Search Results - "Makitie, Laura"

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  1. 1

    Expression of ODC Antizyme Inhibitor 2 (AZIN2) in Human Secretory Cells and Tissues by Rasila, Tiina, Lehtonen, Alexandra, Kanerva, Kristiina, Mäkitie, Laura T, Haglund, Caj, Andersson, Leif C

    Published in PloS one (10-03-2016)
    “…Ornithine decarboxylase (ODC) antizyme inhibitor 2 (AZIN2), originally called ODCp, is a regulator of polyamine synthesis that we originally identified and…”
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    Journal Article
  2. 2

    Expression of antizyme inhibitor 2 in mast cells and role of polyamines as selective regulators of serotonin secretion by Kanerva, Kristiina, Lappalainen, Jani, Mäkitie, Laura T, Virolainen, Susanna, Kovanen, Petri T, Andersson, Leif C

    Published in PloS one (31-08-2009)
    “…Upon IgE-mediated activation, mast cells (MC) exocytose their cytoplasmic secretory granules and release a variety of bioactive substances that trigger…”
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    Journal Article
  3. 3

    Human ornithine decarboxylase paralogue (ODCp) is an antizyme inhibitor but not an arginine decarboxylase by Kanerva, Kristiina, Mäkitie, Laura T, Pelander, Anna, Heiskala, Marja, Andersson, Leif C

    Published in Biochemical journal (01-01-2008)
    “…ODC (ornithine decarboxylase), the rate-limiting enzyme in polyamine biosynthesis, is regulated by specific inhibitors, AZs (antizymes), which in turn are…”
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    Journal Article
  4. 4

    Brain Neurons Express Ornithine Decarboxylase-Activating Antizyme Inhibitor 2 with Accumulation in Alzheimer's Disease by Mäkitie, Laura T., Kanerva, Kristiina, Polvikoski, Tuomo, Paetau, Anders, Andersson, Leif C.

    Published in Brain pathology (Zurich, Switzerland) (01-05-2010)
    “…Polyamines are small cationic molecules that in adult brain are connected to neuronal signaling by regulating inward‐rectifier K+‐channels and different…”
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    Journal Article
  5. 5

    Ornithine decarboxylase antizyme inhibitor 2 regulates intracellular vesicle trafficking by Kanerva, Kristiina, Mäkitie, Laura T., Bäck, Nils, Andersson, Leif C.

    Published in Experimental cell research (01-07-2010)
    “…Antizyme inhibitor 1 (AZIN1) and 2 (AZIN2) are proteins that activate ornithine decarboxylase (ODC), the key enzyme of polyamine biosynthesis. Both AZINs…”
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    Journal Article
  6. 6

    High expression of antizyme inhibitor 2, an activator of ornithine decarboxylase in steroidogenic cells of human gonads by Mäkitie, Laura T, Kanerva, Kristiina, Sankila, Anna, Andersson, Leif C

    Published in Histochemistry and cell biology (01-12-2009)
    “…High activity of ornithine decarboxylase (ODC), the rate-limiting enzyme of polyamine synthesis, is typically present in rapidly proliferating normal and…”
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    Journal Article
  7. 7

    Ornithine decarboxylase regulates the activity and localization of rhoA via polyamination by Mäkitie, Laura T., Kanerva, Kristiina, Andersson, Leif C.

    Published in Experimental cell research (01-04-2009)
    “…Ornithine decarboxylase (ODC) is the rate-limiting enzyme of polyamine synthesis. Polyamines and ODC are connected to cell proliferation and transformation…”
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    Journal Article
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  10. 10

    Effects of a Digital Care Pathway for Multiple Sclerosis: Observational Study by Vesinurm, Märt, Maunula, Anna, Olli, Päivi, Lillrank, Paul, Ijäs, Petra, Torkki, Paulus, Mäkitie, Laura, Laakso, Sini M

    Published in JMIR human factors (07-08-2024)
    “…Helsinki University Hospital has developed a digital care pathway (DCP) for people with multiple sclerosis (MS) to improve the care quality. DCP was designed…”
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    Journal Article
  11. 11

    Navigating the Complexities of Discrete Choice Experiments in Parkinson's Disease Patients by Godoy, Carlos, Makitie, Laura, Fiorenzato, Eleonora, Koivu, Maija, Bakker, Lytske Jantien, Groot, Carin Uyl-de, Redekop, William Ken, van Deen, Welmoed Kirsten

    “…Background Discrete Choice Experiments (DCEs) are a popular and powerful method for measuring preferences across various fields. Their success relies on…”
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    Journal Article
  12. 12

    Expression of ODC Antizyme Inhibitor 2 by Rasila, Tiina, Lehtonen, Alexandra, Kanerva, Kristiina, Mäkitie, Laura T, Haglund, Caj, Andersson, Leif C

    Published in PloS one (10-03-2016)
    “…Ornithine decarboxylase (ODC) antizyme inhibitor 2 (AZIN2), originally called ODCp, is a regulator of polyamine synthesis that we originally identified and…”
    Get full text
    Journal Article
  13. 13

    Abstract WMP62: Remote Home Monitoring of Risk Factors After Stroke or TIA to Improve Secondary Prevention - A Pilot Study by Ijas, Petra, Mäkitie, Laura, Kivelä, Satu, Wahlman-Muranen, Taina, Kiukkonen, Niko, Selonen, Petri, Stirbu, Vlad, Taivalsaari, Antero, Myyryläinen, Lea, Koskimies, Oskari, Honkanen, Mauri, Forss, Nina

    Published in Stroke (1970) (22-01-2018)
    “…Abstract only Background: Up to 90% of strokes could be prevented by effective treatment of the risk factors. However, there are major problems with the…”
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    Journal Article
  14. 14

    Headache as symptom of intracranial hemorrhage by Mäkitie, Laura, Korja, Miikka, Kangasniemi, Marko, Kallela, Mikko, Forss, Nina, Niemelä, Mika, Lindsberg, Perttu J

    “…The most important signs of danger of a headache patient include exceptionally intense or acute headache, transient loss or progressive impairment of…”
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    Magazine Article