Search Results - "Makino, Yasukazu"

An association study of C9orf3, a novel component of the renin-angiotensin system, and hypertension in diabetes by Ichikawa, Mai, Konoshita, Tadashi, Makino, Yasukazu, Suzuki, Jinya, Ishizuka, Tamotsu, Nakamura, Hiroyuki

“…The renin-angiotensin system (RAS) is important in the onset and course of cardiovascular, kidney, and metabolic disorders. Previous reports showed that the…”
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Synergistic Expression of Angiotensin-Converting Enzyme (ACE) and ACE2 in Human Renal Tissue and Confounding Effects of Hypertension on the ACE to ACE2 Ratio by Wakahara, Shigeyuki, Konoshita, Tadashi, Mizuno, Shinichi, Motomura, Makoto, Aoyama, Chikako, Makino, Yasukazu, Kato, Norihiro, Koni, Ichiro, Miyamori, Isamu

“…Angiotensin-converting enzyme (ACE) 2, a newly emerging component of the renin-angiotensin system, is presumed to be a counterregulator against ACE in…”
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A Genetic Variant in the Distal Enhancer Region of the Human Renin Gene Affects Renin Expression by Makino, Yasukazu, Konoshita, Tadashi, Omori, Atsuhito, Maegawa, Nobuhiro, Nakaya, Takahiro, Ichikawa, Mai, Yamamoto, Katsushi, Wakahara, Shigeyuki, Ishizuka, Tamotsu, Onoe, Tamehito, Nakamura, Hiroyuki

“…The high heritability of plasma renin activity was confirmed in recent investigations. A variation located near the strong enhancer of the human renin gene…”
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A crossover comparison of urinary albumin excretion as a new surrogate marker for cardiovascular disease among 4 types of calcium channel blockers by Konoshita, Tadashi, Makino, Yasukazu, Kimura, Tomoko, Fujii, Miki, Morikawa, Norihiro, Wakahara, Shigeyuki, Arakawa, Kenichiro, Inoki, Isao, Nakamura, Hiroyuki, Miyamori, Isamu

“…Abstract Background At the intervention for cardiovascular disease (CVD), albuminuria is a new pivotal target. Calcium channel blocker (CCB) is one of the most…”
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On the top of ARB N/L type Ca channel blocker leads to less elevation of aldosterone by Konoshita, Tadashi, Kaeriyama, Saori, Urabe, Machi, Nakaya, Takahiro, Yamada, Mika, Ichikawa, Mai, Yamamoto, Katsushi, Sato, Satsuki, Imagawa, Michiko, Fujii, Miki, Makino, Yasukazu, Zenimaru, Yasuo, Wakahara, Shigeyuki, Suzuki, Jinya, Ishizuka, Tamotsu, Nakamura, Hiroyuki

“…The activation of the renin-angiotensin system (RAS) is one of the unfavourable characteristics of calcium channel blocker (CCB). N type calcium channel is…”
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Genetic variant of the renin-angiotensin system and prevalence of type 2 diabetes mellitus: a modest but significant effect of aldosterone synthase by Ichikawa, Mai, Konoshita, Tadashi, Nakaya, Takahiro, Yamamoto, Katsushi, Yamada, Mika, Sato, Satsuki, Imagawa, Michiko, Makino, Yasukazu, Fujii, Miki, Zenimaru, Yasuo, Arakawa, Kenichiro, Suzuki, Jinya, Ishizuka, Tamotsu, Nakamura, Hiroyuki

“…Recent genome-wide association studies have identified multiple variants that confer risk of type 2 diabetes mellitus (DM). However, established associations…”
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Genetic Variant of the Renin-Angiotensin System and Diabetes Influences Blood Pressure Response to Angiotensin Receptor Blockers by Konoshita, Tadashi, Kato, Norihiro, Fuchs, Sébastien, Mizuno, Shinichi, Aoyama, Chikako, Motomura, Makoto, Makino, Yasukazu, Wakahara, Shigeyuki, Inoki, Isao, Miyamori, Isamu, Pinet, Florence

“…OBJECTIVE: Recent studies have proven the favorable effects of angiotensin receptor blockers (ARBs) on cardiovascular and renal disorders. However,…”
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Tissue Gene Expression of Renin-Angiotensin System in Human Type 2 Diabetic Nephropathy by Konoshita, Tadashi, Wakahara, Shigeyuki, Mizuno, Shinichi, Motomura, Makoto, Aoyama, Chikako, Makino, Yasukazu, Kawai, Yasuyuki, Kato, Norihiro, Koni, Ichiro, Miyamori, Isamu, Mabuchi, Hiroshi

