Search Results - "Majmudar, Parth R."

KLF4 defines the efficacy of the epidermal growth factor receptor inhibitor, erlotinib, in triple-negative breast cancer cells by repressing the EGFR gene by Roberts, Melyssa S, Anstine, Lindsey J, Finke, Viviane S, Bryson, Benjamin L, Webb, Bryan M, Weber-Bonk, Kristen L, Seachrist, Darcie D, Majmudar, Parth R, Keri, Ruth A

“…Triple-negative breast cancer (TNBC) is characterized by high rates of recurrence and poor overall survival. This is due, in part, to a deficiency of targeted…”
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Targeting YES1 Disrupts Mitotic Fidelity and Potentiates the Response to Taxanes in Triple-Negative Breast Cancer by Piemonte, Katrina M, Ingles, Natasha N, Weber Bonk, Kristen L, Valentine, Mitchell J, Majmudar, Parth R, Singh, Salendra, Keri, Ruth A

“…Clinical trials examining broad-spectrum Src family kinase (SFK) inhibitors revealed significant dose-limiting toxicities, preventing advancement for solid…”
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Disruption of CDK7 signaling leads to catastrophic chromosomal instability coupled with a loss of condensin-mediated chromatin compaction by Piemonte, Katrina M., Webb, Bryan M., Bobbitt, Jessica R., Majmudar, Parth R., Cuellar-Vite, Leslie, Bryson, Benjamin L., Latina, Nicholas C., Seachrist, Darcie D., Keri, Ruth A.

“…Chromatin organization is highly dynamic and modulates DNA replication, transcription, and chromosome segregation. Condensin is essential for chromosome…”
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TLE3 Sustains Luminal Breast Cancer Lineage Fidelity to Suppress Metastasis by Anstine, Lindsey J, Majmudar, Parth R, Aponte, Amy, Singh, Salendra, Zhao, Ran, Weber-Bonk, Kristen L, Abdul-Karim, Fadi W, Valentine, Mitchell, Seachrist, Darcie D, Grennel-Nickelson, Katelyn E, Cuellar-Vite, Leslie, Sizemore, Gina M, Sizemore, Steven T, Webb, Bryan M, Thompson, Cheryl L, Keri, Ruth A

“…Breast cancer subtypes and their phenotypes parallel different stages of the mammary epithelial cell developmental hierarchy. Discovering mechanisms that…”
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Differences in Endothelin B Receptor Isoforms Expression and Function in Breast Cancer Cells by Halaka, Meena, Hired, Zuhaila A, Rutledge, Grace E, Hedgepath, Carly M, Anderson, Michael P, St John, Haley, Do, Jessica M, Majmudar, Parth R, Walker, Caleb, Alawawdeh, Asma, Stephen, Hannah M, Reagor, Caleb C, Adereti, Jeanette, Jamison, Kiara, Iglesias, Katherine P, Kirmani, Khadija Z, Conway, Rebecca E

“…The endothelins and their receptors are best known for their regulation of the vascular system. Their widespread expression in epithelial cells and their…”
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