Search Results - "Majik, Mahesh S"

Decreased expression of synapse-related genes and loss of synapses in major depressive disorder by Kang, Hyo Jung, Voleti, Bhavya, Hajszan, Tibor, Rajkowska, Grazyna, Stockmeier, Craig A, Licznerski, Pawel, Lepack, Ashley, Majik, Mahesh S, Jeong, Lak Shin, Banasr, Mounira, Son, Hyeon, Duman, Ronald S

“…Ronald Duman and colleagues report that synapse number is reduced in subjects with major depressive disorder. This is associated with decreased expression of…”
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Fluorescence Turn-on Chemosensor for the Detection of Dissolved CO2 Based on Ion-Induced Aggregation of Tetraphenylethylene Derivative by Khandare, Dipratn G, Joshi, Hrishikesh, Banerjee, Mainak, Majik, Mahesh S, Chatterjee, Amrita

“…Herein, a sensitive fluorimetric assay for dissolved carbon dioxide (dCO2) was developed by using ion-induced self-assembly of a tetraphenylethylene derivative…”
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Next generation biofilm inhibitors for Pseudomonas aeruginosa: Synthesis and rational design approaches by Majik, Mahesh S, Parvatkar, Prakash T

“…The bacterial biofilms and the emergence of multiple drug resistance have become a major threat for current medical treatment of nosocomial infections. It has…”
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Total Synthesis of (−)- and (+)-Tedanalactam by Majik, Mahesh S, Parameswaran, Perunninakulath S, Tilve, Santosh G

“…The first stereoselective route providing access to both enantiomers of tedanalactam, a naturally occurring piperidone, has been developed. The stereogenic…”
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Synthetic access to thiolane-based therapeutics and biological activity studies by Rodrigues, Lima, Tilve, Santosh G., Majik, Mahesh S.

“…Secondary metabolites isolated from bioactive extracts of natural sources iteratively pioneer the research in drug discovery. Modern medicine is often inspired…”
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Next generation quorum sensing inhibitors: Accounts on structure activity relationship studies and biological activities by Majik, Mahesh S., Gawas, Umesh B., Mandrekar, Vinod K.

“…[Display omitted] Bacterial resistance is a growing threat which represents major scourge throughout the world. The suitable way to control the present…”
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Structure–Activity Relationships of Truncated C2- or C8-Substituted Adenosine Derivatives as Dual Acting A2A and A3 Adenosine Receptor Ligands by Hou, Xiyan, Majik, Mahesh S, Kim, Kyunglim, Pyee, Yuna, Lee, Yoonji, Alexander, Varughese, Chung, Hwa-Jin, Lee, Hyuk Woo, Chandra, Girish, Lee, Jin Hee, Park, Seul-gi, Choi, Won Jun, Kim, Hea Ok, Phan, Khai, Gao, Zhan-Guo, Jacobson, Kenneth A, Choi, Sun, Lee, Sang Kook, Jeong, Lak Shin

“…Truncated N 6-substituted-4′-oxo- and 4′-thioadenosine derivatives with C2 or C8 substitution were studied as dual acting A2A and A3 adenosine receptor (AR)…”
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Design and synthesis of marine natural product-based 1H-indole-2,3-dione scaffold as a new antifouling/antibacterial agent against fouling bacteria by Majik, Mahesh S., Rodrigues, Cheryl, Mascarenhas, Stacey, D’Souza, Lisette

“…[Display omitted] •Isatin is antifungal and ecologically defensive marine natural product tested for SAR study.•An efficient synthesis was achieved using…”
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Synthesis of (R)-norbgugaine and its potential as quorum sensing inhibitor against Pseudomonas aeruginosa by Majik, Mahesh S., Naik, Deepak, Bhat, Chinmay, Tilve, Santosh, Tilvi, Supriya, D’Souza, Lisette

“…(R)-Bgugaine is a natural pyrrolidine alkaloid from Arisarum vulgare, which shows antifungal and antibacterial activity. In this Letter, we have accomplished…”
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Quick elucidation of cyclodepsipeptide sequence from sacoglossan Elysia grandifolia using electrospray ionisation-tandem mass spectrometry by Tilvi, Supriya, Devi, Prabha, Majik, Mahesh S

