Search Results - "Makki, Alaa"
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1
Quantification of clinical mAb solutions using Raman spectroscopy: Macroscopic vs microscopic analysis
Published in Talanta (Oxford) (01-12-2022)Get full text
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Understanding the discrimination and quantification of monoclonal antibodies preparations using Raman spectroscopy
Published in Journal of pharmaceutical and biomedical analysis (05-02-2021)“…•Raman spectroscopy for analytical quality control of monoclonal antibodies preparations.•Understanding the origin of Raman signatures from complex therapeutic…”
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Qualitative and quantitative analysis of therapeutic solutions using Raman and infrared spectroscopy
Published in Spectrochimica acta. Part A, Molecular and biomolecular spectroscopy (05-07-2019)“…Anticancer drugs are prescribed and administrated to an increasing number of patients on a daily basis. As a consequence, a number of concerns have been raised…”
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In situ Analytical Quality Control of chemotherapeutic solutions in infusion bags by Raman spectroscopy
Published in Talanta (Oxford) (01-06-2021)“…Analytical Quality Control (AQC) in centralised preparation units of oncology centers is a common procedure relying on the identification and quantification of…”
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Cytosporone E analogues as BRD4 inhibitors for cancer treatment: molecular docking and molecular dynamic investigations
Published in Journal of biomolecular structure & dynamics (29-12-2023)“…Cancer is considered one of the worldwide life-threatening and leading causes of human mortality. In 2020, 19,292,789 cancer cases and 9,958,133 cancer deaths…”
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Phthalide derivatives as dihydrofolate reductase inhibitors for malaria: molecular docking and molecular dynamics studies
Published in Journal of biomolecular structure & dynamics (24-07-2023)“…Plasmodium falciparum dihydrofolate reductase enzyme (P. falciparum DHFR) is one of the vital drug targets for malaria treatment, as this protein is…”
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Identification of Novel Natural Dual HDAC and Hsp90 Inhibitors for Metastatic TNBC Using e-Pharmacophore Modeling, Molecular Docking, and Molecular Dynamics Studies
Published in Molecules (Basel, Switzerland) (13-02-2023)“…Breast cancer (BC) is one of the main types of cancer that endangers women's lives. The characteristics of triple-negative breast cancer (TNBC) include a high…”
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Design of Novel Phosphatidylinositol 3-Kinase Inhibitors for Non-Hodgkin's Lymphoma: Molecular Docking, Molecular Dynamics, and Density Functional Theory Studies on Gold Nanoparticles
Published in Molecules (Basel, Switzerland) (01-03-2023)“…Non-Hodgkin's lymphomas are a diverse collection of lymphoproliferative cancers that are much less predictable than Hodgkin's lymphomas with a far greater…”
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Vibrational spectroscopy for discrimination and quantification of clinical chemotherapeutic preparations
Published in Vibrational spectroscopy (01-03-2021)“…In a clinical setting, analytical quality control of the administration of chemotherapeutic preparations is required to ensure patient safety with respect to…”
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Discovery of novel potential inhibitors of TMPRSS2 and Mpro of SARS-CoV-2 using E-pharmacophore and docking-based virtual screening combined with molecular dynamic and quantum mechanics
Published in Journal of biomolecular structure & dynamics (22-09-2023)“…The pandemic of coronavirus disease is caused by the SARS-CoV-2 which is considered a global health issue. The main protease of COVID 19 (Mpro) has an…”
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Drug repurposing for SARS-CoV-2 main protease: Molecular docking and molecular dynamics investigations
Published in Biochemistry and biophysics reports (01-03-2022)“…The current novel corona virus illness (COVID-19) is a developing viral disease that was discovered in 2019. There is currently no viable therapeutic strategy…”
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Drug repurposing against main protease and RNA-dependent RNA polymerase of SARS-CoV-2 using molecular docking, MM-GBSA calculations and molecular dynamics
Published in Structural chemistry (01-10-2022)“…A virus called severe acute respiratory distress syndrome coronavirus type 2 (SARS‐CoV‐2) is the causing organism of coronavirus disease 2019 (COVID-19), which…”
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De novo design of novel spike glycoprotein inhibitors using e-pharmacophore modeling, molecular hybridization, ADMET, quantum mechanics and molecular dynamics studies for COVID-19
Published in Pakistan journal of pharmaceutical sciences (01-01-2022)“…The pandemic COVID-19, caused by SARS-COV-2, has been a global concern and burden since April 2020 due to high contagiousness and pathogenesis. A great effort…”
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The Effectiveness of Advanced Platelet-Rich Fibrin in comparison with Leukocyte-Platelet-Rich Fibrin on Outcome after Dentoalveolar Surgery
Published in International journal of dentistry (2021)“…Background and Purpose. Some physiological changes may occur following tooth extraction, and symptoms during the postextraction period may affect the patient’s…”
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Evaluation of post-extraction healing after atraumatic axial tooth extraction using Benex system II versus conventional extraction: Randomized control trial
Published in The Saudi dental journal (01-12-2021)“…Tooth extraction is critical for dental treatment complications. One of the most discussed topics is socket healing after extraction. The Benex system allows…”
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Prevalence of vulvovaginal candidiasis among pregnant women in Africa: A systematic review and meta-analysis
Published in Journal of infection in developing countries (30-08-2022)“…Introduction: Vulvovaginal candidiasis (VVC) is a yeast infection of the vulva, which is caused by Candida species and affects women worldwide. Pregnant women…”
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Global, regional, and national burden of stroke and its risk factors, 1990–2019: a systematic analysis for the Global Burden of Disease Study 2019
Published in Lancet neurology (01-10-2021)“…Regularly updated data on stroke and its pathological types, including data on their incidence, prevalence, mortality, disability, risk factors, and…”
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Population-level risks of alcohol consumption by amount, geography, age, sex, and year: a systematic analysis for the Global Burden of Disease Study 2020
Published in The Lancet (British edition) (16-07-2022)“…The health risks associated with moderate alcohol consumption continue to be debated. Small amounts of alcohol might lower the risk of some health outcomes but…”
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Global, regional, and national burden of hepatitis B, 1990-2019: a systematic analysis for the Global Burden of Disease Study 2019
Published in The lancet. Gastroenterology & hepatology (01-09-2022)“…Combating viral hepatitis is part of the UN Sustainable Development Goals (SDGs), and WHO has put forth hepatitis B elimination targets in its Global Health…”
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Measuring routine childhood vaccination coverage in 204 countries and territories, 1980–2019: a systematic analysis for the Global Burden of Disease Study 2020, Release 1
Published in The Lancet (British edition) (07-08-2021)“…Measuring routine childhood vaccination is crucial to inform global vaccine policies and programme implementation, and to track progress towards targets set by…”
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