Search Results - "Mainiero, Fabrizio"

Enriched environment reduces glioma growth through immune and non-immune mechanisms in mice by Garofalo, Stefano, D’Alessandro, Giuseppina, Chece, Giuseppina, Brau, Frederic, Maggi, Laura, Rosa, Alessandro, Porzia, Alessandra, Mainiero, Fabrizio, Esposito, Vincenzo, Lauro, Clotilde, Benigni, Giorgia, Bernardini, Giovanni, Santoni, Angela, Limatola, Cristina

“…Mice exposed to standard (SE) or enriched environment (EE) were transplanted with murine or human glioma cells and differences in tumour development were…”
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Environmental stimuli shape microglial plasticity in glioma by Garofalo, Stefano, Porzia, Alessandra, Mainiero, Fabrizio, Di Angelantonio, Silvia, Cortese, Barbara, Basilico, Bernadette, Pagani, Francesca, Cignitti, Giorgio, Chece, Giuseppina, Maggio, Roberta, Tremblay, Marie-Eve, Savage, Julie, Bisht, Kanchan, Esposito, Vincenzo, Bernardini, Giovanni, Seyfried, Thomas, Mieczkowski, Jakub, Stepniak, Karolina, Kaminska, Bozena, Santoni, Angela, Limatola, Cristina

“…In glioma, microglia and infiltrating macrophages are exposed to factors that force them to produce cytokines and chemokines, which contribute to tumor growth…”
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Functional cross talk between CXCR4 and PDGFR on glioblastoma cells is essential for migration by Sciaccaluga, Miriam, D'Alessandro, Giuseppina, Pagani, Francesca, Ferrara, Giuseppina, Lopez, Nadia, Warr, Tracy, Gorello, Paolo, Porzia, Alessandra, Mainiero, Fabrizio, Santoro, Antonio, Esposito, Vincenzo, Cantore, Giampaolo, Castigli, Emilia, Limatola, Cristina

“…Glioblastoma (GBM) is the most common and aggressive form of brain tumor, characterized by high migratory behavior and infiltration in brain parenchyma which…”
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Modulatory Effect of Gliadin Peptide 10-mer on Epithelial Intestinal CACO-2 Cell Inflammatory Response by Capozzi, Antonella, Vincentini, Olimpia, Gizzi, Pietro, Porzia, Alessandra, Longo, Agostina, Felli, Cristina, Mattei, Vincenzo, Mainiero, Fabrizio, Silano, Marco, Sorice, Maurizio, Misasi, Roberta

“…Celiac Disease (CD) is a chronic inflammatory enteropathy, triggered in genetically susceptible individuals by dietary gluten. Gluten is able to elicit…”
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The prostate specific membrane antigen regulates the expression of IL-6 and CCL5 in prostate tumour cells by activating the MAPK pathways by Colombatti, Marco, Grasso, Silvia, Porzia, Alessandra, Fracasso, Giulio, Scupoli, Maria Teresa, Cingarlini, Sara, Poffe, Ornella, Naim, Hassan Y, Heine, Martin, Tridente, Giuseppe, Mainiero, Fabrizio, Ramarli, Dunia

“…The interleukin-6 (IL-6) and the chemokine CCL5 are implicated in the development and progression of several forms of tumours including that of the prostate…”
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Safety of Multiple Vaccinations and Durability of Vaccine-Induced Antibodies in an Italian Military Cohort 5 Years after Immunization by Ferlito, Claudia, Visco, Vincenzo, Biselli, Roberto, Cattaruzza, Maria Sofia, Carreras, Giulia, Salerno, Gerardo, Lista, Florigio, Capobianchi, Maria Rosaria, Castilletti, Concetta, Lapa, Daniele, Antonelli, Guido, Gentile, Massimo, Sorice, Maurizio, Riitano, Gloria, Lucania, Giuseppe, Riccieri, Valeria, Mainiero, Fabrizio, Angeloni, Antonio, Lucarelli, Marco, Ferraguti, Giampiero, Autore, Alberto, Lastilla, Marco, Salemi, Simonetta, Biondo, Michela Ileen, Picchianti-Diamanti, Andrea, Caporuscio, Sara, Teloni, Raffaela, Mariotti, Sabrina, Nisini, Roberto, D'Amelio, Raffaele

