Search Results - "Maik, G."

Teixobactin kills bacteria by a two-pronged attack on the cell envelope by Shukla, Rhythm, Lavore, Francesca, Maity, Sourav, Derks, Maik G. N., Jones, Chelsea R., Vermeulen, Bram J. A., Melcrová, Adéla, Morris, Michael A., Becker, Lea Marie, Wang, Xiaoqi, Kumar, Raj, Medeiros-Silva, João, van Beekveld, Roy A. M., Bonvin, Alexandre M. J. J., Lorent, Joseph H., Lelli, Moreno, Nowick, James S., MacGillavry, Harold D., Peoples, Aaron J., Spoering, Amy L., Ling, Losee L., Hughes, Dallas E., Roos, Wouter H., Breukink, Eefjan, Lewis, Kim, Weingarth, Markus

“…Antibiotics that use novel mechanisms are needed to combat antimicrobial resistance 1 – 3 . Teixobactin 4 represents a new class of antibiotics with a unique…”
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An antibiotic from an uncultured bacterium binds to an immutable target by Shukla, Rhythm, Peoples, Aaron J., Ludwig, Kevin C., Maity, Sourav, Derks, Maik G.N., De Benedetti, Stefania, Krueger, Annika M., Vermeulen, Bram J.A., Harbig, Theresa, Lavore, Francesca, Kumar, Raj, Honorato, Rodrigo V., Grein, Fabian, Nieselt, Kay, Liu, Yangping, Bonvin, Alexandre M.J.J., Baldus, Marc, Kubitscheck, Ulrich, Breukink, Eefjan, Achorn, Catherine, Nitti, Anthony, Schwalen, Christopher J., Spoering, Amy L., Ling, Losee Lucy, Hughes, Dallas, Lelli, Moreno, Roos, Wouter H., Lewis, Kim, Schneider, Tanja, Weingarth, Markus

“…Antimicrobial resistance is a leading mortality factor worldwide. Here, we report the discovery of clovibactin, an antibiotic isolated from uncultured soil…”
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Specific Lipid Studies in Complex Membranes by Solid‐State NMR Spectroscopy by Beekveld, Roy A. M., Derks, Maik G. N., Kumar, Raj, Smid, Leanna, Maass, Thorben, Medeiros‐Silva, João, Breukink, Eefjan, Weingarth, Markus

“…Specific interactions with phospholipids are often critical for the function of proteins or drugs, but studying these interactions at high resolution remains…”
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Exploring a novel β-1,3-glucanosyltransglycosylase, MlGH17B, from a marine Muricauda lutaonensis strain for modification of laminari-oligosaccharides by Allahgholi, Leila, Derks, Maik G N, Dobruchowska, Justyna M, Jasilionis, Andrius, Moenaert, Antoine, Jouy, Léonie, Ara, Kazi Zubaida Gulshan, Linares-Pastén, Javier A, Friðjónsson, Ólafur H, Hreggviðsson, Guðmundur Óli, Karlsson, Eva Nordberg

“…Abstract The marine environment, contains plentiful renewable resources, e.g. macroalgae with unique polysaccharides, motivating search for enzymes from marine…”
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Chloromethyl Glycosides as Versatile Synthons to Prepare Glycosyloxymethyl‐Prodrugs by Elferink, Hidde, Titulaer, Willem H. C., Derks, Maik G. N., Veeneman, Gerrit H., Rutjes, Floris P. J. T., Boltje, Thomas J.

“…This work investigates the addition of monosaccharides to marketed drugs to improve their pharmacokinetic properties for oral absorption. To this end, a set of…”
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Host defence peptide plectasin targets bacterial cell wall precursor lipid II by a calcium-sensitive supramolecular mechanism by Jekhmane, Shehrazade, Derks, Maik G. N., Maity, Sourav, Slingerland, Cornelis J., Tehrani, Kamaleddin H. M. E., Medeiros-Silva, João, Charitou, Vicky, Ammerlaan, Danique, Fetz, Céline, Consoli, Naomi A., Cochrane, Rachel V. K., Matheson, Eilidh J., van der Weijde, Mick, Elenbaas, Barend O. W., Lavore, Francesca, Cox, Ruud, Lorent, Joseph H., Baldus, Marc, Künzler, Markus, Lelli, Moreno, Cochrane, Stephen A., Martin, Nathaniel I., Roos, Wouter H., Breukink, Eefjan, Weingarth, Markus

“…Antimicrobial resistance is a leading cause of mortality, calling for the development of new antibiotics. The fungal antibiotic plectasin is a eukaryotic host…”
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A survey on wireless sensor networks for smart grid by Fadel, Etimad, Gungor, V.C., Nassef, Laila, Akkari, Nadine, Malik, M.G. Abbas, Almasri, Suleiman, Akyildiz, Ian F.

