Search Results - "Mak, Tin"
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Discovery of a Natural Product That Binds to the Mycobacterium tuberculosis Protein Rv1466 Using Native Mass Spectrometry
Published in Molecules (Basel, Switzerland) (21-05-2020)“…Elucidation of the mechanism of action of compounds with cellular bioactivity is important for progressing compounds into future drug development. In recent…”
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A Phenotarget Approach for Identifying an Alkaloid Interacting with the Tuberculosis Protein Rv1466
Published in Marine drugs (05-03-2020)“…In recent years, there has been a revival of interest in phenotypic-based drug discovery (PDD) due to target-based drug discovery (TDD) falling below…”
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How Graduate-student or Recent Graduate Psychotherapists Experience and Manage Errors in Psychotherapy
Published in Counselling psychology quarterly (03-04-2022)“…We explored how graduate-student/recent graduate psychotherapists managed errors committed in psychotherapy, using consensual qualitative research (CQR) to…”
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Discovery of Anti-SARS-CoV‑2 Nsp9 Binders from Natural Products by a Native Mass Spectrometry Approach
Published in Journal of natural products (Washington, D.C.) (22-12-2023)“…The search for effective antiviral agents against SARS-CoV-2 remains a critical global endeavor. In this study, we focused on the viral nucleocapsid protein…”
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Development of an HPLC-based guanosine monophosphate kinase assay and application to Plasmodium vivax guanylate kinase
Published in Analytical biochemistry (15-06-2019)“…The development of a high-performance liquid chromatography (HPLC)-based method, for guanosine monophosphate kinase activity assays, is presented. The method…”
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Collision-Induced Affinity Selection Mass Spectrometry for Identification of Ligands
Published in ACS bio & med chem au (19-10-2022)“…Hyphenated mass spectrometry has been used to identify ligands binding to proteins. It involves mixing protein and compounds, separation of protein–ligand…”
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Immediacy in Supervision: Supervisees' Perspectives on Positive and Negative Events
Published in Journal of psychotherapy integration (01-09-2022)“…Eight mental health graduate student participants were interviewed regarding their positive and/or negative experiences of immediacy (IM) in supervision. Data…”
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Fragment-Based Screening of a Natural Product Library against 62 Potential Malaria Drug Targets Employing Native Mass Spectrometry
Published in ACS infectious diseases (13-04-2018)“…Natural products are well known for their biological relevance, high degree of three-dimensionality, and access to areas of largely unexplored chemical space…”
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