Search Results - "Maisonneuve, I M"

18-MC reduces methamphetamine and nicotine self-administration in rats by Glick, S D, Maisonneuve, I M, Dickinson, H A

“…In previous studies, 18-methoxycoronaridine (18-MC), a novel iboga alkaloid congener, has been found to decrease the intravenous self-administration of…”
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U50,488, a kappa opioid receptor agonist, attenuates cocaine-induced increases in extracellular dopamine in the nucleus accumbens of rats by Maisonneuve, I M, Archer, S, Glick, S D

“…Because an increase in extracellular levels of dopamine in the nucleus accumbens has been associated with the reinforcing effects of addictive drugs, we…”
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Synthesis and Biological Evaluation of 18-Methoxycoronaridine Congeners. Potential Antiaddiction Agents by Kuehne, Martin E, He, Liwen, Jokiel, Patrick A, Pace, C. J, Fleck, M. W, Maisonneuve, I. M, Glick, Stanley D, Bidlack, Jean M

“…Variation of the methoxycarbonyl and C-18 substituents of the antiaddictive compound 18-methoxycoronaridine, and contraction of its isoquinuclidine ring…”
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Anti-addictive actions of an iboga alkaloid congener: a novel mechanism for a novel treatment by Maisonneuve, Isabelle M., Glick, Stanley D.

“…18-Methoxycoronaridine (18-MC), a novel iboga alkaloid congener that decreases drug self-administration in several animal models, may be a potential treatment…”
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Kappa opioid inhibition of morphine and cocaine self-administration in rats by Glick, Stanley D., Maisonneuve, Isabelle M., Raucci, John, Sydney, Archer

“…Two kappa agonists, U50,488 and spiradoline, produced dose-related acute decreases in both morphine and cocaine self-administration in rats; higher doses of…”
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Chronic administration of a cocaine "binge" alters basal extracellular levels in male rats: an in vivo microdialysis study by Maisonneuve, I M, Ho, A, Kreek, M J

“…The purpose of this study was to determine the effects of chronic "binge" administration of cocaine (hourly x 3 i.p.). Male Fisher rats were treated for 13…”
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Acute tolerance to the dopamine response induced by a binge pattern of cocaine administration in male rats: an in vivo microdialysis study by Maisonneuve, I M, Kreek, M J

“…To address a growing concern about the relevance of the pattern of cocaine administration used in animal studies, the aim of the present work was to establish…”
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18-Methoxycoronaridine, a non-toxic iboga alkaloid congener: effects on morphine and cocaine self-administration and on mesolimbic dopamine release in rats by Glick, S.D., Kuehne, M.E., Maisonneuve, I.M., Bandarage, U.K., Molinari, H.H.

“…Ibogaine, a naturally occurring iboga alkaloid, has been claimed to be effective in treating addiction to opioids and stimulants, and has been reported to…”
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18-Methoxycoronaridine (18-MC) and Ibogaine: Comparison of Antiaddictive Efficacy, Toxicity, and Mechanisms of Action by GLICK, STANLEY D., MAISONNEUVE, ISABELLE M., SZUMLINSKI, KAREN K.

“…18‐MC, a novel iboga alkaloid congener, is being developed as a potential treatment for multiple forms of drug abuse. Like ibogaine (40 mg/kg), 18‐MC (40…”
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Effects and aftereffects of ibogaine on morphine self-administration in rats by Glick, S D, Rossman, K, Steindorf, S, Maisonneuve, I M, Carlson, J N

“…Ibogaine, a naturally occurring alkaloid, has been claimed to be effective in treating addition to opiate and stimulant drugs. As a preclinical test of this…”
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An oral self-administration model of nicotine preference in rats : effects of mecamylamine by GLICK, S. D, VISKER, K. E, MAISONNEUVE, I. M

“…A new oral model of nicotine self-administration in rats has been described. The model utilizes a two-lever operant procedure with rats having a choice between…”
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Acute iboga alkaloid effects on extracellular serotonin (5-HT) levels in nucleus accumbens and striatum in rats by Wei, D., Maisonneuve, I.M., Kuehne, M.E., Glick, S.D.

“…The iboga alkaloid, ibogaine, its metabolite, noribogaine, and the congener, 18-methoxycoronaridine (18-MC) have all been claimed to have anti-addictive…”
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Interactions between iboga agents and methamphetamine sensitization: studies of locomotion and stereotypy in rats by Szumlinski, K K, Balogun, M Y, Maisonneuve, I M, Glick, S D

“…The phenomenon of sensitization has been theoretically implicated in mediating various aspects of drug addiction. Recent dose-response studies demonstrated…”
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(±)Cyclazocine blocks the dopamine response to nicotine by Maisonneuve, I M, Glick, S D

“…(±)CYCLAZOCINE, synthesized by Archer in 1962, was originally tested as a treatment for heroin addiction. (±)Cyclazocine is a mu opioid antagonist and kappa…”
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18-Methoxycoronardine attenuates nicotine-induced dopamine release and nicotine preferences in rats by GLICK, S. D, MAISONNEUVE, I. M, VISKER, K. E, FRITZ, K. A, BANDARAGE, U. K, KUEHNE, M. E

“…Two studies were conducted to assess, in vivo, potential anti-nicotinic effects of the iboga alkaloid ibogaine and its synthetic congener…”
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Enantioselective behavioral effects of sibutramine metabolites by Glick, Stanley D., Haskew, Renee E., Maisonneuve, Isabelle M., Carlson, Jeffrey N., Jerussi, Thomas P.

“…The anti-obesity agent, racemic ( RS)-sibutramine, has two active metabolites, desmethylsibutramine and didesmethylsibutramine. To the extent that sibutramine…”
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Ibogaine-like effects of noribogaine in rats by Glick, S.D., Pearl, S.M., Cai, J., Maisonneuve, I.M.

“…Ibogaine is a naturally occurring alkaloid that has been claimed to be effective in treating addiction to opioids and stimulants; a single dose is claimed to…”
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Effects of ibogaine on acute signs of morphine withdrawal in rats: independence from tremor by Glick, S D, Rossman, K, Rao, N C, Maisonneuve, I M, Carlson, J N

“…Because of the claim that ibogaine suppresses the symptoms of "narcotic withdrawal" in humans, the effect of ibogaine on naltrexone-precipitated withdrawal…”
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Attenuation of the reinforcing efficacy of morphine by 18-methoxycoronaridine by Maisonneuve, Isabelle M, Glick, Stanley D

“…In previous studies, 18-methoxycoronaridine, a novel iboga alkaloid congener, has been reported to decrease the self-administration of morphine, cocaine,…”
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Ibogaine and the dopaminergic response to nicotine by MAISONNEUVE, I. M, MANN, G. L, DEIBEL, C. R, GLICK, S. D

“…There is increasing evidence that the rewarding effect of nicotine is mediated by the mesolimbic dopamine system. The first objective of this study was to…”
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