Search Results - "Maier, Sebastian K"

Copeptin in the Differential Diagnosis of Hyponatremia by Fenske, Wiebke, Störk, Stefan, Blechschmidt, Anne, Maier, Sebastian G. K., Morgenthaler, Nils G., Allolio, Bruno

“…Background: Treatment of patients with hyponatremia varies widely; thus, convenient diagnostic parameters are needed to guide the correct treatment strategy…”
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Utility and Limitations of the Traditional Diagnostic Approach to Hyponatremia: A Diagnostic Study by Fenske, Wiebke, Maier, Sebastian K.G, Blechschmidt, Anne, Allolio, Bruno, Störk, Stefan

“…Abstract Background The differential diagnosis of hyponatremia is often challenging because of its association with multiple underlying pathophysiological…”
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Transforming growth factor beta inhibition increases mortality and left ventricular dilatation after myocardial infarction by Frantz, Stefan, Hu, Kai, Adamek, Anna, Wolf, Jürgen, Sallam, Abed, KG Maier, Sebastian, Lonning, Scott, Ling, Hong, Ertl, Georg, Bauersachs, Johann

“…Background Transforming growth factor (TGF)-β is a locally generated cytokine involved in healing processes and tissue fibrosis, all relevant for cardiac…”
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Usefulness of Short-Term Variability of QT Intervals as a Predictor for Electrical Remodeling and Proarrhythmia in Patients With Nonischemic Heart Failure by Hinterseer, Martin, MD, Beckmann, Britt-Maria, MD, Thomsen, Morten B., PhD, Pfeufer, Arne, MD, BSc, Ulbrich, Michael, MD, Sinner, Moritz F., MD, Perz, Siegfried, MSc, Wichmann, H.-Erich, MD, PhD, Lengyel, Csaba, MD, PhD, Schimpf, Rainer, MD, PhD, Maier, Sebastian K.G., MD, PhD, Varró, András, MD, PhD, Vos, Marc A., PhD, Steinbeck, Gerhard, MD, PhD, Kääb, Stefan, MD, PhD

“…The high incidence of sudden cardiac death in heart failure (HF) reflects electrophysiologic changes in response to myocardial failure. We previously showed…”
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Single chamber implantable cardioverter defibrillator compared to dual chamber implantable cardioverter defibrillator: less is more! Data from the German Device Registry by Bogossian, Harilaos, Frommeyer, Gerrit, Hochadel, Matthias, Ince, Hüseyin, Spitzer, Stefan G., Eckardt, Lars, Maier, Sebastian K. G., Kleemann, Thomas, Brachmann, Johannes, Stellbrink, Christoph, Gonska, Bernd-Dieter, Kääb, Stefan, Senges, Jochen, Lemke, Bernd

“…Background In patients with high risk for sudden cardiac death the implantation of a defibrillator is an established treatment. However the benefits and risks…”
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Usefulness of an Implantable Loop Recorder to Detect Clinically Relevant Arrhythmias in Patients With Advanced Fabry Cardiomyopathy by Weidemann, Frank, MD, Maier, Sebastian K.G., MD, Störk, Stefan, MD, Brunner, Thomas, Liu, Dan, MD, Hu, Kai, MD, Seydelmann, Nora, MD, Schneider, Andreas, MD, Becher, Jan, MD, Canan-Kühl, Sima, MD, Blaschke, Daniela, MD, Bijnens, Bart, PhD, Ertl, Georg, MD, Wanner, Christoph, MD, Nordbeck, Peter, MD

“…Patients with genetic cardiomyopathy that involves myocardial hypertrophy often develop clinically relevant arrhythmias that increase the risk of sudden death…”
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Autonomic modulation and antiarrhythmic therapy in a model of long QT syndrome type 3 by Fabritz, Larissa, Damke, Dierk, Emmerich, Markus, Kaufmann, Susann G., Theis, Kathrin, Blana, Andreas, Fortmüller, Lisa, Laakmann, Sandra, Hermann, Sven, Aleynichenko, Elena, Steinfurt, Johannes, Volkery, Daniela, Riemann, Burkhard, Kirchhefer, Uwe, Franz, Michael R., Breithardt, Günter, Carmeliet, Edward, Schäfers, Michael, Maier, Sebastian K.G., Carmeliet, Peter, Kirchhof, Paulus

