Search Results - "Maijer, Karen I"
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Stromal cell markers are differentially expressed in the synovial tissue of patients with early arthritis
Published in PloS one (09-08-2017)“…Previous studies have shown increased expression of stromal markers in synovial tissue (ST) of patients with established rheumatoid arthritis (RA). Here, ST…”
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Neo-Epitopes--Fragments of Cartilage and Connective Tissue Degradation in Early Rheumatoid Arthritis and Unclassified Arthritis
Published in PloS one (28-03-2016)“…Tissue destruction in rheumatoid arthritis (RA) is predominantly mediated by matrix metalloproteinases (MMPs), thereby generating protein fragments. Previous…”
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Impaired lymph node stromal cell function during the earliest phases of rheumatoid arthritis
Published in Arthritis research & therapy (26-02-2018)“…Systemic autoimmunity can be present years before clinical onset of rheumatoid arthritis (RA). Adaptive immunity is initiated in lymphoid tissue where lymph…”
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Serum Vaspin Levels Are Associated with the Development of Clinically Manifest Arthritis in Autoantibody-Positive Individuals
Published in PloS one (15-12-2015)“…We have previously shown that overweight may increase the risk of developing rheumatoid arthritis (RA) in autoantibody positive individuals. Adipose tissue…”
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Expression of Prostaglandin E2 Enzymes in the Synovium of Arthralgia Patients at Risk of Developing Rheumatoid Arthritis and in Early Arthritis Patients
Published in PloS one (30-07-2015)“…Arthralgia may precede the development of synovial inflammation in autoantibody-positive individuals at risk of developing rheumatoid arthritis (RA). A major…”
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Effects of B-cell directed therapy on the preclinical stage of rheumatoid arthritis: the PRAIRI study
Published in Annals of the rheumatic diseases (01-02-2019)“…We explored the effects of B-cell directed therapy in subjects at risk of developing autoantibodypositive rheumatoid arthritis (RA), who never experienced…”
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Lymph node biopsy analysis reveals an altered immunoregulatory balance already during the at‐risk phase of autoantibody positive rheumatoid arthritis
Published in European journal of immunology (01-12-2016)“…The balance between proinflammatory and regulatory CD4+ T cells is tightly controlled in lymphoid organs. In autoimmune diseases this balance is altered in the…”
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Dynamic Contrast‐Enhanced Magnetic Resonance Imaging Using Pharmacokinetic Modeling: Initial Experience in Patients With Early Arthritis
Published in Arthritis & rheumatology (Hoboken, N.J.) (01-03-2016)“…Objective Analysis of dynamic contrast‐enhanced magnetic resonance imaging (DCE‐MRI) using pharmacokinetic modeling (PKM) provides quantitative measures that…”
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Cutaneous non-allergic complications in tattoos: An overview of the literature
Published in La Presse médicale (1983) (01-12-2020)“…Tattooing is creating a permanent design by placing exogenous pigment particles and additives into the dermis. An adverse reaction may occur due to the act of…”
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Nuclear Factor-κB-inducing Kinase Is Expressed in Synovial Endothelial Cells in Patients with Early Arthritis and Correlates with Markers of Inflammation: A Prospective Cohort Study
Published in Journal of rheumatology (01-09-2015)“…The nuclear factor-κB (NF-κB) family of transcription factors is strongly involved in synovial inflammation. We have previously shown that NF-κB-inducing…”
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The effect of rituximab on patient reported outcomes in the preclinical phase of rheumatoid arthritis: 2 year data from the PRAIRI study
Published in Rheumatic & musculoskeletal diseases open (18-10-2024)“…ObjectivesEarly treatment of individuals at risk of developing rheumatoid arthritis (RA-risk) in the preclinical phase has the potential to positively impact…”
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Expression of Prostaglandin E.sub.2 Enzymes in the Synovium of Arthralgia Patients at Risk of Developing Rheumatoid Arthritis and in Early Arthritis Patients
Published in PloS one (30-07-2015)“…Objective Arthralgia may precede the development of synovial inflammation in autoantibody-positive individuals at risk of developing rheumatoid arthritis (RA)…”
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Serum Vaspin Levels Are Associated with the Development of Clinically Manifest Arthritis in Autoantibody-Positive Individuals: e0144932
Published in PloS one (01-12-2015)“…Objectives We have previously shown that overweight may increase the risk of developing rheumatoid arthritis (RA) in autoantibody positive individuals. Adipose…”
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