Search Results - "Major, L."
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Tablet use in schools: a critical review of the evidence for learning outcomes
Published in Journal of computer assisted learning (01-04-2016)“…The increased popularity of tablets in general has led to uptake in education. We critically review the literature reporting use of tablets by primary and…”
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2
An eggshell-localised annexin plays a key role in the coordination of the life cycle of a plant-parasitic nematode with its host
Published in PLoS pathogens (13-02-2023)“…Host-specific plant pathogens must coordinate their life cycles with the availability of a host plant. Although this is frequently achieved through a response…”
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3
Nonlinear dynamics of a bistable system impacting a sinusoidally vibrating shaker
Published in Nonlinear dynamics (01-12-2022)“…Bistable systems have seen significant interest in recent years, in applications ranging from energy harvesting, impact mitigation, and aerospace, to precision…”
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4
Hydrogen Peroxide Activated Matrix Metalloproteinase Inhibitors: A Prodrug Approach
Published in Angewandte Chemie (International ed.) (10-09-2010)“…Doing double duty: A metalloproteinase inhibitor that can be activated by reactive oxygen species (ROS) has been designed to protect the blood‐brain barrier…”
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5
To bind zinc or not to bind zinc: An examination of innovative approaches to improved metalloproteinase inhibition
Published in Biochimica et biophysica acta (2010)“…This short review highlights some recent advances in matrix metalloproteinase inhibitor (MMPi) design and development. Three distinct approaches to improved…”
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6
HDAC11 inhibition triggers bimodal thermogenic pathways to circumvent adipocyte catecholamine resistance
Published in The Journal of clinical investigation (01-10-2023)“…Stimulation of adipocyte β-adrenergic receptors (β-ARs) induces expression of uncoupling protein 1 (UCP1), promoting nonshivering thermogenesis. Association of…”
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7
The incredible shrinking puffin: Decreasing size and increasing proportional bill size of Atlantic puffins nesting at Machias Seal Island
Published in PloS one (17-01-2024)“…Climate change imposes physiological constraints on organisms particularly through changing thermoregulatory requirements. Bergmann's and Allen's rules suggest…”
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Wear mechanisms description in nanoscale by SEM/TEM of multilayer Zr/ZrN coatings in dependence on phases ratio
Published in Journal of microscopy (Oxford) (01-01-2023)“…As a result of loading with an external force during the wear process, coating deforms uniformly. After a certain limit load is exceeded, coating deformation…”
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9
Classroom dialogue and digital technologies: A scoping review
Published in Education and information technologies (01-09-2018)“…This article presents a systematic scoping review of the literature focusing on interactions between classroom dialogue and digital technology. The first…”
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10
Forkhead Box M1B Transcriptional Activity Requires Binding of Cdk-Cyclin Complexes for Phosphorylation-Dependent Recruitment of p300/CBP Coactivators
Published in Molecular and Cellular Biology (01-04-2004)“…Article Usage Stats Services MCB Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley…”
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11
synthesis and in vitro testing of a zinc-activated MRI contrast agent
Published in Proceedings of the National Academy of Sciences - PNAS (28-08-2007)“…Zinc(II) plays a vital role in normal cellular function as an essential component of numerous enzymes, transcription factors, and synaptic vesicles. While zinc…”
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Forkhead Box M1 Regulates the Transcriptional Network of Genes Essential for Mitotic Progression and Genes Encoding the SCF (Skp2-Cks1) Ubiquitin Ligase
Published in Molecular and Cellular Biology (01-12-2005)“…Article Usage Stats Services MCB Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley…”
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13
HDAC6 modulates myofibril stiffness and diastolic function of the heart
Published in The Journal of clinical investigation (16-05-2022)“…Passive stiffness of the heart is determined largely by extracellular matrix and titin, which functions as a molecular spring within sarcomeres. Titin…”
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14
Reversible lysine fatty acylation of an anchoring protein mediates adipocyte adrenergic signaling
Published in Proceedings of the National Academy of Sciences - PNAS (15-02-2022)“…-myristoylation on glycine is an irreversible modification that has long been recognized to govern protein localization and function. In contrast, the…”
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15
Investigation of self-immolative linkers in the design of hydrogen peroxide activated metalloprotein inhibitors
Published in Chemical communications (Cambridge, England) (28-07-2011)“…A series of self-immolative boronic ester protected methyl salicylates and metal-binding groups with various linking strategies have been investigated for…”
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Financial costs of conducting science in the Arctic: examples from seabird research
Published in Arctic science (01-12-2018)“…Research in remote locations is more expensive than similar activities at sites with easier access, but these costs have rarely been compared. Using examples…”
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The Wear Mechanisms Description Of Multilayer Coatings, Performed By Transmission Electron Microscopy – An Overview Of The Own Research Work
Published in Archives of metallurgy and materials (01-09-2015)“…The aim of the presented paper was to describe the wear mechanisms operating at the small length scale in multilayer coatings subjected to a mechanical…”
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18
Laser modification of the materials surface layer – a review paper
Published in Bulletin of the Polish Academy of Sciences. Technical sciences (01-12-2012)“…The state of laser processing in surface materials modification in Poland is reported, based on own experience, coworkers and coauthors results, as well the…”
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School-based Simulated Internships to support dialogic collaboration and authentic links with the world of work: a design-based research study
Published in Irish educational studies (02-01-2022)“…Employers often complain that students leave school unequipped with the real-world skills needed, including problem-solving, teamwork and effective…”
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Novel Benzothiazole-based Ureas as 17β-HSD10 Inhibitors, A Potential Alzheimer's Disease Treatment
Published in Molecules (Basel, Switzerland) (29-07-2019)“…It has long been established that mitochondrial dysfunction in Alzheimer's disease (AD) patients can trigger pathological changes in cell metabolism by…”
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