Search Results - "Makiguchi, Miaki"
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Molecular and functional characterization of flavin-containing monooxygenases in pigs, dogs, and cats
Published in Biochemical pharmacology (01-08-2022)“…[Display omitted] Flavin-containing monooxygenases (FMOs) are drug-oxygenating enzymes that are present in the human genome as FMO1-5 and FMO6P. Among pig,…”
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Variants of Flavin-Containing Monooxygenase 3 Found in Subjects in an Updated Database of Genome Resources
Published in Drug metabolism and disposition (01-07-2023)“…Single-nucleotide substitutions of human flavin-containing monooxygenase 3 ( ) identified in the whole-genome sequences of the updated Japanese population…”
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Rare but impaired flavin-containing monooxygenase 3 (FMO3) variants reported in a recently updated Japanese mega-databank of genome resources
Published in Drug metabolism and pharmacokinetics (01-04-2024)“…Genetic variants of human flavin-containing monooxygenase 3 (FMO3) were investigated using an updated Japanese population panel containing 54,000 subjects (the…”
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A family study of compound variants of flavin-containing monooxygenase 3 (FMO3) in Japanese subjects found by urinary phenotyping for trimethylaminuria
Published in Drug metabolism and pharmacokinetics (01-06-2023)“…Phenotype–gene analyses and the increasing availability of mega-databases have revealed the impaired human flavin-containing monooxygenase 3 (FMO3) variants…”
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Simple confirmation methods for rare but impaired variants of human flavin-containing monooxygenase 3 (FMO3) found in an updated genome resource databank
Published in Drug metabolism and pharmacokinetics (01-12-2023)“…Forty-seven new nonsense or missense human flavin-containing monooxygenase 3 (FMO3) variants were recently identified in an updated Japanese population…”
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Further survey of genetic variants of flavin-containing monooxygenase 3 (FMO3) in Japanese subjects found in an updated database of genome resources and identified by phenotyping for trimethylaminuria
Published in Drug metabolism and pharmacokinetics (01-10-2022)“…The number of single-nucleotide substitutions of human flavin-containing monooxygenase 3 (FMO3) recorded in mega-databases is increasing. Moreover,…”
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Synovial fluid and plasma concentrations of tedizolid in patients with osteoarthritis infected with Staphylococcus aureus effectively determined with fluorescence detection
Published in Journal of pharmaceutical health care and sciences (10-10-2023)“…Background Tedizolid is a new oxazolidinone antibiotic with high potency for the treatment of infections caused by methicillin-resistant Staphylococcus aureus…”
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Plasma and synovial fluid concentrations of linezolid in patients with knee osteoarthritis infected with Staphylococcus aureus
Published in Journal of pharmaceutical health care and sciences (01-07-2022)“…Background Linezolid is a new oxazolidinone antibiotic used for infections caused by methicillin-resistant Staphylococcus and other species. Case presentation…”
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Quinuclidine N -Oxygenation Mediated by Flavin-Containing Monooxygenases 1 and 3 in Kidney and Liver Microsomes from Humans, Monkeys, Dogs, and Pigs
Published in Drug metabolism and disposition (01-08-2024)“…Flavin-containing monooxygenases (FMOs) are a family of enzymes that are involved in the oxygenation of heteroatom-containing molecules. In humans, FMO3 is the…”
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Molecular and functional characterization of flavin-containing monooxygenases (FMO1–6) in tree shrews
Published in Comparative biochemistry and physiology. Toxicology & pharmacology (01-03-2024)“…Flavin-containing monooxygenases (FMOs) are a family of important drug oxygenation enzymes that, in humans, consist of five functional enzymes (FMO1–5) and a…”
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Quinuclidine N -oxygenation mediated by flavin-containing monooxygenase (FMO) 1 and FMO3 in kidney and liver microsomes from humans, monkeys, dogs, and pigs
Published in Drug metabolism and disposition (20-05-2024)“…Flavin-containing monooxygenases (FMOs) are a family of enzymes that are involved in the oxygenation of heteroatom-containing molecules. In humans, FMO3 is the…”
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