Search Results - "Mai, Wenyuan"
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Evaluating frequency of PML-RARA mutations and conferring resistance to arsenic trioxide-based therapy in relapsed acute promyelocytic leukemia patients
Published in Annals of hematology (01-11-2015)“…The aim of the study is to better understand the mechanism of relapse and acquired clinical resistance to arsenic trioxide (ATO) and/or all-trans retinoic acid…”
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2
Rituximab, lenalidomide and BTK inhibitor as frontline treatment for elderly or unfit patients with diffuse large B-cell lymphoma: a real-world analysis of single center
Published in Experimental hematology & oncology (16-09-2022)“…Abstract The combination of rituximab, lenalidomide, and Bruton’s tyrosine kinase inhibitor (BTKi) ibrutinib, followed by chemotherapy, has shown high efficacy…”
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3
The clinical impact of IKZF1 mutation in acute myeloid leukemia
Published in Experimental hematology & oncology (30-03-2023)“…Genetic heterogeneity poses a great challenge to the understanding and management of acute myeloid leukemia (AML). Knowledge of the IKZF1 mutation in AML…”
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4
Efficacy and prognostic factors of imatinib plus CALLG2008 protocol in adult patients with newly diagnosed Philadelphia chromosome-positive acute lymphoblastic leukemia
Published in Frontiers of medicine (01-06-2017)“…A CALLG2008 protocol was developed by the Chinese Acute Lymphoblastic Leukemia Cooperative Group for adult acute lymphoblastic leukemia (ALL). We…”
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5
Clinicopathological study on peripheral T-cell non-Hodgkin lymphoma with bone marrow involvement: a retrospective analysis from China
Published in International journal of hematology (01-10-2009)“…We reviewed 173 patients with an initial diagnosis of peripheral T - cell non-Hodgkin lymphoma (PTCL) and compared the patients with bone marrow involvement…”
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6
Efficacy and safety of venetoclax in combination with cytarabine and azacitidine (VAA) in relapsed/refractory acute myeloid leukemia: An open-label, single-arm, phase II study
Published in Journal of clinical oncology (01-06-2023)“…7025 Background: While the understanding of AML has been improved over decades, the outcome of relapsed/refractory AML remains dismal. Venetoclax-based regimen…”
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Venetoclax plus cytarabine and azacitidine in relapsed/refractory AML: An open-label, single-arm, phase 2 study
Published in European journal of cancer (1990) (01-05-2024)“…The outcome of relapsed/refractory (R/R) acute myeloid leukemia (AML) remains extremely poor. Venetoclax (VEN)-based regimens have shown promise in treating…”
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Venetoclax Combined with Hag Regimen in Newly Diagnosed ETP-ALL: Interim Analysis of a Prospective, Multicenter, Phase 2 Trial
Published in Blood (02-11-2023)“…Background: Early T-cell precursor (ETP) acute lymphoblastic leukemia (ALL) is identified as a subset of T-lineage ALL with a unique immunophenotype and genome…”
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9
Venetoclax Combined with Daunorubicin and Cytarabine (DAV) As Induction Therapy in De Novo Young Adult Acute Myeloid Leukemia
Published in Blood (23-11-2021)“…▪ Background: Anthracycline and cytarabine (“3+7”) have been the standard induction therapy for acute myeloid leukemia (AML) for almost 4 decades. Only 60%-70%…”
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10
A Real World Study of Venetoclax Combined with Azacitidine in 64 Chinese Patients Newly Diagnosed Acute Myeloid Leukemia
Published in Blood (23-11-2021)“…Background: Venetoclax combined with azacitidine has been demonstrated to have a favorable overall response rate and tolerable safety in acute myeloid leukemia…”
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11
Trimethoprim-sulfamethoxazole prevents interstitial pneumonitis in B-cell lymphoma patients receiving chemotherapy: a propensity score matching analysis
Published in Annals of hematology (01-09-2023)“…B-cell lymphoma is the most prevalent type of non-Hodgkin lymphoma, for which the standard treatment regimen includes rituximab combined with CHOP. However,…”
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12
Venetoclax plus 3 + 7 daunorubicin and cytarabine chemotherapy as first-line treatment for adults with acute myeloid leukaemia: a multicentre, single-arm, phase 2 trial
Published in The Lancet. Haematology (01-06-2022)“…Adults with acute myeloid leukaemia have unsatisfactory clinical outcomes and rates of complete remission. Venetoclax combined with azacytidine or low-dose…”
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13
How Induction Cycles before Remission Influence Long-Term Survival in Acute Myeloid Leukemia
Published in Blood (02-11-2023)“…Background : Acute myeloid leukemia (AML) is an aggressive hematologic malignancy characterized by accumulation and expansion of immature myeloid cells in the…”
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14
Effectivity of a modified Sanz risk model for early death prediction in patients with newly diagnosed acute promyelocytic leukemia
Published in Annals of hematology (01-11-2017)“…Early death is the main obstacle for the cure of patients with acute promyelocytic leukemia (APL). We have analyzed risk factors of early death from 526…”
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15
Dasatinib plus prednisone as induction and consolidation for adults with Ph-positive acute lymphoblastic leukaemia: A single-arm, multicentre, phase 2 trial
Published in British journal of haematology (01-09-2023)“…To reducing chemotherapy-related toxicity, the chemo-free regimens become a new trend of Ph + ALL treatment. Therefore, we conducted a phase 2 trial of…”
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16
New insights into the clinical characteristics of SETD2‐mutated acute myeloid leukaemia
Published in British journal of haematology (01-07-2023)“…Summary As reported, SETD2 is recurrently mutated in acute myeloid leukaemia (AML), but knowledge about the specifics is limited. We enrolled 530 consecutive…”
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17
Venetoclax plus daunorubicin and cytarabine in newly diagnosed acute myeloid leukemia patients: A propensity score‐matched analysis
Published in Hematological oncology (01-03-2024)“…Venetoclax plus 3 + 7 daunorubicin and cytarabine chemotherapy (DAV) has shown safety and efficacy in eligible patients with newly diagnosed acute myeloid…”
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18
High efficacy of arsenic trioxide plus all-trans retinoic acid based induction and maintenance therapy in newly diagnosed acute promyelocytic leukemia
Published in Leukemia research (01-01-2013)“…Abstract We conducted a retrospective study to evaluate the efficacy of combining arsenic trioxide (ATO) with all-trans-retinoic acid (ATRA) based induction…”
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19
Prognostic factors of patients with newly diagnosed acute promyelocytic leukemia treated with arsenic trioxide-based frontline therapy
Published in Leukemia research (01-09-2015)“…Highlights • We analyzed the prognostic factors of patients with newly diagnosed APL. • FLT3-ITD status and initial WBC count showed no effect on relapse-free…”
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20
Homoharringtonine in combination with cytarabine and aclarubicin in the treatment of refractory/relapsed acute myeloid leukemia: a single-center experience
Published in Annals of hematology (01-08-2013)“…To assess the efficacy and toxicity of HAA regimen (Homoharringtonine 4 mg/m 2 /day, days 1–3; cytarabine 150 mg/m 2 /day, days 1–7; aclarubicin 12 mg/m 2…”
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