Search Results - "Maiti, Mohitosh"

Pre-microRNA binding aminoglycosides and antitumor drugs as inhibitors of Dicer catalyzed microRNA processing by Maiti, Mohitosh, Nauwelaerts, Koen, Herdewijn, Piet

“…Over-expressions of miRNAs are being increasingly linked with many diseases including different types of cancer. In this study, the role of some known small…”
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Xylonucleic acid: synthesis, structure, and orthogonal pairing properties by Maiti, Mohitosh, Maiti, Munmun, Knies, Christine, Dumbre, Shrinivas, Lescrinier, Eveline, Rosemeyer, Helmut, Ceulemans, Arnout, Herdewijn, Piet

“…There is a common interest for studying xeno-nucleic acid systems in the fields of synthetic biology and the origin of life, in particular, those with an…”
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Structural and Functional Elucidation of Peptide Ts11 Shows Evidence of a Novel Subfamily of Scorpion Venom Toxins by Cremonez, Caroline M, Maiti, Mohitosh, Peigneur, Steve, Cassoli, Juliana Silva, Dutra, Alexandre A A, Waelkens, Etienne, Lescrinier, Eveline, Herdewijn, Piet, de Lima, Maria Elena, Pimenta, Adriano M C, Arantes, Eliane C, Tytgat, Jan

“…To date, several families of peptide toxins specifically interacting with ion channels in scorpion venom have been described. One of these families comprise…”
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Where cone snails and spiders meet: design of small cyclic sodium‐channel inhibitors by Peigneur, Steve, Cheneval, Olivier, Maiti, Mohitosh, Leipold, Enrico, Heinemann, Stefan H., Lescrinier, Eveline, Herdewijn, Piet, De Lima, Maria Elena, Craik, David J., Schroeder, Christina I., Tytgat, Jan

“…ABSTRACT A 13 aa residue voltage‐gated sodium (Nav) channel inhibitor peptide, Pn, containing 2 disulfide bridges was designed by using a chimeric approach…”
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Molecular Dynamics of Double Stranded Xylo-Nucleic Acid by Ramaswamy, Amutha, Smyrnova, Daryna, Froeyen, Mathy, Maiti, Mohitosh, Herdewijn, Piet, Ceulemans, Arnout

“…Xylo-nucleic acid (XyloNA) is a synthetic analogue of ribo-nucleic acid (RNA), where the ribose sugar has been replaced by xylose. We present a molecular…”
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Aspartic acid based nucleoside phosphoramidate prodrugs as potent inhibitors of hepatitis C virus replication by Maiti, Munmun, Maiti, Mohitosh, Rozenski, Jef, De Jonghe, Steven, Herdewijn, Piet

“…In view of a persistent threat to mankind, the development of nucleotide-based prodrugs against hepatitis C virus (HCV) is considered as a constant effort in…”
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Stable Hairpin Structures Formed by Xylose‐Based Nucleic Acids by Mattelaer, Charles‐Alexandre, Maiti, Mohitosh, Smets, Laurent, Maiti, Munmun, Schepers, Guy, Mattelaer, Henri‐Philippe, Rosemeyer, Helmut, Herdewijn, Piet, Lescrinier, Eveline

“…Xenobiology explores synthetic nucleic acid polymers as alternative carriers of genetic information to expand the central dogma. The xylo‐ and…”
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Influence of the Nucleobase and Anchimeric Assistance of the Carboxyl Acid Groups in the Hydrolysis of Amino Acid Nucleoside Phosphoramidates by Maiti, Munmun, Michielssens, Servaas, Dyubankova, Natalia, Maiti, Mohitosh, Lescrinier, Eveline, Ceulemans, Arnout, Herdewijn, Piet

“…Nucleoside phosphoramidates (NPs) are a class of nucleotide analogues that has been developed as potential antiviral/antitumor prodrugs. Recently, we have…”
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Structure-Function Elucidation of a New α-Conotoxin, Lo1a, from Conus longurionis by Lebbe, Eline K.M., Peigneur, Steve, Maiti, Mohitosh, Devi, Prabha, Ravichandran, Samuthirapandian, Lescrinier, Eveline, Ulens, Chris, Waelkens, Etienne, D'Souza, Lisette, Herdewijn, Piet, Tytgat, Jan