“…OBJECTIVE:--Recent studies have proved that blockade of the renin-angiotensin system (RAS) retards the progression of diabetic nephropathy, whereas…”
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Angiokeratomas in Fabry Disease by Mutoh, Hisao, MD, PhD, Onoe, Tamehito, MD, PhD, Makino, Yasukazu, MD, Arakawa, Kenichiro, MD, PhD, Nakamura, Hiroyuki, MD, PhD, Konoshita, Tadashi, MD, PhD

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A proximal direct repeat motif characterized as a negative regulatory element in the human renin gene by Konoshita, Tadashi, Fuchs, Sébastien, Makino, Yasukazu, Wakahara, Shigeyuki, Miyamori, Isamu

“…The regulation of renin gene expression is thought to be fundamental to regulation of the total renin–angiotensin system. The human renin gene contains a…”
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Candidate cis-elements for human renin gene expression in the promoter region by Konoshita, Tadashi, Makino, Yasukazu, Wakahara, Shigeyuki, Ido, Kanako, Yoshida, Masahiro, Kawai, Yasuyuki, Miyamori, Isamu

“…The regulation of renin gene expression, the rate‐limiting enzyme of the system, is thought to be fundamental to the total system. Previously, we mapped six…”
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ESTABLISHMENT OF A NEW SPECIFIC HIGH SENSITIVITY MEASUREMENT SYSTEM FOR SOLUBLE ANGIOTENSIN IV RECEPTOR by Konoshita, Tadashi, Azuma, Shinichiro, Sugiyama, Mitsutoshi, Furutani, Machi, Kaeriyama, Saori, Saito, Rie, Sato, Satsuki, Imagawa, Michiko, Zenimaru, Yasuo, Suzuki, Jinya, Fujii, Miki, Makino, Yasukazu

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A new-generation N/L-type calcium channel blocker leads to less activation of the renin―angiotensin system compared with conventional L type calcium channel blocker by KONOSHITA, Tadashi, MAKINO, Yasukazu, KIMURA, Tomoko, FUJII, Miki, WAKAHARA, Shigeyuki, ARAKAWA, Kenichiro, INOKI, Isao, NAKAMURA, Hiroyuki, MIYAMORI, Isamu

“…Calcium channel blocker (CCB) is one of the most useful antihypertensive agents. However, the activation of the renin-angiotensin system (RAS) is an…”
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Determinants of Plasma Renin Activity: Role of a Human Renin Gene Variant as a Genetic Factor by Konoshita, Tadashi, Nakaya, Takahiro, Sakai, Ai, Yamada, Mika, Ichikawa, Mai, Sato, Satsuki, Imagawa, Michiko, Fujii, Miki, Yamamoto, Katsushi, Makino, Yasukazu, Arakawa, Kenichiro, Suzuki, Jinya, Ishizuka, Tamotsu

“…The plasma renin activity (PRA) is affected by a number of environmental factors. However, significant heritability has been shown for the activity. A…”
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Blue toe in a male with cholesterol embolisation syndrome by Arakawa, Kenichiro, Konoshita, Tadashi, Makino, Yasukazu, Ishizuka, Tamotsu

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Image of the month: Blue toe in a male with cholesterol embolisation syndrome by ARAKAWA, Kenichiro, KONOSHITA, Tadashi, MAKINO, Yasukazu, ISHIZUKA, Tamotsu

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GENETIC VARIANT OF THE RENIN-ANGIOTENSIN-ALDOSTERONE SYSTEM (RAAS) AND RENAL SURVIVAL IN JAPANESE PATIENTS WITH CHRONIC KIDNEY DISEASE (CKD): PP.8.193 by Makino, Yasukazu, Konoshita, Tadashi, Kimura, Tomoko, Fujii, Miki, Wakahara, Shigeyuki

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A Genetic Variant in the Distal Enhancer Region of the Human Renin Gene Affects Renin Expression: e0137469 by Makino, Yasukazu, Konoshita, Tadashi, Omori, Atsuhito, Maegawa, Nobuhiro, Nakaya, Takahiro, Ichikawa, Mai, Yamamoto, Katsushi, Wakahara, Shigeyuki, Ishizuka, Tamotsu, Onoe, Tamehito

“…Background The high heritability of plasma renin activity was confirmed in recent investigations. A variation located near the strong enhancer of the human…”
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Rapid remission of minimal change disease with angiotensin II antagonist treatment in a type 1 diabetic patient with no diabetic nephropathy by Takahashi, Naoki, Kimura, Hideki, Nishi, Shinichi, Yamamoto, Chie, Kawajiri, Yumiko, Makino, Yasukazu, Konoshita, Tadashi, Miyamori, Isamu, Yoshida, Haruyoshi

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