“…We previously examined the safety and immunogenicity of multiple vaccines administered to a military cohort, divided into two groups, the first composed of…”
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The Adaptor Protein Shc Couples a Class of Integrins to the Control of Cell Cycle Progression by Wary, Kishore K, Mainiero, Fabrizio, Isakoff, Steven J, Marcantonio, Eugene E, Giancotti, Filippo G

“…We provide evidence that a class of integrins combines with the adaptor Shc and thereby with Grb2. Coimmunoprecipitation and mutagenesis experiments indicate…”
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HIV-1 Tat regulates endothelial cell cycle progression via activation of the Ras/ERK MAPK signaling pathway by Toschi, Elena, Bacigalupo, Ilaria, Strippoli, Raffaele, Chiozzini, Chiara, Cereseto, Anna, Falchi, Mario, Nappi, Filomena, Sgadari, Cecilia, Barillari, Giovanni, Mainiero, Fabrizio, Ensoli, Barbara

“…Tat, the transactivator of HIV-1 gene expression, is released by acutely HIV-1-infected T-cells and promotes adhesion, migration, and growth of inflammatory…”
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Inhibition of interleukin-8 (CXCL8/IL-8) responses by repertaxin, a new inhibitor of the chemokine receptors CXCR1 and CXCR2 by Casilli, Federica, Bianchini, Andrea, Gloaguen, Isabelle, Biordi, Leda, Alesse, Edoardo, Festuccia, Claudio, Cavalieri, Barbara, Strippoli, Raffaele, Cervellera, Maria Neve, Bitondo, Rosa Di, Ferretti, Elisabetta, Mainiero, Fabrizio, Bizzarri, Cinzia, Colotta, Francesco, Bertini, Riccardo

“…Repertaxin is a new non-competitive allosteric blocker of interleukin-8 (CXCL8/IL-8) receptors (CXCR1/R2), which by locking CXCR1/R2 in an inactive…”
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The coupling of α6β4 integrin to Ras-MAP kinase pathways mediated by Shc controls keratinocyte proliferation by Mainiero, Fabrizio, Murgia, Chiara, Wary, Kishore K., Curatola, Anna Maria, Pepe, Angela, Blumemberg, Miroslav, Westwick, John K., Der, Channing J., Giancotti, Filippo G.

“…The signaling pathways linking integrins to nuclear events are incompletely understood. We have examined intracellular signaling by the α6β4 integrin, a…”
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p38 MAPK is a critical regulator of the constitutive and the β4 integrin‐regulated expression of IL‐6 in human normal thymic epithelial cells by Mainiero, Fabrizio, Colombara, Michaela, Antonini, Valeria, Strippoli, Raffaele, Merola, Marcello, Poffe, Ornella, Tridente, Giuseppe, Ramarli, Dunia

“…Cytokines and adhesion receptors are key mediators in the dialog occurring between thymic epithelial cells (TEC) and thymocytes and regulating T cell…”
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Key role of proline‐rich tyrosine kinase 2 in interleukin‐8 (CXCL8/IL‐8)‐mediated human neutrophil chemotaxis by Di Cioccio, Vito, Strippoli, Raffaele, Bizzarri, Cinzia, Troiani, Giulia, Cervellera, Maria Neve, Gloaguen, Isabelle, Colagrande, Antonella, Cattozzo, Elisa Margherita, Pagliei, Sabrina, Santoni, Angela, Colotta, Francesco, Mainiero, Fabrizio, Bertini, Riccardo

“…Summary The signalling pathways leading to CXCL8/IL‐8‐induced human neutrophil migration have not been fully characterized. The present study demonstrates that…”
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IFN‐γ/IL‐6 and related cytokines in chronic spontaneous urticaria: evaluation of their pathogenetic role and changes during omalizumab therapy by Grieco, Teresa, Porzia, Alessandra, Paolino, Giovanni, Chello, Camilla, Sernicola, Alvise, Faina, Valentina, Carnicelli, Giorgia, Moliterni, Elisa, Mainiero, Fabrizio

