Search Results - "Maiocchi, Alessandro"
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Dissociation Kinetics of Open-Chain and Macrocyclic Gadolinium(III)-Aminopolycarboxylate Complexes Related to Magnetic Resonance Imaging: Catalytic Effect of Endogenous Ligands
Published in Chemistry : a European journal (14-12-2012)“…The kinetics of the metal exchange reactions between open‐chain Gd(DTPA)2− and Gd(DTPA‐BMA), macrocyclic Gd(DOTA)− and Gd(HP‐DO3A) complexes, and Cu2+ ions…”
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Photoacoustic imaging of integrin-overexpressing tumors using a novel ICG-based contrast agent in mice
Published in Photoacoustics (Munich) (01-09-2018)“…[Display omitted] PhotoAcoustic Imaging (PAI) is a biomedical imaging modality currently under evaluation in preclinical and clinical settings. In this work,…”
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Evaluation of docking procedures reliability in affitins-partners interactions
Published in Frontiers in chemistry (01-12-2022)“…Affitins constitute a class of small proteins belonging to Sul7d family, which, in microorganisms such as , bind DNA preventing its denaturation. Thanks to…”
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Design, Synthesis, Biological Evaluation, and NMR Studies of a New Series of Arylsulfones As Selective and Potent Matrix Metalloproteinase-12 Inhibitors
Published in Journal of medicinal chemistry (22-10-2009)“…Overexpression of macrophage elastase (MMP-12), a member of the matrix metalloproteinases family, can be linked to tissue remodeling and degradation in some…”
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Equilibrium Thermodynamics, Formation, and Dissociation Kinetics of Trivalent Iron and Gallium Complexes of Triazacyclononane-Triphosphinate (TRAP) Chelators: Unraveling the Foundations of Highly Selective Ga-68 Labeling
Published in Frontiers in chemistry (23-05-2018)“…In order to rationalize the influence of Fe contamination on labeling with the Ga eluted from Ge/ Ga- enerator, a detailed investigation was carried out on the…”
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The use of molecular descriptors in the design of gadolinium (III) chelates as MRI contrast agents
Published in Mini reviews in medicinal chemistry (01-12-2003)“…Nuclear Magnetic Resonance Imaging (MRI) is a very useful tool in modern medical diagnostics, especially when gadolinium(III)-based contrast agents are…”
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Conformational Characterization of Lanthanide(III)−DOTA Complexes by ab Initio Investigation in Vacuo and in Aqueous Solution
Published in Journal of the American Chemical Society (01-05-2002)“…The conformational behavior of four [Ln(DOTA)(H2O)]- systems (Ln = La, Gd, Ho, and Lu) has been characterized by means of ab initio calculations performed in…”
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Supramolecular adducts between macrocyclic Gd() complexes and polyaromatic systems: a route to enhance the relaxivity through the formation of hydrophobic interactions
Published in Chemical science (Cambridge) (04-02-2021)“…The set-up of reversible binding interactions between the hydrophobic region of macrocyclic GBCAs (Gadolinium Based Contrast Agents) and SO 3 − /OH containing…”
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Water-Soluble [Tc(N)(PNP)] Moiety for Room-Temperature 99m Tc Labeling of Sensitive Target Vectors
Published in Molecular pharmaceutics (07-03-2022)“…The incorporation of bioactive molecules into a water-soluble [ Tc][Tc(N)(PNP)]-based mixed compound is described. The method, which exploits the chemical…”
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P-178 - Water-soluble [Tc(N)(PNP)]-moiety for the room temperature labeling of sensitive molecules
Published in Nuclear medicine and biology (01-05-2022)Get full text
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Water-soluble [Tc(N)(PNP)]-moiety for the room temperature labeling of sensitive molecules
Published in Nuclear medicine and biology (01-05-2022)Get full text
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Water-Soluble [Tc(N)(PNP)] Moiety for Room-Temperature 99mTc Labeling of Sensitive Target Vectors
Published in Molecular pharmaceutics (07-03-2022)“…The incorporation of bioactive molecules into a water-soluble [99mTc][Tc(N)(PNP)]-based mixed compound is described. The method, which exploits the chemical…”
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13
Propeller performance on a model ship in straight and steady drift motions from single blade loads and flow field measurements
Published in Ocean engineering (01-02-2020)“…In the field of marine hydrodynamics, propeller operations in off-design conditions represent a challenging topic that has been increasingly attracting…”
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Boosting Bismuth(III) Complexation for Targeted α‐Therapy (TAT) Applications with the Mesocyclic Chelating Agent AAZTA
Published in Angewandte Chemie International Edition (24-10-2022)“…Targeted α therapy (TAT) is a promising tool in the therapy of cancer. The radionuclide 213BiIII shows favourable physical properties for this application, but…”
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Analysis of the hull wake of a twin-screw ship in steady drift by Borescope Stereo Particle Image Velocimetry
Published in Applied ocean research (01-11-2019)“…The hull wake of a twin-screw ship in steady drift is analysed by means of a novel Stereo Particle Image Velocimetry (SPIV) system based on rigid endoscopic…”
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Improved Efficacy of Synthesizing M III -Labeled DOTA Complexes in Binary Mixtures of Water and Organic Solvents. A Combined Radio- and Physicochemical Study
Published in Inorganic chemistry (21-05-2018)“…Typically, the synthesis of radiometal-based radiopharmaceuticals is performed in buffered aqueous solutions. We found that the presence of organic solvents…”
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In vivo tumor targeting and biodistribution evaluation of paramagnetic Solid Lipid Nanoparticles for Magnetic Resonance Imaging
Published in Nanomedicine (01-02-2017)“…Abstract The current study was performed to evaluate the in vivo efficiency of a new nano-sized contrast agent called paramagnetic Solid Lipid Nanoparticles,…”
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The Role of Equilibrium and Kinetic Properties in the Dissociation of Gd[DTPA-bis(methylamide)] (Omniscan) at near to Physiological Conditions
Published in Chemistry : a European journal (16-03-2015)“…[Gd(DTPA‐BMA)] is the principal constituent of Omniscan, a magnetic resonance imaging (MRI) contrast agent. In body fluids, endogenous ions (Zn2+, Cu2+, and…”
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Unexpected structural properties of Ln III complexes formed with the heptadentate AAZTA ligand
Published in Acta crystallographica. Section A, Foundations and advances (22-08-2018)“…Abstract only…”
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Environment‐specific spectral modeling: A new tool for the analysis of biological specimens
Published in Journal of biophotonics (01-03-2019)“…The recent discovery of fluorescent dyes for improving pathologic tissues identification has highlighted the need of robust methods for performance validation…”
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