Search Results - "Mak, Marvin S. H."
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Advance of sporadic Alzheimer's disease animal models
Published in Medicinal research reviews (01-01-2020)“…Alzheimer's disease (AD), the most common form of dementia, is a progressive neurodegenerative disease. In the past decades, numbers of promising drug…”
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Dimeric Tacrine(10)-hupyridone as a Multitarget-Directed Ligand To Treat Alzheimer’s Disease
Published in ACS chemical neuroscience (07-07-2021)“…Alzheimer’s disease (AD) is a neurodegenerative disorder with multiple pathological features. Therefore, a multitarget-directed ligands (MTDLs) strategy has…”
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A Chinese herbal decoction, reformulated from Kai-Xin-San, relieves the depression-like symptoms in stressed rats and induces neurogenesis in cultured neurons
Published in Scientific reports (22-07-2016)“…Kai-Xin-San (KXS), a Chinese herbal decoction for anti-depression, is a combination of paired-herbs, i.e. Ginseng Radix et Rhizoma (GR)-Polygalae Radix (PR)…”
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Acrolein, an endogenous aldehyde induces Alzheimer's disease-like pathologies in mice: A new sporadic AD animal model
Published in Pharmacological research (01-01-2022)“…Alzheimer’s disease (AD) is a common neurodegenerative disease that mainly affects elderly people. However, the translational research of AD is frustrating,…”
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Design, Synthesis, and Biological Evaluation of Novel Multifunctional Rolipram–Tranilast Hybrids As Potential Treatment for Traumatic Brain Injury
Published in ACS chemical neuroscience (05-08-2020)“…Traumatic brain injury (TBI) is a prevalent public healthcare concern frequently instigated by mechanical shock, traffic, or violence incidents, leading to…”
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