Search Results - "Mak, Nai‐Ki"

Proteomic analysis of exosomes from nasopharyngeal carcinoma cell identifies intercellular transfer of angiogenic proteins by Chan, Yuk‐Kit, Zhang, Huoming, Liu, Pei, Tsao, Sai‐Wah, Lung, Maria Li, Mak, Nai‐Ki, Ngok‐Shun Wong, Ricky, Ying‐Kit Yue, Patrick

“…Exosomes, a group of secreted extracellular nanovesicles containing genetic materials and signaling molecules, play a critical role in intercellular…”
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Tryptanthrin inhibits angiogenesis by targeting the VEGFR2-mediated ERK1/2 signalling pathway by Liao, Xuemei, Zhou, Xuelin, Mak, Nai-ki, Leung, Kwok-nam

“…Angiogenesis is a key step for tumour growth and metastasis, and anti-angiogenesis has been proposed as an important strategy for cancer therapy. Tryptanthrin…”
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CDK5RAP2 is a Wnt target gene and promotes stemness and progression of oral squamous cell carcinoma by Shen, Yuehong, Chen, Yuling, Lin, Yuntao, Li, Yicun, Liu, Pengfei, Zhang, Biru, Wang, Yufan, Chan, King-Chi, Mak, Nai-Ki, Kahn, Michael, Qi, Robert Z., Yang, Hongyu

“…In oral squamous cell carcinoma (OSCC), a highly aggressive and frequently lethal malignancy, the role and action mechanism of the microtubule regulatory…”
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Two-photon fluorescence probes for imaging of mitochondria and lysosomes by Yang, Wanggui, Chan, Pui Shan, Chan, Miu Shan, Li, King Fai, Lo, Pik Kwan, Mak, Nai Ki, Cheah, Kok Wai, Wong, Man Shing

“…Novel biocompatible cyanines show not only a very large two-photon cross-section of up to 5130 GM at 910 nm in aqueous medium for high-contrast and -brightness…”
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A red-light-activated sulfonamide porphycene for highly efficient photodynamic therapy against hypoxic tumor by Wang, Yuzhi, Pan, Zhaohai, Cheng, Xiao-Lan, Zhang, Kai, Zhang, Xin, Qin, Yao, Fan, Jiaojiao, Yan, Ting, Han, Tao, Shiu, Kwok Keung, Hau, Sam Chun-Kit, Mak, Nai-Ki, Kwong, Daniel W.J., Liu, Xiaona, Li, Minjing, Deng, Guowei, Zheng, Qiusheng, Lu, Jun, Li, Defang

“…Photodynamic therapy (PDT) is an emerging alternative cancer treatment modality that utilizes photo-sensitivity to cause cell death upon photo-irradiation…”
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Role of miR-96/EVI1/miR-449a Axis in the Nasopharyngeal Carcinoma Cell Migration and Tumor Sphere Formation by Chan, Lai-Sheung, Lung, Hong-Lok, Ngan, Roger Kai-Cheong, Lee, Anne Wing-Mui, Tsao, Sai Wah, Lo, Kwok-Wai, Kahn, Michael, Lung, Maria Li, Wieser, Rotraud, Mak, Nai-Ki

“…The Wnt signaling pathway is one of the major signaling pathways used by cancer stem cells (CSC). Ecotropic Viral Integration Site 1 (EVI1) has recently been…”
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The Wnt modulator ICG‑001 mediates the inhibition of nasopharyngeal carcinoma cell migration in vitro via the miR‑150/CD44 axis by Chan, Lai-Sheung, Man, On-Ying, Kwok, Hoi-Hin, Chen, Luo, Chan, King-Chi, Lung, Hong-Lok, Ngan, Roger Kai-Cheong, Wong, Ricky Ngok-Shun, Lo, Kwok-Wai, Lee, Anne Wing-Mui, Tsao, George Sai-Wah, Kahn, Michael, Lung, Maria Li, Mak, Nai-Ki

“…The Wnt signaling pathway is known to serve an important role in the control of cell migration. The present study analyzed the mechanisms underlying the…”
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Two-photon induced luminescence, singlet oxygen generation, cellular uptake and photocytotoxic properties of amphiphilic Ru(II) polypyridyl-porphyrin conjugates as potential bifunctional photodynamic therapeutic agents by Zhang, JingXiang, Wong, Ka-Leung, Wong, Wai-Kwok, Mak, Nai-Ki, Kwong, Daniel W J, Tam, Hoi-Lam

“…Two Ru(II) polypyridyl-porphyrin and Zn(II) porphyrin conjugates (Ru-L and Ru-Zn-L) have been synthesized and their photophysical properties studied. The two…”
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Lanthanide-Based Peptide-Directed Visible/Near-Infrared Imaging and Inhibition of LMP1 by Chau, Ho-Fai, Wu, Yue, Fok, Wan-Yiu, Thor, Waygen, Cho, William Chi-Shing, Ma, Ping'an, Lin, Jun, Mak, Nai-Ki, Bünzli, Jean-Claude G, Jiang, Lijun, Long, Nicholas J, Lung, Hong Lok, Wong, Ka-Leung

“…A lanthanide-based peptide-directed bioprobe (Ln = Eu or Yb) is designed as an impressive example of a small molecule-based dual-functional probe for the EBV…”
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Role of MIF/CXCL8/CXCR2 signaling in the growth of nasopharyngeal carcinoma tumor spheres by Lo, Ming-Chu, Yip, Tak-Chun, Ngan, Kai-Cheong, Cheng, Wai-Wai, Law, Chun-Key, Chan, Pui-Shan, Chan, King-Chi, Wong, Chris Kong-Chu, Wong, Ricky Ngok-Shun, Lo, Kwok-Wai, Ng, Wai-Tong, Lee, Wing-Mui, Tsao, Sai-Wah, Kwong, Lai-Wan, Lung, Maria Li, Mak, Nai-Ki

