Search Results - "Makarovsky, Igor"

Synthesis and preliminary biological evaluation of gabactyzine, a benactyzine-GABA mutual prodrug, as an organophosphate antidote by Weitman, Michal, Eisenkraft, Arik, TaShma, Zeev, Makarovsky, Igor, Last, David, Daniels, Dianne, Guez, David, Shneor, Ran, Mardor, Yael, Nudelman, Abraham, Krivoy, Amir

“…Organophosphates (OPs) are inhibitors of acetylcholinesterase and have deleterious effects on the central nervous system. Clinical manifestations of OP…”
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Prevention of organophosphate-induced chronic epilepsy by early benzodiazepine treatment by Shrot, Shai, Ramaty, Erez, Biala, Yoav, Bar-Klein, Guy, Daninos, Moshe, Kamintsky, Lyn, Makarovsky, Igor, Statlender, Liran, Rosman, Yossi, Krivoy, Amir, Lavon, Ophir, Kassirer, Michael, Friedman, Alon, Yaari, Yoel

“…Highlights • We induced status epilepticus (SE) with high dose of the agricultural organophosphate (OP) paraoxon. • A single episode of OP-induced SE in rats…”
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Carbamate poisoning: treatment recommendations in the setting of a mass casualties event by Rosman, Yossi, MD, Makarovsky, Igor, MSc, Bentur, Yedidia, MD, Shrot, Shai, MD, Dushnistky, Tsvika, MD, Krivoy, Amir, MD

“…Abstract The threat of using chemical compounds by terrorists as weapons of mass casualties has been a rising concern in recent years. Carbamates, a group of…”
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Novel Triclosan-Bound Hybrid-Silica Nanoparticles and their Enhanced Antimicrobial Properties by Makarovsky, Igor, Boguslavsky, Yonit, Alesker, Maria, Lellouche, Jonathan, Banin, Ehud, Lellouche, Jean-Paul

“…The design and synthesis of novel hybrid‐silica nanoparticles (NPs) containing the FDA‐approved antimicrobial triclosan (Irgasan) covalently linked within the…”
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Early in vivo MR spectroscopy findings in organophosphate-induced brain damage-potential biomarkers for short-term survival by Shrot, Shai, Anaby, Debbie, Krivoy, Amir, Makarovsky, Igor, Rosman, Yossi, Bloch-Shilderman, Eugenia, Lazar, Shlomi, Bar-shir, Amnon, Cohen, Yoram

“…Organophosphates are highly toxic substances, which cause severe brain damage. The hallmark of the brain injury is major convulsions. The goal of this study…”
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Novel Prodrugs of Tegafur that Display Improved Anticancer Activity and Antiangiogenic Properties by Engel, Dikla, Nudelman, Abraham, Tarasenko, Nataly, Levovich, Inesa, Makarovsky, Igor, Sochotnikov, Segev, Tarasenko, Igor, Rephaeli, Ada

“…New and more potent prodrugs of the 5-fluorouracyl family derived by hydroxymethylation or acyloxymethylation of…”
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Ammonia--when something smells wrong by Makarovsky, Igor, Markel, Gal, Dushnitsky, Tsvika, Eisenkraft, Arik

“…Ammonia is a common household and industrial chemical. In the medical literature and the electronic press there are many descriptions of accidental spills of…”
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Strychnine--a killer from the past by Makarovsky, Igor, Markel, Gal, Hoffman, Azik, Schein, Ophir, Brosh-Nissimov, Tal, Tashma, Zeev, Dushnitsky, Tsvika, Eisenkraft, Arik

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Hydrogen fluoride--the protoplasmic poison by Makarovsky, Igor, Markel, Gal, Dushnitsky, Tsvika, Eisenkraft, Arik

“…HF is a corrosive mineral acid. It has extremely harmful systemic effects through any route of exposure. In dilute solutions the onset of symptoms is latent…”
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Improved Triclosan Delivery by a Novel Silica-Based Nanocomposite by Makarovsky, Igor, Lellouche, Jonathan, Lellouche, Jean-Paul, Banin, Ehud

“…In this study, we report on the design, synthesis, and full characterization of a covalently‐linked, triclosan silica‐based nanoparticles (T‐SNPs), coated with…”
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Hydrazine--the space era agent by Makarovsky, Igor, Markel, Gal, Dushnitsky, Tsvika, Eisenkraft, Arik

“…Hydrazine is considered a dangerous toxic compound. It is flammable, easily ignitable and may explode upon contact with different materials, including…”
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Osmium tetroxide: a new kind of weapon by Makarovsky, Igor, Markel, Gal, Hoffman, Azik, Schein, Ophir, Finkelstien, Arseny, Brosh-Nissimov, Tal, Tashma, Zeev, Dushnitsky, Tsvika, Eisenkraft, Arik

“…OsO4 is a powerful oxidizer. It affects mainly the skin and mucous membranes. Although unsuitable for a large-scale terrorist attack, mainly due to its…”
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Bromine--the red cloud approaching by Makarovsky, Igor, Markel, Gal, Hoffman, Azik, Schein, Ophir, Brosh-Nissimov, Tal M, Finkelstien, Arseny, Tashma, Zeev, Dushnitsky, Tsvika, Eisenkraft, Arik

“…Bromine is a strong and prevalent irritating agent that can spread both as liquid and as fumes. It has a characteristic reddish-brown color. The mainstay of…”
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