Search Results - "Mai, Shi‐Juan"
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Epithelial cell adhesion molecule overexpression regulates epithelial-mesenchymal transition, stemness and metastasis of nasopharyngeal carcinoma cells via the PTEN/AKT/mTOR pathway
Published in Cell death & disease (05-01-2018)“…Epithelial cell adhesion molecule (EpCAM) is known to be highly expressed in a variety of epithelial carcinomas, and it is involved in cell adhesion and…”
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miR-665 expression predicts poor survival and promotes tumor metastasis by targeting NR4A3 in breast cancer
Published in Cell death & disease (17-06-2019)“…Cancer metastasis is the main cause of death in breast cancer (BC) patients. Therefore, prediction and treatment of metastasis is critical for enhancing the…”
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Phosphorylation of androgen receptor by mTORC1 promotes liver steatosis and tumorigenesis
Published in Hepatology (Baltimore, Md.) (01-05-2022)“…Background and Aims Androgen receptor (AR) has been reported to play an important role in the development and progression of man’s prostate cancer…”
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Identification of two microRNA signatures in whole blood as novel biomarkers for diagnosis of nasopharyngeal carcinoma
Published in Journal of translational medicine (03-06-2019)“…Early diagnosis is critical to reduce the mortality caused by nasopharyngeal carcinoma (NPC). MicroRNAs (miRNAs) are dysregulated and play important roles in…”
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Lnc-GAN1 expression is associated with good survival and suppresses tumor progression by sponging mir-26a-5p to activate PTEN signaling in non-small cell lung cancer
Published in Journal of experimental & clinical cancer research (06-01-2021)“…Long non-coding RNAs (lncRNAs) play vital roles in the development and progression of non-small-cell lung cancer (NSCLC); however, the role of most lncRNAs in…”
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ULK1: a promising biomarker in predicting poor prognosis and therapeutic response in human nasopharygeal carcinoma
Published in PloS one (25-02-2015)“…Plenty of studies have established that dysregulation of autophagy plays an essential role in cancer progression. The autophagy-related proteins have been…”
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Upregulated TRIM29 promotes proliferation and metastasis of nasopharyngeal carcinoma via PTEN/AKT/mTOR signal pathway
Published in Oncotarget (22-03-2016)“…Tripartite motif-containing 29 (TRIM29) has been reported to be dysregulated in human cancers. Up-regulation of TRIM29 was first observed in NPC cell lines by…”
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Overexpression of YAP 1 contributes to progressive features and poor prognosis of human urothelial carcinoma of the bladder
Published in BMC cancer (19-07-2013)“…Yes-associated protein 1 (YAP 1), the nuclear effector of the Hippo pathway, is a key regulator of organ size and a candidate human oncogene in multiple…”
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Identification of a 4-lncRNA signature predicting prognosis of patients with non-small cell lung cancer: a multicenter study in China
Published in Journal of translational medicine (20-08-2020)“…Previous findings have indicated that the tumor, nodes, and metastases (TNM) staging system is not sufficient to accurately predict survival outcomes in…”
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Combination Treatment With Inhibitors of ERK and Autophagy Enhances Antitumor Activity of Betulinic Acid in Non–small-Cell Lung Cancer In Vivo and In Vitro
Published in Frontiers in pharmacology (29-06-2021)“…Aberrant activation of the Ras–ERK signaling pathway drives many important cancer phenotypes, and several inhibitors targeting such pathways are under…”
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LncRNA CSMD1-1 promotes the progression of Hepatocellular Carcinoma by activating MYC signaling
Published in Theranostics (01-01-2020)“…Emerging evidence suggests that long non-coding RNAs (lncRNA) play critical roles in the development and progression of diverse cancers including…”
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MicroRNA-29c enhances the sensitivities of human nasopharyngeal carcinoma to cisplatin-based chemotherapy and radiotherapy
Published in Cancer letters (01-02-2013)“…Highlights ► MiR-29c downregulation in tumor is closely associated with a poor therapeutic response in NPC patients. ► MiR-29c overexpression could sensitize…”
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CLDN14 is epigenetically silenced by EZH2-mediated H3K27ME3 and is a novel prognostic biomarker in hepatocellular carcinoma
Published in Carcinogenesis (New York) (01-06-2016)“…Trimethylation of lysine 27 on histone H3 (H3K27ME3) is a transcription-suppressive histone mark mediated by enhancer of zeste homolog 2 (EZH2). We have…”
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The prognostic value of a seven-lncRNA signature in patients with esophageal squamous cell carcinoma: a lncRNA expression analysis
Published in Journal of translational medicine (31-01-2020)“…Long non-coding RNAs (lncRNAs) have been reported to be prognostic biomarkers in many types of cancer. We aimed to identify a lncRNA signature that can predict…”
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BMP2 promotes proliferation and invasion of nasopharyngeal carcinoma cells via mTORC1 pathway
Published in Aging (Albany, NY.) (28-04-2017)“…Bone morphogenetic protein-2 (BMP2) is a secreted protein that highly expressed in a variety of cancers and contributes to cell proliferation, migration,…”
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Two somatic mutations in the androgen receptor N-terminal domain are oncogenic drivers in hepatocellular carcinoma
Published in Communications biology (05-01-2024)“…The androgen receptor ( AR ) plays an important role in male-dominant hepatocellular carcinoma, and specific acquired somatic mutations of AR have been…”
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The telomere/telomerase binding factor PinX1 is a new target to improve the radiotherapy effect of oesophageal squamous cell carcinomas
Published in The Journal of pathology (01-04-2013)“…Chemoradiotherapy (CRT) is a standard treatment for oesophageal squamous cell carcinoma (ESCC) in its advanced stages. The telomerase/telomere interacting…”
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Overexpression of the secretory small GTPase Rab27B in human breast cancer correlates closely with lymph node metastasis and predicts poor prognosis
Published in Journal of translational medicine (05-12-2012)“…The secretory small GTPase Rab27b was recently identified as an oncogene in breast cancer (BC) in vivo and in vitro studies. This research was designed to…”
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Evaluation of serum clusterin as a surveillance tool for human hepatocellular carcinoma with hepatitis B virus related cirrhosis
Published in Journal of gastroenterology and hepatology (01-06-2010)“…Background and Aim: Hepatocellular carcinoma (HCC) is a common human cancer worldwide. The levels of serum clusterin in HCC patients and its potential…”
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Cell cycle‐related kinase supports ovarian carcinoma cell proliferation via regulation of cyclin D1 and is a predictor of outcome in patients with ovarian carcinoma
Published in International journal of cancer (01-12-2009)“…Our previous study has suggested that the cell cycle‐related kinase (CCRK) is a putative candidate oncogene in glioblastoma tumorigenesis. The potential…”
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