Search Results - "Majchrzak, J."

Peripheral Administration of a Long-Acting Peptide Oxytocin Receptor Agonist Inhibits Fear-Induced Freezing by Modi, Meera E, Majchrzak, Mark J, Fonseca, Kari R, Doran, Angela, Osgood, Sarah, Vanase-Frawley, Michelle, Feyfant, Eric, McInnes, Heather, Darvari, Ramin, Buhl, Derek L, Kablaoui, Natasha M

“…Oxytocin (OT) modulates the expression of social and emotional behaviors and consequently has been proposed as a pharmacologic treatment of psychiatric…”
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Preclinical characterization of selective phosphodiesterase 10A inhibitors: a new therapeutic approach to the treatment of schizophrenia by Schmidt, C J, Chapin, D S, Cianfrogna, J, Corman, M L, Hajos, M, Harms, J F, Hoffman, W E, Lebel, L A, McCarthy, S A, Nelson, F R, Proulx-LaFrance, C, Majchrzak, M J, Ramirez, A D, Schmidt, K, Seymour, P A, Siuciak, J A, Tingley, 3rd, F D, Williams, R D, Verhoest, P R, Menniti, F S

“…We have recently proposed the hypothesis that inhibition of the cyclic nucleotide phosphodiesterase (PDE) 10A may represent a new pharmacological approach to…”
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Dramatic elevation in urinary amino terminal titin fragment excretion quantified by immunoassay in Duchenne muscular dystrophy patients and in dystrophin deficient rodents by Robertson, Alan S, Majchrzak, Mark J, Smith, Courtney M, Gagnon, Robert C, Devidze, Nino, Banks, Glen B, Little, Sean C, Nabbie, Fizal, Bounous, Denise I, DiPiero, Janet, Jacobsen, Leslie K, Bristow, Linda J, Ahlijanian, Michael K, Stimpson, Stephen A

“…Highlights • New immunoassays were developed for quantification of amino-terminal fragments of titin in urine. • A 365-fold increase in urinary titin…”
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Pharmacological disruption of mouse social approach behavior: Relevance to negative symptoms of schizophrenia by Hanks, Ashley N., Dlugolenski, Keith, Hughes, Zoë A., Seymour, Patricia A., Majchrzak, Mark J.

“…•Social approach behavior was not disrupted by NMDA antagonists.•The disruption induced by d-amphetamine was variable and was not reversed by…”
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Distance Estimation With a Long-Range Ultrasonic Sensor System by Majchrzak, J., Michalski, M., Wiczynski, G.

“…This paper presents the results of tests conducted with an ultrasonic proximity measurement system (composed of Polaroid 600 sensors and a Sonar Ranging Module…”
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Modulation of NMDA receptor function by inhibition of d-amino acid oxidase in rodent brain by Strick, Christine A., Li, Cheryl, Scott, Liam, Harvey, Brian, Hajós, Mihály, Steyn, Stefanus J., Piotrowski, Mary A., James, Larry C., Downs, James T., Rago, Brian, Becker, Stacey L., El-Kattan, Ayman, Xu, Youfen, Ganong, Alan H., Tingley, F. David, Ramirez, Andres D., Seymour, Patricia A., Guanowsky, Victor, Majchrzak, Mark J., Fox, Carol B., Schmidt, Christopher J., Duplantier, Allen J.

“…Observations that N-Methyl- d-Aspartate (NMDA) antagonists produce symptoms in humans that are similar to those seen in schizophrenia have led to the current…”
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Phosphodiesterase 9A regulates central cGMP and modulates responses to cholinergic and monoaminergic perturbation in vivo by Kleiman, Robin J, Chapin, Douglas S, Christoffersen, Curt, Freeman, Jody, Fonseca, Kari R, Geoghegan, Kieran F, Grimwood, Sarah, Guanowsky, Victor, Hajós, Mihály, Harms, John F, Helal, Christopher J, Hoffmann, William E, Kocan, Geralyn P, Majchrzak, Mark J, McGinnis, Dina, McLean, Stafford, Menniti, Frank S, Nelson, Fredrick, Roof, Robin, Schmidt, Anne W, Seymour, Patricia A, Stephenson, Diane T, Tingley, Francis David, Vanase-Frawley, Michelle, Verhoest, Patrick R, Schmidt, Christopher J

“…Cyclic nucleotides are critical regulators of synaptic plasticity and participate in requisite signaling cascades implicated across multiple neurotransmitter…”
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The Weight of Pharmacokinetic Parameters for Mycophenolic Acid in Prediction of Rejection Outcome: The Receiver Operating Characteristic Curve Analysis by Pawinski, T., Durlik, M., Szlaska, I., Urbanowicz, A., Ostrowska, J., Gralak, B., Majchrzak, J.