“…The traditional power grid in many countries suffers from high maintenance costs and scalability issues along with the huge expense of building new power…”
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Genetic deletion of Cadm4 results in myelin abnormalities resembling Charcot-Marie-Tooth neuropathy by Golan, Neev, Kartvelishvily, Elena, Spiegel, Ivo, Salomon, Daniela, Sabanay, Helena, Rechav, Katya, Vainshtein, Anya, Frechter, Shahar, Maik-Rachline, Galia, Eshed-Eisenbach, Yael, Momoi, Takashi, Peles, Elior

“…The interaction between myelinating Schwann cells and the axons they ensheath is mediated by cell adhesion molecules of the Cadm/Necl/SynCAM family. This…”
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Exploring a novel β-1,3-glucanosyltransglycosylase, Ml GH17B, from a marine Muricauda lutaonensis strain for modification of laminari-oligosaccharides by Allahgholi, Leila, Derks, Maik G N, Dobruchowska, Justyna M, Jasilionis, Andrius, Moenaert, Antoine, Jouy, Léonie, Ara, Kazi Zubaida Gulshan, Linares-Pastén, Javier A, Friðjónsson, Ólafur H, Hreggviðsson, Guðmundur Óli, Karlsson, Eva Nordberg

“…The marine environment, contains plentiful renewable resources, e.g. macroalgae with unique polysaccharides, motivating search for enzymes from marine…”
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Application and Management of Cybersecurity Measures for Protection and Control by Holstein, Dennis, Cease, T. W., Seewald, Maik G.

“…This paper describes the work of CIGRE's JWG B5-D2.46 which is published in technical brochure #603. Described in this paper is a summary of the challenges…”
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Mechanisms and targets of glomerular damage by Rayego-Mateos, S., Rodrigues-Diez, R., Rodrigues-Diez, R. R., Lavoz-Barria, C., Alique, M., Mas, S., Pato, J., Keri, G., Egido, J., Ortiz, A., Ruiz-Ortega, M., Ying, L., Tepel, M., Frank, E., Florian, T., Gregor, T., Boye, J., Maik, G., Teng, B., Gu, C., Haller, H., Sever, S., Schiffer, M., Worthmann, K., Leitges, M., Dittrich-Breiholz, O., Kracht, M., Peired, A., Angelotti, M. L., Ronconi, E., Lazzeri, E., Sisti, A., Lasagni, L., Romagnani, P.

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Variable phosphorylation states of pigment-epithelium–derived factor differentially regulate its function by Maik-Rachline, Galia, Seger, Rony

“…The pigment epithelium–derived factor (PEDF) belongs to the family of noninhibitory serpins. Although originally identified in the eye, PEDF is widely…”
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Extracellular phosphorylation converts pigment epithelium–derived factor from a neurotrophic to an antiangiogenic factor by Maik-Rachline, Galia, Shaltiel, Shmuel, Seger, Rony

“…The pigment epithelium–derived factor (PEDF) belongs to the superfamily of serine protease inhibitors (serpin). There have been 2 distinct functions attributed…”
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Epigen, the Last Ligand of ErbB Receptors, Reveals Intricate Relationships between Affinity and Mitogenicity by Kochupurakkal, Bose S., Harari, Daniel, Di-Segni, Ayelet, Maik-Rachline, Galia, Lyass, Ljuba, Gur, Gal, Kerber, Gabriele, Citri, Ami, Lavi, Sara, Eilam, Raya, Chalifa-Caspi, Vered, Eshhar, Zelig, Pikarsky, Eli, Pinkas-Kramarski, Ronit, Bacus, Sarah S., Yarden, Yosef

“…Four ErbB receptors and multiple growth factors sharing an epidermal growth factor (EGF) motif underlie transmembrane signaling by the ErbB family in…”
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Truncated Vitronectins: Binding to Immobilized Fibrin and to Fibrin Clots, and Their Subsequent Interaction with Cells by Schvartz, Iris, Seger, Dalia, Maik-Rachline, Galia, Kreizman, Tamar, Shaltiel, Shmuel

“…The plasminogen activator inhibitor-1 (PAI-1) is stabilized in its inhibitory conformation by binding to Vitronectin (Vn). The anchorage of PAI-1 to the fibrin…”
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Bone mineral density in patients receiving suppressive doses of thyroxine for differentiated thyroid carcinoma by Görres, G, Kaim, A, Otte, A, Götze, M, Müller-Brand, J

“…To determine bone mineral density in patients with differentiated thyroid carcinoma receiving thyroxine replacement therapy in suppressive doses, we studied 65…”
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In Vivo Function of Tic22, a Protein Import Component of the Intermembrane Space of Chloroplasts by Rudolf, Mareike, Machettira, Anu B., Groß, Lucia E., Weber, Katrin L., Bolte, Kathrin, Bionda, Tihana, Sommer, Maik S., Maier, Uwe G., Weber, Andreas P.M., Schleiff, Enrico, Tripp, Joanna

“…Preprotein import into chloroplasts depends on macromolecular machineries in the outer and inner chloroplast envelope membrane （TOC and TIC）. It was suggested…”
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EFFECT OF ACUTE EXERCISE ON LYMPHOCYTE ENUMERATION IN HIV+ AFRICAN-AMERICAN FEMALES 904 by Maik-Rachline, G, LaPerriere, A, Perry, A, Klimas, N, Talluto, C, Goldstein, A, Majors, P, Junco, J, Ironson, G, Fletcher, M A, Schneiderman, N

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LOWER THAN PREDICTED HEART RATE RESPONSE TO MAX VO2 TESTING IN HIV-1 DISEASE1174 by Talluto, C, LaPerriere, A, Perry, A, Klimas, N, Maik-Rachline, G, Goldstein, A, Majors, P, Ironson, G, Fletcher, M A, Schneiderman, N

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