Search Results - "Makovoz, Bar"
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Multi-species single-cell transcriptomic analysis of ocular compartment regulons
Published in Nature communications (28-09-2021)“…The retina is a widely profiled tissue in multiple species by single-cell RNA sequencing studies. However, integrative research of the retina across species is…”
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Journal Article -
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Using Postmarket Surveillance to Assess Safety-Related Events in a Digital Rehabilitation App (Kaia App): Observational Study
Published in JMIR human factors (09-11-2021)“…Low back pain (LBP) affects nearly 4 out of 5 individuals during their lifetime and is the leading cause of disability globally. Digital therapeutics are…”
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Transcriptional comparison of adult human primary Retinal Pigment Epithelium, human pluripotent stem cell-derived Retinal Pigment Epithelium, and ARPE19 cells
Published in Frontiers in cell and developmental biology (26-08-2022)“…The therapeutic potential of pluripotent stem cells is great as they promise to usher in a new era of medicine where cells or organs may be prescribed to…”
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Journal Article -
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Protocols for SARS-CoV-2 infection in primary ocular cells and eye organoids
Published in STAR protocols (17-06-2022)“…Here, we describe a series of protocols detailing the steps for evaluating SARS-CoV-2 infection in models of the human eye. Included are protocols for whole…”
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SARS-CoV-2 infects human adult donor eyes and hESC-derived ocular epithelium
Published in Cell stem cell (01-07-2021)“…The SARS-CoV-2 pandemic has caused unparalleled disruption of global behavior and significant loss of life. To minimize SARS-CoV-2 spread, understanding the…”
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Neuroectoderm-derived Iris Muscle Characterization at the Single Cell Resolution in Native Human Iris and a Pluripotent Stem Cell Whole Eye Model
Published 01-01-2021“…The iris muscle is a rare example of neuroectoderm derived muscle specification. The mechanism which enables the eye field neuroectoderm to specify the iris…”
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Dissertation -
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Highly efficient reprogrammable mouse lines with integrated reporters to track the route to pluripotency
Published in Proceedings of the National Academy of Sciences - PNAS (06-12-2022)“…Revealing the molecular events associated with reprogramming different somatic cell types to pluripotency is critical for understanding the characteristics of…”
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Journal Article -
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Considerations for the development of iPSC-derived cell therapies: a review of key challenges by the JSRM-ISCT iPSC Committee
Published in Cytotherapy (Oxford, England) (01-11-2024)“…Since their first production in 2007, human induced pluripotent stem cells (iPSCs) have provided a novel platform for the development of various cell therapies…”
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Journal Article