Search Results - "Makkan, Heeran"
-
1
High HIV incidence among young women in South Africa: Data from a large prospective study
Published in PloS one (03-06-2022)“…South Africa has the highest national burden of HIV globally. Understanding drivers of HIV acquisition in recently completed, prospective studies in which HIV…”
Get full text
Journal Article -
2
High STI burden among a cohort of adolescents aged 12-19 years in a youth-friendly clinic in South Africa
Published in PloS one (10-07-2024)“…Adolescents face a higher risk for HIV, STIs, and unintended pregnancy than any other age group in sub-Saharan Africa, and have unique health care needs as…”
Get full text
Journal Article -
3
High Levels of Pretreatment HIV-1 Drug Resistance Mutations Among South African Women Who Acquired HIV During a Prospective Study
Published in Journal of acquired immune deficiency syndromes (1999) (01-10-2022)“…Background: Pretreatment HIV drug resistance (PDR) undermines individual treatment success and threatens the achievement of UNAIDS 95-95-95 targets. In many…”
Get full text
Journal Article -
4
Age-Specific Risk Scores Do Not Improve HIV-1 Prediction Among Women in South Africa
Published in Journal of acquired immune deficiency syndromes (1999) (01-10-2020)“…BACKGROUND:HIV-1 risk scoring tools could help target provision of prevention modalities such as pre-exposure prophylaxis. Recent research suggests that risk…”
Get full text
Journal Article -
5
Control of the HIV-1 Load Varies by Viral Subtype in a Large Cohort of African Adults With Incident HIV-1 Infection
Published in The Journal of infectious diseases (02-07-2019)“…Few human immunodeficiency virus (HIV)-infected persons can maintain low viral levels without therapeutic intervention. We evaluate predictors of spontaneous…”
Get full text
Journal Article -
6
Attitudes Toward Gender-Based Violence Among Sexually Active Adult Men at High Risk for HIV in Rustenburg, South Africa
Published in American journal of men's health (01-05-2022)“…Gender-based violence (GBV) toward women is widespread and has been associated with increased HIV risk. We investigated attitudes toward GBV among men living…”
Get full text
Journal Article -
7
HIV incidence and predictors of inconsistent condom use among adult men enrolled into an HIV vaccine preparedness study, Rustenburg, South Africa
Published in PloS one (03-04-2019)“…Understanding HIV incidence and risk behaviour among populations being considered for HIV vaccine studies is necessary for the appropriate design of trials…”
Get full text
Journal Article -
8
Creating an African HIV clinical research and prevention trials network: HIV prevalence, incidence and transmission
Published in PloS one (20-01-2015)“…HIV epidemiology informs prevention trial design and program planning. Nine clinical research centers (CRC) in sub-Saharan Africa conducted HIV observational…”
Get full text
Journal Article -
9
Failure of a novel, rapid antigen and antibody combination test to detect antigen-positive HIV infection in African adults with early HIV infection
Published in PloS one (08-06-2012)“…Acute HIV infection (prior to antibody seroconversion) represents a high-risk window for HIV transmission. Development of a test to detect acute infection at…”
Get full text
Journal Article -
10
Pregnancy incidence and correlates in a clinical trial preparedness study, North West Province South Africa
Published in PloS one (06-05-2014)“…Women in HIV prevention trials often must typically agree to avoid pregnancy. Regardless, some become pregnant. Screening tools predicting pregnancy risk could…”
Get full text
Journal Article -
11
Cohort Profile: IAVI’s HIV epidemiology and early infection cohort studies in Africa to support vaccine discovery
Published in International journal of epidemiology (03-03-2021)Get full text
Journal Article -
12
The Dawn of Human Matrilineal Diversity
Published in American journal of human genetics (01-05-2008)“…The quest to explain demographic history during the early part of human evolution has been limited because of the scarce paleoanthropological record from the…”
Get full text
Journal Article -
13
High STI burden among a cohort of adolescents aged 12-19 years in a youth-friendly clinic in South Africa
Published in PloS one (01-01-2024)“…Adolescents face a higher risk for HIV, STIs, and unintended pregnancy than any other age group in sub-Saharan Africa, and have unique health care needs as…”
Get full text
Journal Article -
14
Sequencing Mycobacteria and Algorithm-determined Resistant Tuberculosis Treatment (SMARTT): a study protocol for a phase IV pragmatic randomized controlled patient management strategy trial
Published in Current controlled trials in cardiovascular medicine (08-10-2022)“…Abstract Background Rifampicin-resistant tuberculosis (RR-TB) remains an important global health problem. Ideally, the complete drug-resistance profile guides…”
Get full text
Journal Article -
15
High HIV incidence among young women in South Africa: Data from a large prospective study
Published in PloS one (01-01-2022)“…IntroductionSouth Africa has the highest national burden of HIV globally. Understanding drivers of HIV acquisition in recently completed, prospective studies…”
Get full text
Journal Article -
16
Development of a single base extension method to resolve Y chromosome haplogroups in sub-Saharan African populations
Published in Investigative genetics (01-09-2010)“…The ability of the Y chromosome to retain a record of its evolution has seen it become an essential tool of molecular anthropology. In the last few years,…”
Get full text
Journal Article -
17
Pregnancy Incidence and Correlates in a Clinical Trial Preparedness Study, North West Province South Africa: e95708
Published in PloS one (01-05-2014)“…Introduction Women in HIV prevention trials often must typically agree to avoid pregnancy. Regardless, some become pregnant. Screening tools predicting…”
Get full text
Journal Article -
18
Mitochondrial HVRI and whole mitogenome sequence variations portray similar scenarios on the genetic structure and ancestry of northeast Africans
Published in Meta Gene (01-02-2021)“…A significant portion of the current human adaptive and demographic traits is believed to have originated in north-east Africa, the putative scene of early…”
Get full text
Journal Article