Search Results - "Majidpoor, Jamal"

Steps in metastasis: an updated review by Majidpoor, Jamal, Mortezaee, Keywan

“…Metastasis is the most complex and deadly event. Tumor-stromal interface is a place where invasion of tumor cells in the form of single-cell or collective…”
Get full text

Angiogenesis as a hallmark of solid tumors - clinical perspectives by Majidpoor, Jamal, Mortezaee, Keywan

“…Background Angiogenesis is a key and early step in tumorigenesis, and is known as a hallmark of solid tumors and a key promoter of tumor recurrence. Unlike…”
Get full text

Interleukin-6 in SARS-CoV-2 induced disease: Interactions and therapeutic applications by Majidpoor, Jamal, Mortezaee, Keywan

“…Interleukin-6 (IL-6) is a multi-tasking cytokine that represents high activity in patients with severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2)…”
Get full text

Key promoters of tumor hallmarks by Mortezaee, Keywan, Majidpoor, Jamal

“…Evolution of tumor hallmarks is a result of accommodation of tumor cells with their nearby milieu called tumor microenvironment (TME). Accommodation or…”
Get full text

Mechanisms of CD8+ T cell exclusion and dysfunction in cancer resistance to anti-PD-(L)1 by Mortezaee, Keywan, Majidpoor, Jamal

“…CD8+ T cells are the front-line defensive cells against cancer. Reduced infiltration and effector function of CD8+ T cells occurs in cancer and is contributed…”
Get full text

The current knowledge concerning solid cancer and therapy by Najafi, Masoud, Majidpoor, Jamal, Toolee, Heidar, Mortezaee, Keywan

“…Solid cancers comprise a large number of new cases and deaths from cancer each year globally. There are a number of strategies for addressing tumors raised…”
Get full text

Roles for macrophage-polarizing interleukins in cancer immunity and immunotherapy by Mortezaee, Keywan, Majidpoor, Jamal

“…Macrophages are the most abundant and one of the most critical cells of tumor immunity. They provide a bridge between innate and adaptive immunity through…”
Get full text

Cancer stem cells in immunoregulation and bypassing anti-checkpoint therapy by Rouzbahani, Elnaz, Majidpoor, Jamal, Najafi, Sajad, Mortezaee, Keywan

“…Tumor microenvironment (TME) takes critical roles in tumor resistance to immune checkpoint inhibitors (ICIs) including anti-programmed death-1 (PD-1) or…”
Get full text

(Im)maturity in Tumor Ecosystem by Mortezaee, Keywan, Majidpoor, Jamal

“…Tumors have special features that make them distinct from their normal counterparts. Immature cells in a tumor mass and their critical contributions to the…”
Get full text

CD8 + T Cells in SARS-CoV-2 Induced Disease and Cancer-Clinical Perspectives by Mortezaee, Keywan, Majidpoor, Jamal

“…Dysregulated innate and adaptive immunity is a sign of SARS-CoV-2-induced disease and cancer. CD8 T cells are important cells of the immune system. The cells…”
Get full text

Reinstating immunogenicity using bispecific anti-checkpoint/agent inhibitors by Mortezaee, Keywan, Majidpoor, Jamal

“…Immune checkpoint inhibitor (ICI) resistance demands for acquisition of novel strategies in order to broaden the therapeutic repertoire of advanced cancers…”
Get full text

Macrophage polarity in cancer: A review by Najafi, Masoud, Hashemi Goradel, Nasser, Farhood, Bagher, Salehi, Eniseh, Nashtaei, Maryam Shabani, Khanlarkhani, Neda, Khezri, Zahra, Majidpoor, Jamal, Abouzaripour, Morteza, Habibi, Mohsen, Kashani, Iraj Ragerdi, Mortezaee, Keywan

“…Macrophages are the most abundant cells within the tumor stroma displaying noticeable plasticity, which allows them to perform several functions within the…”
Get full text

Checkpoint inhibitor/interleukin‐based combination therapy of cancer by Mortezaee, Keywan, Majidpoor, Jamal

“…Background Immunotherapy using immune checkpoint inhibitors (ICIs) is the current focus in cancer immunotherapy. However, issues are raised in the area, as the…”
Get full text

Bypassing anti-PD-(L)1 therapy: Mechanisms and management strategies by Mortezaee, Keywan, Majidpoor, Jamal, Najafi, Sajad, Tasa, Davood

“…Resistance to immune checkpoint inhibitors (ICIs) is a major issue of the current era in cancer immunotherapy. Immune evasion is a multi-factorial event, which…”
Get full text

Cellular immune states in SARS-CoV-2-induced disease by Mortezaee, Keywan, Majidpoor, Jamal

“…The general immune state plays important roles against severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection. Cells of the immune system are…”
Get full text

The impact of hypoxia on tumor-mediated bypassing anti-PD-(L)1 therapy by Mortezaee, Keywan, Majidpoor, Jamal, Kharazinejad, Ebrahim

“…Extending the durability of response is the current focus in cancer immunotherapy with immune checkpoint inhibitors (ICIs). However, factors like…”
Get full text

An update on the role of miR-124 in the pathogenesis of human disorders by Ghafouri-Fard, Soudeh, Shoorei, Hamed, Bahroudi, Zahra, Abak, Atefe, Majidpoor, Jamal, Taheri, Mohammad

“…[Display omitted] MicroRNA-124 (miR-124) is a copious miRNA in the brain, but it is expressed in a wide range of human/animal tissues participating in the…”
Get full text

Regulatory role of microRNAs on PTEN signaling by Ghafouri-Fard, Soudeh, Abak, Atefe, Shoorei, Hamed, Mohaqiq, Mahdi, Majidpoor, Jamal, Sayad, Arezou, Taheri, Mohammad

“…Phosphatase and tensin homolog (PTEN) gene encodes a tumor suppressor protein which is altered in several malignancies. This protein is a negative regulator of…”
Get full text

The impact of oncolytic adenoviral therapy on the therapeutic efficacy of PD-1/PD-L1 blockade by Najafi, Sajad, Majidpoor, Jamal, Mortezaee, Keywan

“…Immunotherapy has revolutionized treatment of cancer during the last decades. Oncolytic virotherapy has also emerged as a strategy to fight against cancer…”
Get full text

Alternative immune checkpoints in immunoregulatory profile of cancer stem cells by Mortezaee, Keywan, Majidpoor, Jamal

“…Tumor-mediated bypass of immune checkpoint inhibitor (ICI) therapy with anti-programmed death-1 (PD-1), anti-programmed death-ligand 1 (PD-L1, also called…”
Get full text