Search Results - "Maitland, Kristen"
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Volumetric imaging of human mesenchymal stem cells (hMSCs) for non-destructive quantification of 3D cell culture growth
Published in PloS one (28-03-2023)“…The adoption of cell-based therapies into the clinic will require tremendous large-scale expansion to satisfy future demand, and bioreactor-microcarrier…”
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2
Confocal Endomicroscopy: Instrumentation and Medical Applications
Published in Annals of biomedical engineering (01-02-2012)“…Advances in fiber optic technology and miniaturized optics and mechanics have propelled confocal endomicroscopy into the clinical realm. This high resolution,…”
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3
In vivo microscopy as an adjunctive tool to guide detection, diagnosis, and treatment
Published in Journal of biomedical optics (01-04-2022)“…Significance: There have been numerous academic and commercial efforts to develop high-resolution in vivo microscopes for a variety of clinical use cases,…”
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4
Comparison of polystyrene and hydrogel microcarriers for optical imaging of adherent cells
Published in Journal of biomedical optics (01-06-2024)“…The ability to observe and monitor cell density and morphology has been imperative for assessing the health of a cell culture and for producing high quality,…”
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5
Intravital Fluorescence Excitation in Whole-Animal Optical Imaging
Published in PloS one (22-02-2016)“…Whole-animal fluorescence imaging with recombinant or fluorescently-tagged pathogens or cells enables real-time analysis of disease progression and treatment…”
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6
Optical axial scanning in confocal microscopy using an electrically tunable lens
Published in Biomedical optics express (01-02-2014)“…This paper presents the use and characterization of an electrically focus tunable lens to perform axial scanning in a confocal microscope. Lateral and axial…”
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7
Clinical label-free biochemical and metabolic fluorescence lifetime endoscopic imaging of precancerous and cancerous oral lesions
Published in Oral oncology (01-06-2020)“…•Autofluorescence lifetime imaging (FLIM) endoscopy of oral lesions was demonstrated.•FLIM endoscopy enables label-free biochemical and metabolic imaging of…”
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8
A pulse coupled neural network segmentation algorithm for reflectance confocal images of epithelial tissue
Published in PloS one (27-03-2015)“…Automatic segmentation of nuclei in reflectance confocal microscopy images is critical for visualization and rapid quantification of nuclear-to-cytoplasmic…”
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9
Optical model of the murine lung to optimize pulmonary illumination
Published in Journal of biomedical optics (01-07-2018)“…We describe a Monte Carlo model of the mouse torso to optimize illumination of the mouse lung for fluorescence detection of low levels of pulmonary pathogens,…”
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10
Enhanced detection of oral dysplasia by structured illumination fluorescence lifetime imaging microscopy
Published in Scientific reports (02-03-2021)“…We demonstrate that structured illumination microscopy has the potential to enhance fluorescence lifetime imaging microscopy (FLIM) as an early detection…”
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11
Volumetric structured illumination microscopy enabled by a tunable-focus lens
Published in Optics letters (01-11-2015)“…We present a mechanical-scan-free method for volumetric imaging of biological tissue. The optical sectioning is provided by structured illumination, and the…”
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12
Chromatic confocal microscopy for multi-depth imaging of epithelial tissue
Published in Biomedical optics express (01-05-2013)“…We present a novel chromatic confocal microscope capable of volumetric reflectance imaging of microstructure in non-transparent tissue. Our design takes…”
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13
A scalable system for generation of mesenchymal stem cells derived from induced pluripotent cells employing bioreactors and degradable microcarriers
Published in Stem cells translational medicine (01-12-2021)“…Human mesenchymal stem cells (hMSCs) are effective in treating disorders resulting from an inflammatory or heightened immune response. The hMSCs derived from…”
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14
Porous Shape-Memory Polymers
Published in Polymer reviews (01-01-2013)“…Porous shape memory polymers (SMPs) include foams, scaffolds, meshes, and other polymeric substrates that possess porous three-dimensional macrostructures…”
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15
Fluorescence modeling of in vivo optical detection of Mycobacterium tuberculosis
Published in Biomedical optics express (01-10-2019)“…Tuberculosis is one of the deadliest infectious diseases worldwide. New tools to study pathogenesis and monitor subjects in pre-clinical studies to develop…”
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16
Handheld tunable focus confocal microscope utilizing a double-clad fiber coupler for in vivo imaging of oral epithelium
Published in Journal of biomedical optics (01-05-2017)“…A reflectance confocal endomicroscope with double-clad fiber coupler and electrically tunable focus lens is applied to imaging of the oral mucosa. The…”
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17
Quantifiable Intravital Light Sheet Microscopy
Published in Methods in molecular biology (Clifton, N.J.) (2022)“…Live imaging of zebrafish embryos that maintains normal development can be difficult to achieve due to a combination of sample mounting, immobilization, and…”
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18
An ultraviolet‐curable, core–shell vaccine formed via phase separation
Published in Journal of biomedical materials research. Part A (01-10-2019)“…One of the central challenges in the field of vaccine delivery is to develop a delivery method that maintains antigen stability while also enabling control…”
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19
A novel multimodal optical imaging system for early detection of oral cancer
Published in Oral surgery, oral medicine, oral pathology and oral radiology (01-03-2016)“…Objectives Several imaging techniques have been advocated as clinical adjuncts to improve identification of suspicious oral lesions. However, these have not…”
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Handheld multispectral fluorescence lifetime imaging system for in vivo applications
Published in Biomedical optics express (01-03-2014)“…There is an increasing interest in the application of fluorescence lifetime imaging (FLIM) for medical diagnosis. Central to the clinical translation of FLIM…”
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