Search Results - "Mair, Theresia"
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ATAC-Seq Identifies Chromatin Landscapes Linked to the Regulation of Oxidative Stress in the Human Fungal Pathogen Candida albicans
Published in Journal of fungi (Basel) (01-09-2020)“…Human fungal pathogens often encounter fungicidal stress upon host invasion, but they can swiftly adapt by transcriptional reprogramming that enables pathogen…”
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A systematic review on the culture methods and applications of 3D tumoroids for cancer research and personalized medicine
Published in Cellular oncology (Dordrecht) (28-05-2024)“…Cancer is a highly heterogeneous disease, and thus treatment responses vary greatly between patients. To improve therapy efficacy and outcome for cancer…”
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The histone chaperone HIR maintains chromatin states to control nitrogen assimilation and fungal virulence
Published in Cell reports (Cambridge) (20-07-2021)“…Adaptation to changing environments and immune evasion is pivotal for fitness of pathogens. Yet, the underlying mechanisms remain largely unknown. Adaptation…”
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Mimicking Tumor Cell Heterogeneity of Colorectal Cancer in a Patient-derived Organoid-Fibroblast Model
Published in Cellular and molecular gastroenterology and hepatology (01-01-2023)“…Patient-derived organoid cancer models are generated from epithelial tumor cells and reflect tumor characteristics. However, they lack the complexity of the…”
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Abstract A011: Epigenetic vulnerabilities in patient-derived colorectal cancer organoids
Published in Cancer research (Chicago, Ill.) (01-12-2022)“…Abstract Colorectal cancer (CRC) is a major cause of cancer-related deaths worldwide. Here, we established human patient-derived colorectal cancer organoid…”
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Mimicking Tumor Cell Heterogeneity of Colorectal Cancer in a Patient-derived Organoid-Fibroblast ModelSummary
Published in Cellular and molecular gastroenterology and hepatology (01-01-2023)“…Background & Aims: Patient-derived organoid cancer models are generated from epithelial tumor cells and reflect tumor characteristics. However, they lack the…”
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