Search Results - "Majidian, Sina"
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1
NGS based haplotype assembly using matrix completion
Published in PloS one (26-03-2019)“…We apply matrix completion methods for haplotype assembly from NGS reads to develop the new HapSVT, HapNuc, and HapOPT algorithms. This is performed by…”
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2
Hap10: reconstructing accurate and long polyploid haplotypes using linked reads
Published in BMC bioinformatics (18-06-2020)“…Haplotype information is essential for many genetic and genomic analyses, including genotype-phenotype associations in human, animals and plants. Haplotype…”
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3
Minimum error correction-based haplotype assembly: Considerations for long read data
Published in PloS one (12-06-2020)“…The single nucleotide polymorphism (SNP) is the most widely studied type of genetic variation. A haplotype is defined as the sequence of alleles at SNP sites…”
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4
Transcriptomic data reveals the dynamics of terpenoids biosynthetic pathway of fenugreek
Published in BMC genomics (22-04-2024)“…Medicinal plants are rich sources for treating various diseases due their bioactive secondary metabolites. Fenugreek (Trigonella foenum-graecum) is one of the…”
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5
Genomic variant benchmark: if you cannot measure it, you cannot improve it
Published in Genome Biology (05-10-2023)“…Genomic benchmark datasets are essential to driving the field of genomics and bioinformatics. They provide a snapshot of the performances of sequencing…”
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6
When less is more: sketching with minimizers in genomics
Published in Genome Biology (14-10-2024)“…The exponential increase in sequencing data calls for conceptual and computational advances to extract useful biological insights. One such advance,…”
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7
The GIAB genomic stratifications resource for human reference genomes
Published in Nature communications (19-10-2024)“…Despite the growing variety of sequencing and variant-calling tools, no workflow performs equally well across the entire human genome. Understanding…”
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8
Matrix Completion Using Graph Total Variation Based on Directed Laplacian Matrix
Published in Circuits, systems, and signal processing (01-06-2021)“…We propose two graph matrix completion algorithms called GMCM-DL and GMCR-DL, by employing a new definition of Graph Total Variation for matrices based on the…”
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9
Bioinformatics Evaluation of SPATA19 Gene Expression in Different Parts of Brain
Published in Research in molecular medicine (01-05-2021)“…Background: Determining the expression pattern of testis genes in the brain is essential for understanding tissue functions and correlation or…”
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Inference of phylogenetic trees directly from raw sequencing reads using Read2Tree
Published in Nature biotechnology (01-01-2024)“…Current methods for inference of phylogenetic trees require running complex pipelines at substantial computational and labor costs, with additional constraints…”
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OMAMO: orthology-based alternative model organism selection
Published in Bioinformatics (13-05-2022)“…Abstract Summary The conservation of pathways and genes across species has allowed scientists to use non-human model organisms to gain a deeper understanding…”
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12
Phylogenetic placement of whole genome duplications in yeasts through quantitative analysis of hierarchical orthologous groups [version 1; peer review: 1 approved with reservations, 1 not approved]
Published in F1000 research (2023)“…Background: Whole genome duplications (WGD) are genomic events leading to formation of polyploid organisms. Resulting duplicated genes play important roles in…”
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13
OMAMO: orthology-based alternative model organism selection
Published in Bioinformatics (Oxford, England) (13-05-2022)“…The conservation of pathways and genes across species has allowed scientists to use non-human model organisms to gain a deeper understanding of human biology…”
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14
Responses of cucumber (Cucumis sativus L.) rhizosphere microbial community to some agronomic management practices
Published in FEMS microbiology ecology (01-08-2021)“…ABSTRACT The microbial communities associated to the rhizosphere (the rhizomicrobiome) have a substantial impact on plant growth and yield. Understanding the…”
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15
Hybrid experimental and numerical approach for assessment of non-linear dynamic behavior of soil-nailed retaining walls
Published in International journal of non-linear mechanics (01-07-2020)“…Seismic Performance-based design demands reliable means for profound understanding of inelastic and non-linear dynamic behavior of civil structures. In this…”
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16
Haplotype Assembly Using Manifold Optimization and Error Correction Mechanism
Published in IEEE signal processing letters (01-06-2019)“…Recent matrix completion based methods have not been able to properly model the haplotype assembly problem for noisy observations. To deal with such cases, we…”
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17
Effect of fine material content on the CBR of Iran saturated soils
Published in Innovative infrastructure solutions : the official journal of the Soil-Structure Interaction Group in Egypt (SSIGE) (01-12-2022)“…The California bearing ratio (CBR) is an important index of soil quality for use in road construction and base stabilization. The CBR test can be performed in…”
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OMA orthology in 2024: improved prokaryote coverage, ancestral and extant GO enrichment, a revamped synteny viewer and more in the OMA Ecosystem
Published in Nucleic acids research (05-01-2024)“…Abstract In this update paper, we present the latest developments in the OMA browser knowledgebase, which aims to provide high-quality orthology inferences and…”
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PhaseME: Automatic rapid assessment of phasing quality and phasing improvement
Published in Gigascience (01-07-2020)“…The detection of which mutations are occurring on the same DNA molecule is essential to predict their consequences. This can be achieved by phasing the genomic…”
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Anti-angiogenic effects of testis-specific gene antigen 10 on primary endothelial cells
Published in Gene (05-09-2020)“…•Reduced expression of angiogenesis-related genes in TSGA10 over-expressing HUVECs.•Inhibitory effects of over-expressing TSGA10 on VEGF-stimulated…”
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