“…Aims Clinical observations in patients with long QT syndrome carrying sodium channel mutations (LQT3) suggest that bradycardia caused by parasympathetic…”
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Requirement of neuronal- and cardiac-type sodium channels for murine sinoatrial node pacemaking by Lei, Ming, Jones, Sandra A., Liu, Jie, Lancaster, Matthew K., Fung, Simon S.‐M., Dobrzynski, Halina, Camelliti, Patrizia, Maier, Sebastian K. G., Noble, Denis, Boyett, Mark R.

“…The majority of Na + channels in the heart are composed of the tetrodotoxin (TTX)-resistant ( K D , 2–6 μ m ) Na v 1.5 isoform; however, recently it has…”
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Evaluation of thoracic impedance trends for implant-based remote monitoring in heart failure patients - Results from the (J-)HomeCARE-II Study by Maier, Sebastian K.G., Paule, Stefan, Jung, Werner, Koller, Marcus, Ventura, Rodolfo, Quesada, Aurelio, Bordachar, Pierre, García-Fernández, F. Javier, Schumacher, Burghard, Lobitz, Nicole, Takizawa, Kaname, Ando, Kenji, Adachi, Kazumasa, Shoda, Morio

“…Remote monitoring by implantable devices substantially improves management of heart failure (HF) patients by providing diagnostic day-to-day data. The use of…”
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Patient delay and benefit of timely reperfusion in ST-segment elevation myocardial infarction by Scholz, Karl Heinrich, Meyer, Thomas, Lengenfelder, Björn, Vahlhaus, Christian, Tongers, Jörn, Schnupp, Steffen, Burckhard, Rainer, von Beckerath, Nicolas, Grusnick, Hans-Martin, Jeron, Andreas, Winter, Klaus Dieter, Maier, Sebastian K G, Danner, Michael, vom Dahl, Jürgen, Neef, Stefan, Stefanow, Stefan, Friede, Tim

“…BackgroundIn patients with ST-segment elevation myocardial infarction (STEMI), it is unknown how patient delay modulates the beneficial effects of timely…”
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An Unexpected Role for Brain-Type Sodium Channels in Coupling of Cell Surface Depolarization to Contraction in the Heart by Sebastian K. G. Maier, Westenbroek, Ruth E., Schenkman, Kenneth A., Feigl, Eric O., Scheuer, Todd, Catterall, William A.

“…Voltage-gated sodium channels composed of pore-forming α and auxiliary β subunits are responsible for the rising phase of the action potential in cardiac…”
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Conditional Neuronal Nitric Oxide Synthase Overexpression Impairs Myocardial Contractility by Burkard, Natalie, Rokita, Adam G, Kaufmann, Susann G, Hallhuber, Matthias, Wu, Rongxue, Hu, Kai, Hofmann, Ulrich, Bonz, Andreas, Frantz, Stefan, Cartwright, Elizabeth J, Neyses, Ludwig, Maier, Lars S, Maier, Sebastian K.G, Renné, Thomas, Schuh, Kai, Ritter, Oliver

“…The role of the neuronal NO synthase (nNOS or NOS1) enzyme in the control of cardiac function still remains unclear. Results from nNOS mice or from…”
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An Unexpected Requirement for Brain-Type Sodium Channels for Control of Heart Rate in the Mouse Sinoatrial Node by Sebastian K. G. Maier, Westenbroek, Ruth E., Yamanushi, T. T., Dobrzynski, H., Boyett, Mark R., Catterall, William A., Scheuer, Todd

“…Voltage-gated Na+ channels are composed of pore-forming α and auxiliary β subunits. The majority of Na+ channels in the heart contain tetrodotoxin…”
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Distribution and impact of age in patients with implantable cardioverter-defibrillators regarding early complications and 1-year clinical outcome: results from the German Device Registry by Kaya, Elif, Senges, Jochen, Hochadel, Matthias, Eckardt, Lars, Andresen, Dietrich, Ince, Hüseyin, Spitzer, Stefan G., Kleemann, Thomas, Maier, Sebastian S. K., Jung, Werner, Stellbrink, Christoph, Rassaf, Tienush, Wakili, Reza