“…Butanol fraction of sacoglossan Elysia grandifolia was investigated for identifying peptides using electrospray ionisation-tandem mass spectrometry…”
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Evaluation of single and joint effect of metabolites isolated from marine sponges, Fasciospongia cavernosa and Axinella donnani on antimicrobial properties by Majik, Mahesh S, Shirodkar, Dipika, Rodrigues, Cheryl, D'Souza, Lisette, Tilvi, Supriya

“…The biochemical mechanisms that marine sponges have developed as a chemical defense to protect themselves against micro and subsequent macrobiofouling process…”
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Asymmetric Synthesis of (−)-6′-β-Fluoro-aristeromycin via Stereoselective Electrophilic Fluorination by Kim, Gyudong, Yoon, Ji-seong, Jarhad, Dnyandev B, Shin, Young Sup, Majik, Mahesh S, Mulamoottil, Varughese A, Hou, Xiyan, Qu, Shuhao, Park, Jiyong, Baik, Mu-Hyun, Jeong, Lak Shin

“…(−)-6′-β-Fluoro-aristeromycin (2), a potent inhibitor of S-adenosylhomocysteine (AdoHcy) hydrolase, has been synthesized via stereoselective electrophilic…”
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Stereoselective Synthesis of Fluoro-homoneplanocin A as a Potential Antiviral Agent by Chandra, Girish, Majik, Mahesh S, Lee, Ji Yee, Jeong, Lak Shin

“…Fluoro-homoneplanocin A (4) was synthesized from d-ribose, via the enyne ring-closing metathesis of 9, the stereoselective opening of epoxide 23a with…”
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Fluorocyclopentenyl-cytosine with Broad Spectrum and Potent Antitumor Activity by Choi, Won Jun, Chung, Hwa-Jin, Chandra, Girish, Alexander, Varughese, Zhao, Long Xuan, Lee, Hyuk Woo, Nayak, Akshata, Majik, Mahesh S, Kim, Hea Ok, Kim, Jin-Hee, Lee, Young B, Ahn, Chang H, Lee, Sang Kook, Jeong, Lak Shin

“…On the basis of the potent biological activity of cyclopentenyl-pyrimidines, fluorocyclopentenyl-pyrimidines were designed and synthesized from d-ribose. Among…”
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Quick Identification of Piperidine Alkaloid from Roots of Grewia nervosa and Their Glucosidase Inhibitory Activity by Meena, Surya N., Majik, Mahesh S., Ghadi, Sanjeev C., Tilve, Santosh G.

“…Grewia nervosa is a herbal plant used in traditional medicine for different purposes. Bioassay‐guided chemical fractionation of G. nervosa roots resulted in an…”
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Synthesis and photophysical characterization of quasi push–pull dicyanodibenzodioxins and their anti-tumor activity against glioma cell line C6 by Banerjee, Subhadeep, Chattopadhyay, Anjan, Banerjee, Arnab, Haridas, Meera, Saini, Praveen, Das, Moitreyi, Majik, Mahesh S., Maurya, Yogesh Kr

“…[Display omitted] Dibenzodioxins bearing multiple electron withdrawing groups were synthesized using a simple one-step methodology including examples of…”
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Tandem Wittig−Ene Reaction Approach to Kainic Acid by Majik, Mahesh S, Parameswaran, Peruninakulath S, Tilve, Santosh G

“…The first example of a tandem Wittig−intramolecular ene reaction approach and its application toward the synthesis of kainic acid is reported. The synthetic…”
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Intramolecular Wittig Reaction: A New Synthesis of (S)-Pyrrolam A by Majik, Mahesh S., Parameswaran, Perunninakulath S., Tilve, Santosh G.

“…A straightforward synthesis of (S)‐pyrrolam A is described. The synthesis involves in situ generation of the phosphorane 3, followed by an intramolecular…”
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Synthesis of (−)-elemoxide, a commercially important fragrance compound by Rodrigues, Lima, Majik, Mahesh S., Tilve, Santosh G., Wahidulla, Solimabi

“…[Display omitted] •An efficient four steps synthesis of a fragrant sesquiterpene oxide is reported.•Regioselective epoxidation with m-CPBA.•Regioselective…”
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2D NMR Studies of Bromotyrosine Alkaloid, Purpurealidin K from Marine Sponge Psammaplysilla purpurea by Tilvi, Supriya, Majik, Mahesh S.

“…Marine sponges of the order Verongida and related organisms are the richest source of bioactive bromotyrosine alkaloids. Purpurealidin K (1) along with…”
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