Search Results - "Maixner, Nitzan"

Transcriptional Dysregulation of Adipose Tissue Autophagy in Obesity by Maixner, Nitzan, Bechor, Sapir, Vershinin, Zlata, Pecht, Tal, Goldstein, Nir, Haim, Yulia, Rudich, Assaf

“…There is growing interest in understanding how dysregulated autophagy may contribute to pathogenesis of disease. Most frequently, disease states are associated…”
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The Obesity-Susceptibility Gene TMEM18 Promotes Adipogenesis through Activation of PPARG by Landgraf, Kathrin, Klöting, Nora, Gericke, Martin, Maixner, Nitzan, Guiu-Jurado, Esther, Scholz, Markus, Witte, A. Veronica, Beyer, Frauke, Schwartze, Julian T., Lacher, Martin, Villringer, Arno, Kovacs, Peter, Rudich, Assaf, Blüher, Matthias, Kiess, Wieland, Körner, Antje

“…TMEM18 is the strongest candidate for childhood obesity identified from GWASs, yet as for most GWAS-derived obesity-susceptibility genes, the functional…”
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Assessing Obesity-Related Adipose Tissue Disease (OrAD) to Improve Precision Medicine for Patients Living With Obesity by Pincu, Yair, Yoel, Uri, Haim, Yulia, Makarenkov, Nataly, Maixner, Nitzan, Shaco-Levy, Ruthy, Bashan, Nava, Dicker, Dror, Rudich, Assaf

“…Obesity is a heterogenous condition that affects the life and health of patients to different degrees and in different ways. Yet, most approaches to treat…”
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Adaptation of fuel selection to acute decrease in voluntary energy expenditure is governed by dietary macronutrient composition in mice by Bhandarkar, Nikhil S., Lahav, Rotem, Maixner, Nitzan, Haim, Yulia, Wong, G. William, Rudich, Assaf, Yoel, Uri

“…In humans, exercise‐induced thermogenesis is a markedly variable component of total energy expenditure, which had been acutely affected worldwide by COVID‐19…”
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Visceral Adipose Tissue E2F1-miRNA206/210 Pathway Associates with Type 2 Diabetes in Humans with Extreme Obesity by Maixner, Nitzan, Haim, Yulia, Blüher, Matthias, Chalifa-Caspi, Vered, Veksler-Lublinsky, Isana, Makarenkov, Nataly, Yoel, Uri, Bashan, Nava, Liberty, Idit F, Kukeev, Ivan, Dukhno, Oleg, Levy, Dan, Rudich, Assaf

“…Objective: Up-regulated expression of transcription-factor E2F1 in human visceral adipose tissue (VAT) characterizes a dysmetabolic obesity sub-phenotype. An…”
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Leptin stimulates autophagy/lysosome-related degradation of long-lived proteins in adipocytes by Goldstein, Nir, Haim, Yulia, Mattar, Pamela, Hadadi-Bechor, Sapir, Maixner, Nitzan, Kovacs, Peter, Blüher, Matthias, Rudich, Assaf

“…Obesity, a condition most commonly associated with hyper-leptinemia, is also characterized by increased expression of autophagy genes and likely autophagic…”
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A marked decrease in preterm deliveries during the coronavirus disease 2019 pandemic by Meyer, Raanan, Bart, Yossi, Tsur, Abraham, Yinon, Yoav, Friedrich, Lior, Maixner, Nitzan, Levin, Gabriel

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Real-world evidence for immunotherapy in the first line setting in small cell lung cancer by Sagie, Shira, Maixner, Nitzan, Stemmer, Amos, Lobachov, Anastasiya, Bar, Jair, Urban, Damien

“…OBJECTIVEDespite major progress over the past decade in the field of lung cancer care, only mild advances have occurred in Small Cell Lung Cancer (SCLC), with…”
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Somatic USP8 alteration affects the immune landscape of corticotroph pituitary adenomas– a pilot study by Greidinger, Dahlia, Halperin, Reut, Zemet, Roni, Maixner, Nitzan, Tirosh, Amit

“…Introduction Somatic mutations in ubiquitin-specific protease-8 ( USP8 ), encoding a deubiquinating protein, are found in approximately 30% of…”
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Hematologic adaptation to mask‐wearing among pregnant women and obstetrical outcome during the coronavirus disease 2019 pandemic by Friedrich, Lior, Levin, Gabriel, Maixner, Nitzan, Bart, Yossi, Tsur, Abraham, Yinon, Yoav, Meyer, Raanan

“…Objective To evaluate the effect of the coronavirus disease 2019 (COVID‐19) mask‐wearing on hematological laboratory components and obstetrical outcomes among…”
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A Different View: Unenhanced Computed Tomography versus Magnetic Resonance Imaging Scans in Metastatic Spinal Cord Compression by Maixner, Nitzan, Weissbuch, Yulian, Amital, Howard, Kirshenboim, Zehavit

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Arthroplasty Rates and Risk in Familial Mediterranean Fever Patients: A large Population-Based Study by Ben-Shabat, Niv, Fisher, Lior, Maixner, Nitzan, Arow, Mohamad, Ozeri, David J, Patt, Yonatan Shneor, Watad, Abdulla, Amital, Howard, Gendelman, Omer

“…Familial Mediterranean Fever (FMF) is a genetic disorder characterized by recurrent episodes of fever and inflammation in various organs, including the joints…”
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A TRAIL-TL1A Paracrine Network Involving Adipocytes, Macrophages, and Lymphocytes Induces Adipose Tissue Dysfunction Downstream of E2F1 in Human Obesity by Maixner, Nitzan, Pecht, Tal, Haim, Yulia, Chalifa-Caspi, Vered, Goldstein, Nir, Tarnovscki, Tania, Liberty, Idit F, Kirshtein, Boris, Golan, Rachel, Berner, Omer, Monsonego, Alon, Bashan, Nava, Blüher, Matthias, Rudich, Assaf

“…Elevated expression of E2F1 in adipocyte fraction of human visceral adipose tissue (hVAT) associates with a poor cardiometabolic profile. We hypothesized that…”
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CTRP6 rapidly responds to acute nutritional changes, regulating adipose tissue expansion and inflammation in mice by Lahav, Rotem, Haim, Yulia, Bhandarkar, Nikhil S, Levin, Liron, Chalifa-Caspi, Vered, Sarver, Dylan, Sahagun, Ageline, Maixner, Nitzan, Kovesh, Barr, Wong, G William, Rudich, Assaf

“…In chronic obesity, activated adipose tissue proinflammatory cascades are tightly linked to metabolic dysfunction. Yet, close temporal analyses of the…”
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Human adipose tissue is a putative direct target of daytime orexin with favorable metabolic effects: A cross‐sectional study by Goldstein, Nir, Tsuneki, Hiroshi, Bhandarkar, Nikhil, Aimaretti, Eleonora, Haim, Yulia, Kon, Kanta, Sato, Kiyofumi, Wada, Tsutomu, Liberty, Idit F., Kirshtein, Boris, Dukhno, Oleg, Maixner, Nitzan, Gepner, Yftach, Sasaoka, Toshiyasu, Rudich, Assaf

“…Objective Orexin/hypocretin (Ox) and its receptors (OxR), a neuroendocrine system centrally regulating sleep/wakefulness, were implicated in the regulation of…”
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Autophagy in Adipose Tissue by Maixner, Nitzan, Kovsan, Julia, Harman-Boehm, Ilana, Blüher, Matthias, Bashan, Nava, Rudich, Assaf

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