“…Background Patients receiving implantable-cardioverter-defibrillators (ICD) in clinical practice are often older or younger than in clinical trials. Whether…”
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Ca2+/calmodulin-dependent protein kinase II regulates cardiac Na+ channels by Wagner, Stefan, Dybkova, Nataliya, Rasenack, Eva C L, Jacobshagen, Claudius, Fabritz, Larissa, Kirchhof, Paulus, Maier, Sebastian K G, Zhang, Tong, Hasenfuss, Gerd, Brown, Joan Heller, Bers, Donald M, Maier, Lars S

“…In heart failure (HF), Ca(2+)/calmodulin kinase II (CaMKII) expression is increased. Altered Na(+) channel gating is linked to and may promote ventricular…”
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Localization of sodium channel subtypes in mouse ventricular myocytes using quantitative immunocytochemistry by Westenbroek, Ruth E, Bischoff, Sebastian, Fu, Ying, Maier, Sebastian K.G, Catterall, William A, Scheuer, Todd

“…Abstract Voltage-gated sodium channels are responsible for the rising phase of the action potential in cardiac muscle. Previously, both TTX-sensitive neuronal…”
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Popeye domain containing proteins are essential for stress-mediated modulation of cardiac pacemaking in mice by Froese, Alexander, Breher, Stephanie S, Waldeyer, Christoph, Schindler, Roland F R, Nikolaev, Viacheslav O, Rinné, Susanne, Wischmeyer, Erhard, Schlueter, Jan, Becher, Jan, Simrick, Subreena, Vauti, Franz, Kuhtz, Juliane, Meister, Patrick, Kreissl, Sonja, Torlopp, Angela, Liebig, Sonja K, Laakmann, Sandra, Müller, Thomas D, Neumann, Joachim, Stieber, Juliane, Ludwig, Andreas, Maier, Sebastian K, Decher, Niels, Arnold, Hans-Henning, Kirchhof, Paulus, Fabritz, Larissa, Brand, Thomas

“…Cardiac pacemaker cells create rhythmic pulses that control heart rate; pacemaker dysfunction is a prevalent disorder in the elderly, but little is known about…”
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Detection of atrial high-rate events by continuous Home Monitoring: clinical significance in the heart failure-cardiac resynchronization therapy population by Shanmugam, Nesan, Boerdlein, Annegret, Proff, Jochen, Ong, Peter, Valencia, Oswaldo, Maier, Sebastian K.G., Bauer, Wolfgang R., Paul, Vince, Sack, Stefan

“…Aims Uncertainty exists over the importance of device-detected short-duration atrial arrhythmias. Continuous atrial diagnostics, through home monitoring (HM)…”
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Distribution and function of sodium channel subtypes in human atrial myocardium by Kaufmann, Susann G, Westenbroek, Ruth E, Maass, Alexander H, Lange, Volkmar, Renner, Andre, Wischmeyer, Erhard, Bonz, Andreas, Muck, Jenny, Ertl, Georg, Catterall, William A, Scheuer, Todd, Maier, Sebastian K.G

“…Abstract Voltage-gated sodium channels composed of a pore-forming α subunit and auxiliary β subunits are responsible for the upstroke of the action potential…”
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Long-term effects of a standardized feedback-driven quality improvement program for timely reperfusion therapy in regional STEMI care networks by Scholz, Karl Heinrich, Lengenfelder, Björn, Jacobshagen, Claudius, Fleischmann, Claus, Moehlis, Hiller, Olbrich, Hans G, Jung, Jens, Maier, Lars S, Maier, Sebastian Kg, Bestehorn, Kurt, Friede, Tim, Meyer, Thomas

“…Current European Society of Cardiology guidelines state that repetitive monitoring and feedback should be implemented for ST-elevation myocardial infarction…”
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