Search Results - "Makó, Attila"

Optimization of Novel α7 Nicotinic Acetylcholine Receptor Positive Allosteric Modulators and the Discovery of a Preclinical Development Candidate Molecule (RGH-560) by Ledneczki, István, Némethy, Zsolt, Molnár, Katalin Dudásné, Tapolcsányi, Pál, Ilkei, Viktor, Vágó, István, Kolok, Sándor, Thán, Márta, Laszy, Judit, Balázs, Ottilia, Krámos, Balázs, Szigetvári, Áron, Bata, Imre, Makó, Attila, Visegrády, András, Fodor, László, Vastag, Mónika, Lévay, György, Lendvai, Balázs, Greiner, István, Éles, János

“…During optimization of a previously identified lead compound, attempts were made to optimize the reactive indole structural element, the suboptimal metabolic…”
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Novel-Type GABAB PAMs: Structure–Activity Relationship in Light of the Protein Structure by Krámos, Balázs, Hadady, Zsuzsa, Makó, Attila, Szántó, Gábor, Felföldi, Nóra, Magdó, Ildikó, Bobok, Amrita Ágnes, Bata, Imre, Román, Viktor, Visegrády, András, Keserű, György M., Greiner, István, Éles, János

“…Selecting a known HTS hit with the pyrazolo­[1,5-a]­pyrimidine core, our project was started from CMPPE, and its optimization was driven by a ligand-based…”
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New V1a receptor antagonist. Part 1. Synthesis and SAR development of urea derivatives by Szántó, Gábor, Makó, Attila, Baska, Ferenc, Bozó, Éva, Domány-Kovács, Katalin, Kurkó, Dalma, Cselenyák, Attila, Mohácsi, Réka, Kordás, Krisztina Szondiné, Bata, Imre

“…[Display omitted] Solid preclinical evidence links vasopressin to social behavior in animals, so, extensive work has been initiated to find new vasopressin V1a…”
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New P2X3 receptor antagonists. Part 2: Identification and SAR of quinazolinones by Szántó, Gábor, Makó, Attila, Vágó, István, Hergert, Tamás, Bata, Imre, Farkas, Bence, Kolok, Sándor, Vastag, Mónika

“…[Display omitted] Numerous potent P2X3 antagonists have been discovered and the therapeutic potential of P2X3 antagonism already comprises proof-of-concept…”
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New P2X3 receptor antagonists. Part 1: Discovery and optimization of tricyclic compounds by Szántó, Gábor, Makó, Attila, Bata, Imre, Farkas, Bence, Kolok, Sándor, Vastag, Mónika, Cselenyák, Attila

“…[Display omitted] Purinergic P2X3 receptors are trimeric ligand-gated ion channels whose antagonism is an appealing yet challenging and not fully validated…”
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Asymmetric epoxidation of substituted chalcones and chalcone analogues catalyzed by α- d-glucose- and α- d-mannose-based crown ethers by Makó, Attila, Rapi, Zsolt, Keglevich, György, Szöllősy, Áron, Drahos, László, Hegedűs, László, Bakó, Péter

“…The chiral monoaza-15-crown-5 lariat ethers annellated to methyl-4,6- O-benzylidene-α- d-glucopyranoside- 1 or mannopyranoside 2 have been applied as…”
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Theoretical study of the asymmetric phase-transfer mediated epoxidation of chalcone catalyzed by chiral crown ethers derived from monosaccharides by Makó, Attila, Menyhárd, Dóra K., Bakó, Péter, Keglevich, György, Tőke, László

“…The synthesis of a novel, optically active crown ether derived from α- d-altropyranoside is described. A significantly different asymmetric induction was…”
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Synthesis of methyl-α-d-glucopyranoside-based azacrown ethers and their application in enantioselective reactions by Makó, Attila, Szöllősy, Áron, Keglevich, György, Menyhárd, Dóra K., Bakó, Péter, Tőke, László

“…New chiral monoaza-15-crown-5 compounds anellated to methyl-4,6- O -(1-naphthyl)methylene-α- d -glucopyranoside ( 2a – 2b ), to methyl-4,6- O…”
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Synthesis of chiral pyridino-15-crown-5 type ligands containing α-D-hexapyranoside unit and their application in asymmetric synthesis by Makó, Attila, Bakó, Péter, Szöllősy, Áron, Bakó, Tibor, Peltz, Csaba, Keglevich, Péter

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Circular dichroism spectra of trans-chalcone epoxides by Pál, Krisztina, Kállay, Mihály, Kubinyi, Miklós, Bakó, Péter, Makó, Attila

“…The electronic absorption and CD spectra of (−)- trans-chalcone epoxide and its derivatives with methyl and alkoxy substituents at the ortho-positions of the…”
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Alkali Metal- and Ammonium Picrate Extraction and Complex Forming Capabilities of d-Glucose and d-Mannose-based Lariat Ethers by BAKÓ, PÉTER, MAKÓ, ATTILA, KEGLEVICH, GYÖRGY, MENYHÁRT, DÓRA K., SEFCSIK, TAMÁS, FEKETE, JENŐ

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Novel-Type GABA B PAMs: Structure-Activity Relationship in Light of the Protein Structure by Krámos, Balázs, Hadady, Zsuzsa, Makó, Attila, Szántó, Gábor, Felföldi, Nóra, Magdó, Ildikó, Bobok, Amrita Ágnes, Bata, Imre, Román, Viktor, Visegrády, András, Keserű, György M, Greiner, István, Éles, János

“…Selecting a known HTS hit with the pyrazolo[1,5- ]pyrimidine core, our project was started from CMPPE, and its optimization was driven by a ligand-based…”
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Synthesis of d-mannose-based azacrown ethers and their application in enantioselective reactions by Bakó, Péter, Makó, Attila, Keglevich, György, Kubinyi, Miklós, Pál, Krisztina

“…[Display omitted] New chiral monoaza-15-crown-5 compounds anellated to methyl-4,6- O-benzylidene-α- d-mannopyranosides 2a– f have been synthesized. These crown…”
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Phase-transfer catalyzed asymmetric epoxidation of chalcones using chiral crown ethers derived from d-glucose, d-galactose, and d-mannitol by Bakó, Tibor, Bakó, Péter, Keglevich, György, Bombicz, Petra, Kubinyi, Miklós, Pál, Krisztina, Bodor, Sándor, Makó, Attila, Tőke, László

“…Epoxidation with tert-butylhydroperoxide of chalcones catalyzed by d-glucose-based crown ethers 1 yielded the (2 R,3 S)-products in 81–92% ee. Chiral…”
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Monoszacharid-alapú királis koronaéterek szintézise és alkalmazása enantioszelektív reakciókban by Attila, Makó

“…Doktori munkám célja volt új, monoszacharid-alapú koronaéterek szintézise, és királis fázistranszfer katalizátorként való alkalmazása enantioszelektív…”
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Green chemical approaches and tools in the development of environmentally friendly synthetic methods by Keglevich, György, Kerényi, Andrea, Sipos, Melinda, Ujj, Viktória, Makó, Attila, Csontos, István, Novák, Tibor, Bakó, Péter, Greiner, István

“…Addressing the recommendations of the 12 basic lows of green chemistry, the microwave technique was utilized in phospha-Mannich, Diels-Alder and inverse Wittig…”
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Synthesis of chiral pyridino-15-crown-5 type ligands containing α-D-hexapyranoside unit and their application in asymmetric synthesis by Attila Makó, Péter Bakó, Áron Szöllősy, Tibor Bakó, Csaba Peltz, Péter Keglevich

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