Search Results - "Mak, Ki"

Basement Membrane Type IV Collagen and Laminin: An Overview of Their Biology and Value as Fibrosis Biomarkers of Liver Disease by Mak, Ki M., Mei, Rena

“…ABSTRACT Basement membranes provide structural support to epithelium, endothelium, muscles, fat cells, Schwann cells, and axons. Basement membranes are…”
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Lipopolysaccharide, arbiter of the gut-liver axis, modulates hepatic cell pathophysiology in alcoholism by Mak, Ki M, Shekhar, Aditya C

“…Over the last four decades, clinical research and experimental studies have established that lipopolysaccharide (LPS)-a component of the outer membrane of…”
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A Low-Power Fast-Transient 90-nm Low-Dropout Regulator With Multiple Small-Gain Stages by Ho, Marco, Ka Nang Leung, Ki-Leung Mak

“…A power-efficient 90-nm low-dropout regulator (LDO) with multiple small-gain stages is proposed in this paper. The proposed channel-resistance-insensitive…”
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Soybean polyenylphosphatidylcholine (PPC) is beneficial in liver and extrahepatic tissue injury: An update in experimental research by Mak, Ki M., Shekhar, Aditya C.

“…Polyenylphosphatidylcholine (PPC) is a purified polyunsaturated phosphatidylcholine extract of soybeans. This article updates PPC's beneficial effects on…”
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Type V Collagen in Health, Disease, and Fibrosis by Mak, Ki M., Png, Chien Yi M., Lee, Danielle J.

“…ABSTRACT Type V collagen (COLV) is a regulatory fibril‐forming collagen. It has at least three different molecular isoforms—α1(V)2α2(V), α1(V)3, and…”
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Lipid droplets, the Holy Grail of hepatic stellate cells: In health and hepatic fibrosis by Mak, Ki M., Wu, Catherine, Cheng, Christopher P.

“…Lipid droplets (LDs) are distinct morphological markers of hepatic stellate cells (HSCs). They are composed of a core of predominantly retinyl esters and…”
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Alcohol‐associated capillarization of sinusoids: A critique since the discovery by Schaffner and Popper in 1963 by Mak, Ki M., Kee, Dustin, Shin, Da Wi

“…This article reviews the literature on capillarization of hepatic sinusoids since its discovery in 1963. Liver sinusoidal endothelial cells are uniquely…”
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Proteomic analysis of exosomes from nasopharyngeal carcinoma cell identifies intercellular transfer of angiogenic proteins by Chan, Yuk‐Kit, Zhang, Huoming, Liu, Pei, Tsao, Sai‐Wah, Lung, Maria Li, Mak, Nai‐Ki, Ngok‐Shun Wong, Ricky, Ying‐Kit Yue, Patrick

“…Exosomes, a group of secreted extracellular nanovesicles containing genetic materials and signaling molecules, play a critical role in intercellular…”
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Hepatic sinusoids versus central veins: Structures, markers, angiocrines, and roles in liver regeneration and homeostasis by Mak, Ki M., Shin, Da Wi

“…The blood circulates through the hepatic sinusoids delivering nutrients and oxygen to the liver parenchyma and drains into the hepatic central vein, yet the…”
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A Single-Inductor Multiple-Output Auto-Buck-Boost DC-DC Converter With Autophase Allocation by Yanqi Zheng, Ho, Marco, Jianping Guo, Ki-Leung Mak, Ka Nang Leung

“…A single-inductor multiple-output (SIMO) converter with auto-buck-boost feature is presented in this paper. A seamless auto-buck-boost scheme for SIMO dc-dc…”
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A review of hepatic fibrosis‐associated histopathology in aged cadavers by Mak, Ki M., Kee, Dustin, Cheng, Christopher P.