“…α-Conotoxins are peptide toxins found in the venom of marine cone snails and potent antagonists of various subtypes of nicotinic acetylcholine receptors…”
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Synthesis of new biocarrier–nucleotide systems for cellular delivery in bacterial auxotrophic strains by De, Swarup, Groaz, Elisabetta, Maiti, Mohitosh, Pezo, Valérie, Marlière, Philippe, Herdewijn, Piet

“…In search for a delivery approach for thymidine monophosphate (TMP) in bacterial cells, we have synthesized a series of conjugates of TMP with biotin having an…”
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Solution Structure and Conformational Dynamics of Deoxyxylonucleic Acids (dXNA): An Orthogonal Nucleic Acid Candidate by Maiti, Mohitosh, Siegmund, Vanessa, Abramov, Mikhail, Lescrinier, Eveline, Rosemeyer, Helmut, Froeyen, Mathy, Ramaswamy, Amutha, Ceulemans, Arnout, Marx, Andreas, Herdewijn, Piet

“…Orthogonal nucleic acids are chemically modified nucleic acid polymers that are unable to transfer information with natural nucleic acids and thus can be used…”
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Discovery of a new subclass of α-conotoxins in the venom of Conus australis by Lebbe, Eline K.M., Peigneur, Steve, Maiti, Mohitosh, Mille, Bea G., Devi, Prabha, Ravichandran, Samuthirapandian, Lescrinier, Eveline, Waelkens, Etienne, D'Souza, Lisette, Herdewijn, Piet, Tytgat, Jan

“…Cone snails (Conus sp.) are poisonous animals that can be found in all oceans where they developed a venomous strategy to prey or to defend. The venom of these…”
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Structural and Binding Study of Modified siRNAs with the Argonaute 2 PAZ Domain by NMR Spectroscopy by Maiti, Mohitosh, Nauwelaerts, Koen, Lescrinier, Eveline, Herdewijn, Piet

“…By using high‐resolution NMR spectroscopy, the structures of a natural short interfering RNA (siRNA) and of several altritol nucleic acid (ANA)‐modified siRNAs…”
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Reactivity of Amino Acid Nucleoside Phosphoramidates: A Mechanistic Quantum Chemical Study by Michielssens, Servaas, Maiti, Munmun, Maiti, Mohitosh, Dyubankova, Natalia, Herdewijn, Piet, Ceulemans, Arnout

“…Recent experimental evidence (Maiti et al. Chem.Eur. J., submitted) indicates that hydrolysis of nucleoside phosphoramidates is subjected to anchimeric…”
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Structural and Binding Study of Modified siRNAs with the Argonaute2 PAZ Domain by NMR Spectroscopy by Maiti, Mohitosh, Nauwelaerts, Koen, Lescrinier, Eveline, Herdewijn, Piet

“…By using high-resolution NMR spectroscopy, the structures of a natural short interfering RNA (siRNA) and of several altritol nucleic acid (ANA)-modified siRNAs…”
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Self-complementary sequence context in mature miRNAs by Maiti, Mohitosh, Nauwelaerts, Koen, Lescrinier, Eveline, Schuit, Frans C., Herdewijn, Piet

“…MicroRNAs (miRNAs) are a class of 19–25 nt long non-coding RNAs that regulate gene expression post-transcriptionally by binding with partially complementary…”
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Enzymatic synthesis of DNA employing pyrophosphate-linked dinucleotide substrates by Song, Xiao-Ping, Maiti, Mohitosh, Herdewijn, Piet

“…Background One of the remaining questions in the understanding of the origin of Nature's information system is the way the first nucleic acids have been…”
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The chemical nature of the 2'-substituent in the pentose-sugar dictates the pseudoaromatic character of the nucleobase (pKa) in DNA/RNA by Chatterjee, Subhrangsu, Pathmasiri, Wimal, Plashkevych, Oleksandr, Honcharenko, Dmytro, Varghese, Oommen P, Maiti, Mohitosh, Chattopadhyaya, Jyoti

“…We here show that the pKa (error limit: 0.01 to 0.03 pKa unit) of a nucleobase in a nucleotide can be modulated by the chemical nature of the 2'-substituent at…”
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