization by Fibroblasts Contributes to Airway Remodeling in Asthma
Published in American journal of respiratory and critical care medicine (15-08-2019)“…Histologic stains have been used as the gold standard to visualize extracellular matrix (ECM) changes associated with airway remodeling in asthma, yet they…”
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Characteristics of lung resistance and elastance associated with tracheal stenosis and intrapulmonary airway narrowing in ex vivo sheep lungs
Published in Respiratory research (09-09-2024)“…Understanding the characteristics of pulmonary resistance and elastance in relation to the location of airway narrowing, e.g., tracheal stenosis vs…”
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Clinical significance and applications of oscillometry
Published in European respiratory review (31-03-2022)“…Recently, "Technical standards for respiratory oscillometry" was published, which reviewed the physiological basis of oscillometric measures and detailed the…”
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Time-Varying Respiratory Mechanics as a Novel Mechanism Behind Frequency Dependence of Impedance: A Modeling Approach
Published in IEEE transactions on biomedical engineering (01-09-2019)“…Frequency dependence of respiratory mechanics is a well-established behavior of the respiratory system and is known to be an indicator of severity of…”
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Temporal complexity in clinical manifestations of lung disease
Published in Journal of applied physiology (1985) (01-06-2011)“…In this review, we summarize results of recent research on the temporal variability of lung function, symptoms, and inflammatory biomarkers. Specifically, we…”
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Epithelial-interleukin-1 inhibits collagen formation by airway fibroblasts: Implications for asthma
Published in Scientific reports (26-05-2020)“…In asthma, the airway epithelium has an impaired capacity to differentiate and plays a key role in the development of airway inflammation and remodeling…”
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Cell-contact-mediated assembly of contractile airway smooth muscle rings
Published in Biomedical materials (Bristol) (01-03-2023)“…Microtissues in the shape of toroidal rings provide an ideal geometry to better represent the structure and function of the airway smooth muscle present in the…”
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Modelling resistance and reactance with heterogeneous airway narrowing in mild to severe asthma
Published in Canadian journal of physiology and pharmacology (01-03-2015)“…Ventilation heterogeneity is an important marker of small airway dysfunction in asthma. The frequency dependence of respiratory system resistance (Rrs) from…”
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Oscillometry and pulmonary magnetic resonance imaging in asthma and COPD
Published in Physiological reports (01-01-2019)“…Developed over six decades ago, pulmonary oscillometry has re‐emerged as a noninvasive and effort‐independent method for evaluating respiratory‐system…”
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Technical standards for respiratory oscillometry: test loads for calibration and verification
Published in The European respiratory journal (01-10-2020)Get full text
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13
Scaling the microrheology of living cells
Published in Physical review letters (01-10-2001)“…We report a scaling law that governs both the elastic and frictional properties of a wide variety of living cell types, over a wide range of time scales and…”
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14
Modeling stochastic and spatial heterogeneity in a human airway tree to determine variation in respiratory system resistance
Published in Journal of applied physiology (1985) (2012)“…Asthma is a variable disease with changes in symptoms and airway function over many time scales. Airway resistance (Raw) is variable and thought to reflect…”
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15
Extract and component‐specific sensitization patterns in Canadian moderate‐to‐severe preschool asthmatics
Published in Allergy (Copenhagen) (01-12-2019)Get full text
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16
Development and characterization of a 3D multicell microtissue culture model of airway smooth muscle
Published in American journal of physiology. Lung cellular and molecular physiology (01-01-2013)“…Airway smooth muscle (ASM) cellular and molecular biology is typically studied with single-cell cultures grown on flat 2D substrates. However, cells in vivo…”
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Characterization Of Allergen Sensitization Patterns In Canadian Preschool Children With Severe Wheezing
Published in Journal of allergy and clinical immunology (01-02-2019)Get full text
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Tracking Respiratory Mechanics With Oscillometry: Introduction of Time-Varying Error
Published in IEEE sensors journal (01-01-2019)“…Oscillometry is a useful measure of lung function and recently has been used to estimate temporal variation in physiological mechanical properties of the lung,…”
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Viscoelasticity of human alveolar epithelial cells subjected to stretch
Published in American journal of physiology. Lung cellular and molecular physiology (01-11-2004)“…Alveolar epithelial cells undergo stretching during breathing and mechanical ventilation. Stretch can modify cell viscoelastic properties, which may compromise…”
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Regional pulmonary response to a methacholine challenge using hyperpolarized (3)He magnetic resonance imaging
Published in Respirology (Carlton, Vic.) (01-11-2012)“…Spirometry is insensitive to small airway abnormalities in asthma. Our objective was to evaluate regional lung structure and function using hyperpolarized…”
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