“…Often the clinical researcher is confronted with the question of how accurate a particular laboratory test is to identify disease. To confirm the ability of…”
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Tobacco Industry CSR activities in Poland between 2020-2023 by Dera, P, Banach, M, Majchrzak, J, Balwicki, Ł

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Preclinical pharmacology of the α4β2 nAChR partial agonist varenicline related to effects on reward, mood and cognition by Rollema, Hans, Hajós, Mihály, Seymour, Patricia A., Kozak, Rouba, Majchrzak, Mark J., Guanowsky, Victor, Horner, Weldon E., Chapin, Doug S., Hoffmann, William E., Johnson, David E., Mclean, Stafford, Freeman, Jody, Williams, Kathryn E.

“…Effects of the α4β2 nAChR partial agonist varenicline, an efficacious smoking cessation aid, in animal models of addiction, depression, cognition and…”
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Preclinical pharmacology of the alpha 4 beta 2 nAChR partial agonist varenicline related to effects on reward, mood and cognition by Rollema, Hans, Hajos, Mihaly, Seymour, Patricia A, Kozak, Rouba, Majchrzak, Mark J, Guanowsky, Victor, Horner, Weldon E, Chapin, Doug S, Hoffmann, William E, Johnson, David E, Mclean, Stafford, Freeman, Jody, Williams, Kathryn E

“…The pharmacological properties and pharmacokinetic profile of the alpha 4 beta 2 nicotinic acetylcholine receptor (nAChR) partial agonist varenicline provide…”
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Effects of systemic and intracerebroventricular administration of mecamylamine, a nicotinic cholinergic antagonist, on spatial memory in rats by DECKER, M. W, MAJCHRZAK, M. J

“…The effects of both systemic and intracerebroventricular administration of mecamylamine, a nicotinic antagonist, were tested on the Morris water maze…”
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Tubular and Glomerular Proteinuria in Diagnosing Chronic Allograft Nephropathy With Relevance to the Degree of Urinary Albumin Excretion by Cieciura, T., Urbanowicz, A., Perkowska-Ptasinska, A., Nowacka-Cieciura, E., Tronina, O., Majchrzak, J., Baczkowska, T., Matlosz, B., Danielewicz, R., Nazarewski, S., Durlik, M.

“…The diagnosis of chronic allograft nephropathy (CAN) is based on pathological examination according to Banff 97 schema. The aim of the study was to evaluate…”
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Dopamine D3/D2 Receptor Antagonist PF-4363467 Attenuates Opioid Drug-Seeking Behavior without Concomitant D2 Side Effects by Wager, Travis T, Chappie, Thomas, Horton, David, Chandrasekaran, Ramalakshmi Y, Samas, Brian, Dunn-Sims, Elizabeth R, Hsu, Cathleen, Nawreen, Nawshaba, Vanase-Frawley, Michelle A, O’Connor, Rebecca E, Schmidt, Christopher J, Dlugolenski, Keith, Stratman, Nancy C, Majchrzak, Mark J, Kormos, Bethany L, Nguyen, David P, Sawant-Basak, Aarti, Mead, Andy N

“…Dopamine receptor antagonism is a compelling molecular target for the treatment of a range of psychiatric disorders, including substance use disorders. From…”
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Effects of lobeline, a nicotinic receptor agonist, on learning and memory by Decker, M W, Majchrzak, M J, Arnerić, S P

“…The effects of (-)-lobeline were assessed in two learning and memory tasks in which nicotine-induced enhancement of performance has previously been…”
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Centrally administered opioid peptides stimulate saccharin intake in nondeprived rats by Gosnell, B A, Majchrzak, M J

“…Endogenous opioid peptides are thought to play a role in mediating the pleasurable or rewarding aspects of the ingestion of certain foods and liquids. We…”
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Effects of nicotine on spatial memory deficits in rats with septal lesions by Decker, M W, Majchrzak, M J, Anderson, D J

“…Impaired septohippocampal function has been implicated in the memory deficits associated with Alzheimer's disease (AD), and septal lesions have been used to…”
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The effects of morphine on diet selection are dependent upon baseline diet preferences by Gosnell, B A, Krahn, D D, Majchrzak, M J

“…It has been reported that morphine causes a selective increase in the intake of dietary fat. Because we have noted considerable variability among rats in their…”
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Synthesis, sar and pharmacology of CP-293,019 : A potent, selective dopamine D4 receptor antagonist by SANNER, M. A, CHAPPIE, T. A, MAJCHRZAK, M. J, FARACI, W. S, COLLINS, J. L, DUIGNAN, D. B, DI PRETE, C. C, LEE, J. S, TROZZI, A, DUNAISKIS, A. R, FLIRI, A. F, DESAI, K. A, ZORN, S. H, JACKSON, E. R, JOHNSON, C. G, MORRONE, J. M, SEYMOUR, P. A

“…A series of novel, potent and selective pyrido[1,2-a]pyrazine dopamine D4 receptor antagonists are reported including CP-293,019 (D4 Ki = 3.4 nM, D2 Ki > 3,310…”
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Relationship between nicotine tolerance questionnaire scores and plasma cotinine by Pomerleau, C S, Pomerleau, O F, Majchrzak, M J, Kloska, D D, Malakuti, R

“…The Fagerström Tolerance Questionnaire (TQ) is often used in both research and treatment contexts to evaluate nicotine tolerance and physiological dependence…”
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