Search Results - "Majid, Shahbazi"
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Transcriptome Profiling of Cisplatin Resistance in Triple-negative Breast Cancer: New Insight into the Role of PI3k/Akt Pathway
Published in Current molecular medicine (01-01-2023)“…Aggressive nature of triple negative breast cancer (TNBC) is associated with poor prognosis compared with other breast cancer types. Current guidelines…”
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Contribution of HLA class II genes, DRB401:01, DRB107:01, and DQB103:03:2 to clinical features of Vitiligo disease in Iranian population
Published in Molecular biology reports (2022)“…Background Vitiligo is a multifactorial depigmentation condition, which is due to skin melanocyte destruction. Increased expression of HLA class II genes in…”
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Hypoxia-inducible tumour-specific promoters as a dual-targeting transcriptional regulation system for cancer gene therapy
Published in Ecancermedicalscience (06-07-2017)“…Transcriptional targeting is the best approach for specific gene therapy. Hypoxia is a common feature of the tumour microenvironment. Therefore, targeting gene…”
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4
Lenalidomide improves NKG2D-based CAR-T cell activity against colorectal cancer cells invitro
Published in Heliyon (01-10-2023)“…Although CAR-based immunotherapy is viewed as a promising treatment for tumors, particularly hematological malignancies, solid tumors can pose challenges. It…”
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Interleukin‐1 gene cluster Haplotype analysis in the chronic outcome prediction of the Hepatitis B virus infection
Published in Journal of medical virology (01-03-2018)“…Hepatitis B virus (HBV) infection is well known as an important cause of the chronic liver disease. The screening of the genotype of certain cytokines might be…”
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Harnessing the TP53INP1/TP53I3 axis for inhibition of colorectal cancer cell proliferation through MEG3 and Linc-ROR Co-expression
Published in Heliyon (30-07-2024)“…Dysregulation of long noncoding RNAs (lncRNAs), such as maternally expressed gene 3 (MEG3) and long intergenic noncoding RNA regulator of reprogramming…”
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Enhancing protein production and growth in chinese hamster ovary cells through miR-107 overexpression
Published in AMB Express (01-02-2024)“…Chinese Hamster Ovary (CHO) cells are widely employed as host cells for biopharmaceutical production. The manufacturing of biopharmaceuticals poses several…”
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Study of the Effect of Sustainable Architecture on the Design of Residential Buildings (Case Study: Qazvin Pardis Complex)
Published in Civil and environmental engineering (Berlin) (01-12-2018)“…Housing is a widespread and complex issue with a variety of dimensions. First, housing was considered as a physical location and as a shelter and basic…”
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The correction of ETV6/RUNX1 translocation in acute lymphocytic leukemia cells: a new gene targeting system by homologous recombination mechanism
Published in Journal of applied genetics (01-02-2020)“…Regarding the uncertainty of the exact cause of the acute lymphocytic leukemia (ALL) caused by ETV6-RUNX1t(12;21) translocation, correcting genes of the ETV6…”
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Development and Characterization of Paclitaxel-Loaded MF59 Nano-emulsion for Breast Cancer Therapy
Published in BioNanoScience (2024)“…This study aimed to evaluate the potential of MF59 nano-emulsion as a carrier for the sustained release of paclitaxel (PTX) and its effects on the human breast…”
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Fibroblast Growth Factor-2 Levels are Elevated in The Serum of Patients with Multiple Sclerosis
Published in Iranian journal of immunology (01-06-2022)“…Background: Various factors contribute to the pathogenesis of Multiple Sclerosis (MS), one of which is Fibroblast Growth Factor 2 (FGF2). The function of FGF2…”
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Enhancing productivity of Chinese hamster ovary (CHO) cells: synergistic strategies combining low-temperature culture and mTORC1 signaling engineering
Published in Frontiers in bioengineering and biotechnology (2023)“…The growing demand for recombinant proteins in medicine has prompted biopharmaceutical companies to seek ways to maximize the manufacturing process. Despite…”
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The Human IL-23 Decoy Receptor Inhibits T-Cells Producing IL-17 by Genetically Engineered Mesenchymal Stem Cells
Published in International journal of cell biology (2018)“…The immunomodulatory and self-renewable features of human adipose mesenchymal stem cells (hAD-MSCs) mark their importance in regenerative medicine. Interleukin…”
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14
Association assessment of platelet derived growth factor B gene polymorphism and its expression status with susceptibility to coronary artery disease
Published in The Egyptian journal of medical human genetics (01-10-2017)“…Coronary artery disease (CAD) is the most frequent cause of morbidity and mortality in the world and it is known as a multifactorial disorder which is…”
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15
Identification of hub genes associated with RNAi-induced silencing of XIAP through targeted proteomics approach in MCF7 cells
Published in Cell & bioscience (11-06-2020)“…The X-linked inhibitor of apoptosis protein (XIAP) is the most potent caspase inhibitor of the IAP family in apoptosis pathway. This study aims to identify the…”
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Data Mining for Identification of Forkhead Box O (FOXO3a) in Different Organisms Using Nucleotide and Tandem Repeat Sequences
Published in Research in molecular medicine (30-03-2020)“…Background: Deregulation of FOXO3a gene which belongs to Forkhead box O (FOXO) transcription factors, can cause cancer (e.g. breast cancer). FOXO factors have…”
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3-Dimensional Model to Study Apoptosis Induction of Activated Natural Killer Cells Conditioned Medium Using Patient-Derived Colorectal Cancer Organoids
Published in Frontiers in cell and developmental biology (26-05-2022)“…Natural killer (NK) cells are innate lymphocytes that can kill tumor cells via different pathways, including the secretion of cytotoxic granules in…”
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New insights into the roles of the FOXO3 and P27Kip1 genes in signaling pathways
Published in Upsala journal of medical sciences (03-07-2019)“…Background: The forkhead box O3 (FOXO3) and p27Kip1 are two important genes in breast cancer progression. In the present study we analyzed the effect of…”
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Relationship between human leukocyte antigen (HLA)-DQA10102/HLA-DQB10602 polymorphism and preeclampsia
Published in International journal of reproductive biomedicine (Yazd, Iran) (01-09-2017)“…Preeclampsia is a condition associated with systemic disorders in the mother and the fetus. However, the exact causes of preeclampsia are unknown, but several…”
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Evaluation of IL-17 Serum Level, Brain Inflammation and Demyelination in Experimental Autoimmune Encephalomyelitis C57BL/6 Mice Model with Different Doses of Myelin Oligodendrocyte Glycoprotein
Published in Iranian journal of allergy, asthma, and immunology (08-06-2019)“…Multiple sclerosis (MS) is an autoimmune disease that affects the central nervous system.MS creates a wide range of symptoms with lifelong debilitating…”
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