“…Highlights • CXCL8 transcripts are highly expressed in the NPC tissues. • MIF/CXCL8/CXCR2 signaling is involved in the in vitro growth of EBV-positive NPC…”
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Modulatory Effects and Action Mechanisms of Tryptanthrin on Murine Myeloid Leukemia Cells by Chan, Hoi-Ling, Yip, Hon-Yan, Mak, Nai-Ki, Leung, Kwok-Nam

“…Leukemia is the disorder of hematopoietic cell development and is characterized by an uncoupling of cell proliferation and differentiation. There is a pressing…”
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Quantum Dot-mediated Photoproduction of Reactive Oxygen Species for Cancer Cell Annihilation by Chen, Ji-Yao, Lee, Yee-Man, Zhao, Dan, Mak, Nai-Ki, Wong, Ricky Ngok-Shun, Chan, Wing-Hong, Cheung, Nai-Ho

“…While semiconductor quantum dots produce little singlet oxygen, they may undergo Type I photoreactions to produce other reactive oxygen species (ROS) to kill…”
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EBNA1-targeted probe for the imaging and growth inhibition of tumours associated with the Epstein–Barr virus by Jiang, Lijun, Lan, Rongfeng, Huang, Tao, Chan, Chi-Fai, Li, Hongguang, Lear, Sam, Zong, Jingyi, Wong, Wing-Yan, Muk-Lan Lee, Magnolia, Dow Chan, Brandon, Chan, Wai-Lun, Lo, Wai-Sum, Mak, Nai-Ki, Li Lung, Maria, Lok Lung, Hong, Wah Tsao, Sai, Taylor, Graham S., Bian, Zhao-Xiang, Tai, William C. S., Law, Ga-Lai, Wong, Wing-Tak, Cobb, Steven L., Wong, Ka-Leung

“…Epstein–Barr nuclear antigen 1 (EBNA1), a dimeric oncoprotein of the Epstein–Barr virus (EBV), is essential for both viral-genome maintenance and the survival…”
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Inhibition of RANTES expression by indirubin in influenza virus-infected human bronchial epithelial cells by Mak, Nai-Ki, Leung, Chung-Yee, Wei, Xiao-Yi, Shen, Xiao-Ling, Wong, Ricky Ngok-Shun, Leung, Kwok-Nam, Fung, Ming-Chiu

“…The human bronchial epithelial cells are the primary sites of influenza virus infection. In this study, the effect of indirubin on the expression of the…”
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Targeted inhibition of the EGFR pathways enhances Zn-BC-AM PDT-induced apoptosis in well-differentiated nasopharyngeal carcinoma cells by Koon, Ho-Kee, Chan, Pui-Shan, Wong, Ricky Ngok-Shun, Wu, Zhen-Guo, Lung, Maria Li, Chang, Chi-Kwong, Mak, Nai-Ki

“…Epidermal growth factor receptor (EGFR), a receptor often expressed in nasopharyngeal carcinoma (NPC) cells, is one of the recently identified molecular…”
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Targeting Epstein-Barr Virus in Nasopharyngeal Carcinoma by Hau, Pok Man, Lung, Hong Lok, Wu, Man, Tsang, Chi Man, Wong, Ka-Leung, Mak, Nai Ki, Lo, Kwok Wai

“…Nasopharyngeal carcinoma (NPC) is consistently associated with Epstein-Barr virus (EBV) infection in regions in which it is endemic, including Southern China…”
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EBNA1-targeted inhibitors: Novel approaches for the treatment of Epstein-Barr virus-associated cancers by Jiang, Lijun, Xie, Chen, Lung, Hong Lok, Lo, Kwok Wai, Law, Ga-Lai, Mak, Nai-Ki, Wong, Ka-Leung

“…Epstein-Barr virus (EBV) infects more than 90% of humans worldwide and establishes lifelong latent infection in the hosts. It is closely associated with…”
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Role of MicroRNA-214 in ginsenoside-Rg1-induced angiogenesis by CHAN, Lai-Sheung, YUE, Patrick Ying-Kit, MAK, Nai-Ki, WONG, Ricky Ngok-Shun

“…MicroRNAs (miRNAs) are small non-coding RNAs that act as post-transcriptional gene modulators. Ginsenoside-Rg1, one of the active components of ginseng, has…”
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Comparative Studies of the Cellular Uptake, Subcellular Localization, and Cytotoxic and Phototoxic Antitumor Properties of Ruthenium(II)–Porphyrin Conjugates with Different Linkers by Zhang, Jing-Xiang, Zhou, Jun-Wei, Chan, Chi-Fai, Lau, Terrence Chi-Kong, Kwong, Daniel W. J, Tam, Hoi-Lam, Mak, Nai-Ki, Wong, Ka-Leung, Wong, Wai-Kwok

“…Six water-soluble free-base porphyrin-Ru(II) conjugates, 1–3, and Zn(II) porphyrin-Ru(II) conjugates, 4–6, with different linkers between the hydrophobic…”
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Role of G3BP1 in glucocorticoid receptor-mediated microRNA-15b and microRNA-23a biogenesis in endothelial cells by Kwok, Hoi-Hin, Poon, Po-Ying, Mak, Kylie Hin-Man, Zhang, Lin-Yao, Liu, Pei, Zhang, Huoming, Mak, Nai-Ki, Yue, Patrick Ying-Kit, Wong, Ricky Ngok-Shun

“…MicroRNAs (miRNAs) are a family of non-coding RNAs that play crucial roles in regulating various normal cellular responses. Recent studies revealed that the…”
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