Search Results - "Maitland, Derek J."

Blunted epidermal L‐tryptophan metabolism in vitiligo affects immune response and ROS scavenging by Fenton chemistry, part 2: epidermal H2O2/ONOO–‐mediated stress in vitiligo hampers indoleamine 2,3‐dioxygenase and aryl hydrocarbon receptor‐mediated immune response signaling by Schallreuter, Karin U., Salem, Mohamed A. E. L., Gibbons, Nick C. J., Maitland, Derek J., Marsch, Elke, Elwary, Souna M. A., Healey, Andrew R.

“…Vitiligo is characterized by a mostly progressive loss of the inherited skin color. The cause of the disease is still unknown, despite accumulating in vivo and…”
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Methionine Sulfoxide Reductases A and B Are Deactivated by Hydrogen Peroxide (H2O2) in the Epidermis of Patients with Vitiligo by Schallreuter, Karin U., Rübsam, Katharina, Gibbons, Nicholas C.J., Maitland, Derek J., Chavan, Bhaven, Zothner, Carsten, Rokos, Hartmut, Wood, John M.

“…Patients with the depigmentation disorder vitiligo have low catalase expression/activities and constantly accumulate 10−3M hydrogen peroxide (H2O2) in their…”
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Specific interaction of the diastereomers 7(R)- and 7(S)-tetrahydrobiopterin with phenylalanine hydroxylase: implications for understanding primapterinuria and vitiligo by Pey, Angel L, Martinez, Aurora, Charubala, Ramamurthy, Maitland, Derek J, Teigen, Knut, Calvo, Ana, Pfleiderer, Wolfgang, Wood, John M, Schallreuter, Karin U

“…Pterin-4a-carbinolamine dehydratase (PCD) is an essential component of the phenylalanine hydroxylase (PAH) system, catalyzing the regeneration of the essential…”
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Presence of epidermal allantoin further supports oxidative stress in vitiligo by Shalbaf, Mohammad, Gibbons, Nicholas C. J., Wood, John M., Maitland, Derek J., Rokos, Hartmut, Elwary, Souna M, Marles, Lee K., Schallreuter, Karin U.

“…:  Xanthine dehydrogenase/xanthine oxidase (XDH/XO) catalyses the hydroxylation of hypoxanthine to xanthine and finally to uric acid in purine degradation…”
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New anthraquinone dimer from the root bark of Cassia artemisioides (Gaudich. Ex. DC) Randell by Zaman, Khair, Khan, Mohammad Rafiullah, Ali, Mumtaz, Maitland, Derek J.

“…The phytochemical investigation of the root bark of Cassia artemisioides (Gaudich. Ex. DC) Randell resulted in the isolation of one new anthraquinone…”
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Pharmacological and biological evaluation of a series of substituted 1,4-naphthoquinone bioreductive drugs by Phillips, Roger M., Jaffar, Mohammed, Maitland, Derek J., Loadman, Paul M., Shnyder, Steven D., Steans, Gillian, Cooper, Patricia A., Race, Amanda, Patterson, Adam V., Stratford, Ian J.

“…The indolequinone compound EO9 has good pharmacodynamic properties in terms of bioreductive activation and selectivity for either NAD(P)H:quinone…”
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Evidence of Structure-Selective Fragmentations in the Tandem Mass Spectra of Protonated Hydroxyalkylamino-1,4-Naphthoquinones Formed by Electrospray Ionisation by Bowen, Richard D., Mahmood, Tariq, Maitland, Derek J., Mercer, Katharine E., Gallagher, Richard T.

“…The collision-induced dissociation of protonated hydroxyalkylamino-1,4-naphthoquinones depends strongly on the structure of the substituent [NHCH2(CH2)nOH, n =…”
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Blunted epidermal L‐tryptophan metabolism in vitiligo affects immune response and ROS scavenging by Fenton chemistry, part 2: epidermal H 2 O 2 /ONOO – ‐mediated stress in vitiligo hampers indoleamine 2,3‐dioxygenase and aryl hydrocarbon receptor‐mediated immune response signaling by Schallreuter, Karin U., Salem, Mohamed A. E. L., Gibbons, Nick C. J., Maitland, Derek J., Marsch, Elke, Elwary, Souna M. A., Healey, Andrew R.

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New alkaloids from Casimiroa edulis fruits and their pharmacological activity by Awaad, Amani S., Maitland, Derek J., Moneir, Samar M.

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13C NMR spectra of nylon 6/12 copolymers and related model compounds by Goodman, Isaac, Maitland, Derek J., Kehayoglou, Aristides H.

“…The 13C NMR spectra of model mono- to tetra-amides containing CO, (CH 2) 5 and (CH 2) 11 groups in varied sequential arrangements have been used to reinterpret…”
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