“…Background Recent studies highlight that high levels of cytokines may precede the onset of many systemic autoimmune disorders and may also be related to…”
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Are ESPGHAN "biopsy-sparing" guidelines for celiac disease also suitable for asymptomatic patients? by Trovato, Chiara Maria, Montuori, Monica, Anania, Caterina, Barbato, Maria, Vestri, Anna Rita, Guida, Sofia, Oliva, Salvatore, Mainiero, Fabrizio, Cucchiara, Salvatore, Valitutti, Francesco

“…In 2012, European Society of Pediatric Gastroenterology, Hepatology, and Nutrition published novel guidelines on celiac disease (CD) diagnosis. Symptomatic…”
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Local allergic rhinitis in children: Novel diagnostic features and potential biomarkers by Zicari, Anna Maria, Occasi, Francesca, Di Fraia, Marco, Mainiero, Fabrizio, Porzia, Alessandra, Galandrini, Ricciarda, Giuffrida, Anna, Bosco, Daniela, Bertin, Serena, Duse, Marzia

“…Local allergic rhinitis (LAR) is a phenotype of rhinitis that has been poorly studied in children. It is characterized by the same symptoms of allergic…”
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The Glycoside Oleandrin Reduces Glioma Growth with Direct and Indirect Effects on Tumor Cells by Garofalo, Stefano, Grimaldi, Alfonso, Chece, Giuseppina, Porzia, Alessandra, Morrone, Stefania, Mainiero, Fabrizio, D'Alessandro, Giuseppina, Esposito, Vincenzo, Cortese, Barbara, Di Angelantonio, Silvia, Trettel, Flavia, Limatola, Cristina

“…Oleandrin is a glycoside that inhibits the ubiquitous enzyme Na /K -ATPase. In addition to its known effects on cardiac muscle, recent and evidence highlighted…”
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KCa3.1 channel inhibition sensitizes malignant gliomas to temozolomide treatment by D'Alessandro, Giuseppina, Grimaldi, Alfonso, Chece, Giuseppina, Porzia, Alessandra, Esposito, Vincenzo, Santoro, Antonio, Salvati, Maurizio, Mainiero, Fabrizio, Ragozzino, Davide, Di Angelantonio, Silvia, Wulff, Heike, Catalano, Myriam, Limatola, Cristina

“…Malignant gliomas are among the most frequent and aggressive cerebral tumors, characterized by high proliferative and invasive indexes. Standard therapy for…”
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Effect of surgery on pancreatic tumor-dependent lymphocyte asset: modulation of natural killer cell frequency and cytotoxic function by Iannone, Francesco, Porzia, Alessandra, Peruzzi, Giovanna, Birarelli, Patrizia, Milana, Bernardina, Sacco, Luca, Dinatale, Giuseppe, Peparini, Nadia, Prezioso, Giampaolo, Battella, Simone, Caronna, Roberto, Morrone, Stefania, Palmieri, Gabriella, Mainiero, Fabrizio, Chirletti, Piero

“…Tumor burden and invasiveness establish a microenvironment that surgery could alter. This study shows a comprehensive analysis of size, dynamics, and function…”
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Peripheral blood T cell alterations in newly diagnosed diffuse large B cell lymphoma patients and their long-term dynamics upon rituximab-based chemoimmunotherapy by Battella, Simone, Cox, M. Christina, La Scaleia, Raffaella, Di Napoli, Arianna, Di Landro, Francesca, Porzia, Alessandra, Franchitti, Lavinia, Mainiero, Fabrizio, Ruco, Luigi, Monarca, Bruno, Santoni, Angela, Palmieri, Gabriella

“…The importance of T cell-dependent immune responses in achieving long-term cure of chemoimmunotherapy-treated cancer patients is underscored by the recently…”
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Trasmembrane chemokines CX3CL1 and CXCL16 drive interplay between neurons, microglia and astrocytes to counteract pMCAO and excitotoxic neuronal death by Rosito, Maria, Lauro, Clotilde, Chece, Giuseppina, Porzia, Alessandra, Monaco, Lucia, Mainiero, Fabrizio, Catalano, Myriam, Limatola, Cristina, Trettel, Flavia

“…Upon noxious insults, cells of the brain parenchyma activate endogenous self-protective mechanisms to counteract brain damage. Interplay between microglia and…”
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