Search Results - "Maison, David P"
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SARS-CoV-2 and the host-immune response
Published in Frontiers in immunology (19-06-2023)“…The SARS-CoV-2 pandemic and the COVID-19 disease have affected everyone globally, leading to one of recorded history's most significant research surges. As our…”
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Tuberculosis pathophysiology and anti-VEGF intervention
Published in Journal of clinical tuberculosis and other mycobacterial diseases (01-05-2022)“…[Display omitted] •A review of tuberculosis pathophysiology reveals only a few pharmaceutical targets.•Current drugs focus on targeting the bacteria and its…”
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Genomic analysis of SARS-CoV-2 variants of concern circulating in Hawai'i to facilitate public-health policies
Published in PloS one (01-12-2022)“…Using genomics, bioinformatics and statistics, herein we demonstrate the effect of statewide and nationwide quarantine on the introduction of SARS-CoV-2…”
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Dynamic SARS-CoV-2 emergence algorithm for rationally-designed logical next-generation vaccines
Published in Communications biology (10-10-2022)“…SARS-CoV-2 worldwide spread and evolution has resulted in variants containing mutations resulting in immune evasive epitopes that decrease vaccine efficacy. We…”
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The promise and reality of new immune profiling technologies
Published in Nature immunology (01-10-2024)“…This Comment discusses the explosion in innovative systems biology approaches in infectious disease studies. We outline the numerous challenges associated with…”
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Unmasking the hidden impact of viruses on tuberculosis risk
Published in Trends in immunology (01-09-2024)“…Viral co-infections in Mycobacterium tuberculosis (Mtb)-exposed individuals are potentially a risk factor for tuberculosis (TB) pathogenesis.Some chronic viral…”
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Altered mitochondrial respiration in peripheral blood mononuclear cells of post-acute sequelae of SARS-CoV-2 infection
Published in Mitochondrion (01-03-2024)“…•Peripheral blood mononuclear cells (PBMC) mitochondrial respiration weres measured ex vivo from participants without a history of COVID, with a history of…”
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The breadth of the neutralizing antibody response to original SARS‐CoV‐2 infection is linked to the presence of Long COVID symptoms
Published in Journal of medical virology (01-11-2023)“…The associations between longitudinal dynamics and the breadth of SARS‐CoV‐2 neutralizing antibody (nAb) response with various Long COVID phenotypes before…”
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Transcriptomic Profiling of Human Myocardium at Sudden Death to Define Vulnerable Substrate for Lethal Arrhythmias
Published in JACC. Clinical electrophysiology (01-11-2024)“…While some chronic pathological substrates for sudden cardiac death (SCD) are well known (eg, coronary artery disease and left ventricular [LV] dysfunction),…”
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10
Genomic analysis of SARS-CoV-2 variants of concern circulating in Hawai'i to facilitate public-health policies
Published in PloS one (01-12-2022)“…Using genomics, bioinformatics and statistics, herein we demonstrate the effect of statewide and nationwide quarantine on the introduction of SARS-CoV-2…”
Get full text
Journal Article -
11
Genetic Characteristics and Phylogeny of 969-bp S Gene Sequence of SARS-CoV-2 from Hawai‘i Reveals the Worldwide Emerging P681H Mutation
Published in Hawai'i journal of health & social welfare (01-03-2021)“…The COVID-19 pandemic has ravaged the world, caused over 1.8 million deaths in its first year, and severely affected the global economy. Hawai‘i has not been…”
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Journal Article -
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Virologic and Bioinformatic Analysis of SARS-CoV-2 to Facilitate Evidence-Based Public-Policy and Next-Generation Vaccine Design
Published 01-01-2023“…Severe acute respiratory coronavirus 2 (SARS-CoV-2), the causative agent of Coronavirus Disease 2019 (COVID-19), has been the scourge of the world for the past…”
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Dissertation -
13
Genetic Characteristics and Phylogeny of 969-bp S Gene Sequence of SARS-CoV-2 from Hawai'i Reveals the Worldwide Emerging P681H Mutation
Published in Hawai'i journal of health & social welfare (01-03-2021)“…The COVID-19 pandemic has ravaged the world, caused over 1.8 million deaths in its first year, and severely affected the global economy. Hawai'i has not been…”
Get full text
Journal Article