“…This article reviews hepatic fibrosis‐associated histopathology of aged cadavers (mean age 82 years). A study of 68 livers identified steatosis in 35.5%,…”
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Two-photon fluorescence probes for imaging of mitochondria and lysosomes by Yang, Wanggui, Chan, Pui Shan, Chan, Miu Shan, Li, King Fai, Lo, Pik Kwan, Mak, Nai Ki, Cheah, Kok Wai, Wong, Man Shing

“…Novel biocompatible cyanines show not only a very large two-photon cross-section of up to 5130 GM at 910 nm in aqueous medium for high-contrast and -brightness…”
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Tryptanthrin inhibits angiogenesis by targeting the VEGFR2-mediated ERK1/2 signalling pathway by Liao, Xuemei, Zhou, Xuelin, Mak, Nai-ki, Leung, Kwok-nam

“…Angiogenesis is a key step for tumour growth and metastasis, and anti-angiogenesis has been proposed as an important strategy for cancer therapy. Tryptanthrin…”
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CDK5RAP2 is a Wnt target gene and promotes stemness and progression of oral squamous cell carcinoma by Shen, Yuehong, Chen, Yuling, Lin, Yuntao, Li, Yicun, Liu, Pengfei, Zhang, Biru, Wang, Yufan, Chan, King-Chi, Mak, Nai-Ki, Kahn, Michael, Qi, Robert Z., Yang, Hongyu

“…In oral squamous cell carcinoma (OSCC), a highly aggressive and frequently lethal malignancy, the role and action mechanism of the microtubule regulatory…”
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The Hepatic Central Vein: Structure, Fibrosis, and Role in Liver Biology by Mak, Ki M., Png, C. Y. Maximilian

“…ABSTRACT The hepatic central vein is a primary source of Wnt2, Wnt9b, and R‐spondin3. These angiocrines activate ß‐catenin signaling to regulate hepatic…”
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A red-light-activated sulfonamide porphycene for highly efficient photodynamic therapy against hypoxic tumor by Wang, Yuzhi, Pan, Zhaohai, Cheng, Xiao-Lan, Zhang, Kai, Zhang, Xin, Qin, Yao, Fan, Jiaojiao, Yan, Ting, Han, Tao, Shiu, Kwok Keung, Hau, Sam Chun-Kit, Mak, Nai-Ki, Kwong, Daniel W.J., Liu, Xiaona, Li, Minjing, Deng, Guowei, Zheng, Qiusheng, Lu, Jun, Li, Defang

“…Photodynamic therapy (PDT) is an emerging alternative cancer treatment modality that utilizes photo-sensitivity to cause cell death upon photo-irradiation…”
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Downregulation of hepatic stellate cell activation by retinol and palmitate mediated by adipose differentiation-related protein (ADRP) by Lee, Ting Fang, Mak, Ki M., Rackovsky, Ori, Lin, Yun-Lian, Kwong, Allison J., Loke, Johnny C., Friedman, Scott L.

“…Hepatic stellate cells (HSCs) store retinoids and triacylglycerols in cytoplasmic lipid droplets. Two prominent features of HSC activation in liver fibrosis…”
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Role of miR-96/EVI1/miR-449a Axis in the Nasopharyngeal Carcinoma Cell Migration and Tumor Sphere Formation by Chan, Lai-Sheung, Lung, Hong-Lok, Ngan, Roger Kai-Cheong, Lee, Anne Wing-Mui, Tsao, Sai Wah, Lo, Kwok-Wai, Kahn, Michael, Lung, Maria Li, Wieser, Rotraud, Mak, Nai-Ki

“…The Wnt signaling pathway is one of the major signaling pathways used by cancer stem cells (CSC). Ecotropic Viral Integration Site 1 (EVI1) has recently been…”
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Codistribution of Collagen Type IV and Laminin in Liver Fibrosis of Elderly Cadavers: Immunohistochemical Marker of Perisinusoidal Basement Membrane Formation by Mak, Ki M., Chen, Lucy L., Lee, Ting‐Fang

“…ABSTRACT Liver sinusoids are lined by a fenestrated endothelium that lacks a basement membrane. Formation of perisinusoidal basement membranes beneath the…”
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Two-photon induced luminescence, singlet oxygen generation, cellular uptake and photocytotoxic properties of amphiphilic Ru(II) polypyridyl-porphyrin conjugates as potential bifunctional photodynamic therapeutic agents by Zhang, JingXiang, Wong, Ka-Leung, Wong, Wai-Kwok, Mak, Nai-Ki, Kwong, Daniel W J, Tam, Hoi-Lam

“…Two Ru(II) polypyridyl-porphyrin and Zn(II) porphyrin conjugates (Ru-L and Ru-Zn-L) have been synthesized and their photophysical properties studied. The two…”
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