Search Results - "Maiti, Debabrata"
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Decarboxylation as the Key Step in C−C Bond‐Forming Reactions
Published in Chemistry : a European journal (01-06-2017)“…C−C bond forming reactions incarnate the core of organic synthesis because of their fundamental applications to molecular diversity and complexity. In recent…”
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Arene diversification through distal C(sp 2 )-H functionalization
Published in Science (American Association for the Advancement of Science) (14-05-2021)“…Transition metal-catalyzed aryl C-H activation is a powerful synthetic tool as it offers step and atom-economical routes to site-selective functionalization…”
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3
Emergence of Pyrimidine-Based meta-Directing Group: Journey from Weak to Strong Coordination in Diversifying meta-C–H Functionalization
Published in Accounts of chemical research (01-02-2022)“…Conspectus C–H activation has emerged as a powerful transformative synthetic tool to construct complex molecular frameworks, which are ubiquitous in natural…”
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4
Hexafluoroisopropanol: the magical solvent for Pd-catalyzed C-H activation
Published in Chemical science (Cambridge) (10-02-2021)“…Among numerous solvents available for chemical transformations, 1,1,1,3,3,3-hexafluoro-2-propanol (popularly known as HFIP) has attracted enough attention of…”
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5
Carbon-Based Nanomaterials for Biomedical Applications: A Recent Study
Published in Frontiers in pharmacology (11-03-2019)“…The study of carbon-based nanomaterials (CBNs) for biomedical applications has attracted great attention due to their unique chemical and physical properties…”
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Toolbox for Distal C–H Bond Functionalizations in Organic Molecules
Published in Chemical reviews (23-03-2022)“…Transition-metal-catalyzed C–H activation has developed a contemporary approach to the omnipresent area of retrosynthetic disconnection. Scientific researchers…”
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7
Traditional and sustainable approaches for the construction of C–C bonds by harnessing C–H arylation
Published in Nature communications (28-02-2022)“…Biaryl scaffolds are found in natural products and drug molecules and exhibit a wide range of biological activities. In past decade, the transition…”
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8
Transition Metal Catalyzed Enantioselective C(sp2)–H Bond Functionalization
Published in ACS catalysis (04-12-2020)“…Direct catalytic transformation of C–H bonds to new functionalities has provided a powerful strategy to synthesize complex molecular scaffolds in a…”
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Template‐Assisted meta‐C−H Alkylation and Alkenylation of Arenes
Published in Angewandte Chemie International Edition (13-03-2017)“…To expand the scope of meta‐functionalization, a pyrimidine‐based template effective for the formation of β‐aryl aldehydes and ketones, using allyl alcohols,…”
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10
Deciphering the Role of Silver in Palladium-Catalyzed C–H Functionalizations
Published in ACS catalysis (06-08-2021)“…Over the years, silver salts have become an integral part of palladium-catalyzed C–H functionalization. Although most of the research works highlight the role…”
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Recent Advances in External-Directing-Group-Free C–H Functionalization of Carboxylic Acids without Decarboxylation
Published in ACS catalysis (02-04-2021)“…The selective functionalization of C–H bonds is an extremely important topic in present-day organic synthesis, as it utilizes the most abundant portion of a…”
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12
C-H deuteration of organic compounds and potential drug candidates
Published in Chemical Society reviews (19-04-2022)“…C-H deuteration has been intricately developed to satisfy the urgent need for site-selectively deuterated organic frameworks. Deuteration has been primarily…”
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13
Combining transition metals and transient directing groups for C-H functionalizations
Published in RSC advances (01-01-2018)“…In the domain of synthetic chemistry, C-H bond activation has always remained in the spotlight for researchers over the last few decades. Although different…”
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14
Diverse meta‐C−H Functionalization of Arenes across Different Linker Lengths
Published in Angewandte Chemie International Edition (25-06-2018)“…Arenes containing conformationally flexible long alkyl chains have been successfully functionalized at the meta‐position. Good to excellent meta selectivity is…”
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15
Meta-Selective Arene C–H Bond Olefination of Arylacetic Acid Using a Nitrile-Based Directing Group
Published in Organic letters (07-11-2014)“…A nitrile-based template attached with a phenylacetic acid framework promoted meta-selective C–H bond olefination. This palladium-catalyzed protocol is…”
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16
Palladium-Catalyzed Synthesis of Benzofurans and Coumarins from Phenols and Olefins
Published in Angewandte Chemie International Edition (25-11-2013)“…Triple CH functionalization: Palladium‐catalyzed synthesis of benzofurans and coumarins by reacting phenols and unactivated olefins is described. The reaction…”
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Palladium(II)-Catalyzed meta-CH Olefination: Constructing Multisubstituted Arenes through Homo-Diolefination and Sequential Hetero-Diolefination
Published in Angewandte Chemie International Edition (13-07-2015)“…Divinylbenzene derivatives represent an important class of molecular building blocks in organic chemistry and materials science. Reported herein is the…”
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Transition Metals and Transition Metals/Lewis Acid Cooperative Catalysis for Directing Group Assisted para-C–H Functionalization
Published in Chemistry letters (05-11-2020)“…In the past few decades, synthetic organic chemistry has been invigorated with the development of transition metal catalyzed directing group assisted…”
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Imine as a linchpin approach for meta-C–H functionalization
Published in Nature communications (02-03-2021)“…Despite the widespread applications of C–H functionalization, controlling site selectivity remains a significant challenge. Covalently attached directing…”
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Alkyne Linchpin Strategy for Drug:Pharmacophore Conjugation: Experimental and Computational Realization of a Meta-Selective Inverse Sonogashira Coupling
Published in Journal of the American Chemical Society (26-02-2020)“…The late-stage functionalization (LSF) of pharmaceutical and agrochemical compounds by the site-selective activation of C–H bonds provides access to diverse…”
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