Search Results - "Majidinia, Maryam"
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The roles of signaling pathways in bone repair and regeneration
Published in Journal of cellular physiology (01-04-2018)“…Regenerative medicine has sparked interest in potential strategies for bone repair. Bone defects are widespread and could be caused by trauma, congenital…”
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2
Breast tumor stroma: A driving force in the development of resistance to therapies
Published in Chemical biology & drug design (01-03-2017)“…Breast cancer is the most common cancer and the second leading cause of cancer‐related death in women worldwide. In spite of huge advancements in early…”
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3
RAS/MAPK signaling functions in oxidative stress, DNA damage response and cancer progression
Published in Journal of cellular physiology (01-09-2019)“…Mitogen‐activated protein kinase (MAPK) signaling pathways organize a great constitution network that regulates several physiological processes, like cell…”
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4
CRISPR/Cas9 technology as a potent molecular tool for gene therapy
Published in Journal of cellular physiology (01-08-2019)“…Clustered regularly interspaced short palindromic repeats/CRISPR‐associated nuclease 9 (CRISPR‐Cas9) is an RNA‐guided gene editing tool which offers several…”
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5
Melatonin: a pleiotropic hormone as a novel potent therapeutic candidate in arsenic toxicity
Published in Molecular biology reports (01-09-2021)“…Background Arsenic is a natural element which exists in the environment in inorganic and organic forms. In humans, the main reason for the toxicity of arsenic…”
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6
The Critical Function of microRNAs in Developing Resistance against 5- Fluorouracil in Cancer Cells
Published in Mini reviews in medicinal chemistry (01-01-2024)“…Although there have been significant advancements in cancer treatment, resistance and recurrence in patients make it one of the leading causes of death…”
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7
The roles of signaling pathways in liver repair and regeneration
Published in Journal of cellular physiology (01-09-2019)“…The liver has remarkable regeneration potency that restores liver mass and sustains body hemostasis. Liver regeneration through signaling pathways following…”
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8
Melatonin in regulation of inflammatory pathways in rheumatoid arthritis and osteoarthritis: involvement of circadian clock genes
Published in British journal of pharmacology (01-08-2018)“…Rheumatoid arthritis (RA) and osteoarthritis (OA) are the two most prevalent joint diseases. A such, they are important causes of pain and disability in a…”
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Combination of exercise training and l-arginine reverses aging process through suppression of oxidative stress, inflammation, and apoptosis in the rat heart
Published in Pflügers Archiv (01-02-2020)“…Aging-induced progressive decline of molecular and metabolic factors in the myocardium is suggested to be related with heart dysfunction and cardiovascular…”
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Unveiling the potential of FOXO3 in lung cancer: From molecular insights to therapeutic prospects
Published in Biomedicine & pharmacotherapy (01-07-2024)“…Lung cancer poses a significant challenge regarding molecular heterogeneity, as it encompasses a wide range of molecular alterations and cancer-related…”
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Therapeutic potential of polyphenols in cardiovascular diseases: Regulation of mTOR signaling pathway
Published in Pharmacological research (01-02-2020)“…[Display omitted] Cardiovascular diseases comprise of non-communicable disorders that involve the heart and/or blood vessels and have become the leading cause…”
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Ovarian cancer stem cell: A potential therapeutic target for overcoming multidrug resistance
Published in Journal of cellular physiology (01-04-2019)“…The cancer stem cell (CSC) model encompasses an advantageous paradigm that in recent decades provides a better elucidation for many important biological…”
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Potential anticancer properties and mechanisms of thymoquinone in colorectal cancer
Published in Cancer cell international (12-12-2023)“…Colorectal neoplasms are one of the deadliest diseases among all cancers worldwide. Thymoquinone (TQ) is a natural compound of Nigella sativa that has been…”
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Interactions of melatonin with various signaling pathways: implications for cancer therapy
Published in Cancer cell international (29-12-2022)“…Melatonin is a neuro-hormone with conserved roles in evolution. Initially synthetized as an antioxidant molecule, it has gained prominence as a key molecule in…”
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15
MicroRNAs and colorectal cancer chemoresistance: New solution for old problem
Published in Life sciences (1973) (15-10-2020)“…Colorectal cancer (CRC) is one of the most common gastrointestinal malignancies with a significant mortality rate. Despite the great advances in cancer…”
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DNA damage response and repair in colorectal cancer: Defects, regulation and therapeutic implications
Published in DNA repair (01-09-2018)“…DNA damage response, a key factor involved in maintaining genome integrity and stability, consists of several kinase-dependent signaling pathways, which sense…”
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Polyphenols Modulate the miRNAs Expression that Involved in Glioblastoma
Published in Mini reviews in medicinal chemistry (01-01-2024)“…Glioblastoma multiforme (GBM), a solid tumor that develops from astrocytes, is one of the most aggressive types of brain cancer. While there have been…”
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FOXO1, a tiny protein with intricate interactions: Promising therapeutic candidate in lung cancer
Published in Biomedicine & pharmacotherapy (31-12-2023)“…Nowadays, lung cancer is the most common cause of cancer-related deaths in both men and women globally. Despite the development of extremely efficient targeted…”
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Nanotechnology-based advances in the efficient delivery of melatonin
Published in Cancer cell international (29-01-2022)“…N-[2-(5-methoxy-1H-indol-3-yl) ethyl] or simply melatonin is a biogenic amine produced by pineal gland and recently recognized various other organs. Because of…”
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Peroxisome Proliferator-Activated Receptors and their Ligands in Cancer Drug- Resistance: Opportunity or Challenge
Published in Anti-cancer agents in medicinal chemistry (01-01-2016)“…Development of resistance in cancer cells results in a high failure rate in cancer chemotherapy in the clinic. Therefore, investigating the mechanisms by which…”
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