Search Results - "Mai, Quynh N."

The organic cation transporter 2 regulates dopamine D1 receptor signaling at the Golgi apparatus by Puri, Natasha M, Romano, Giovanna R, Lin, Ting-Yu, Mai, Quynh N, Irannejad, Roshanak

“…Dopamine is a key catecholamine in the brain and kidney, where it is involved in a number of physiological functions such as locomotion, cognition, emotion,…”
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Cardiac contraction and relaxation are regulated by distinct subcellular cAMP pools by Lin, Ting-Yu, Mai, Quynh N., Zhang, Hao, Wilson, Emily, Chien, Huan-Chieh, Yee, Sook Wah, Giacomini, Kathleen M., Olgin, Jeffrey E., Irannejad, Roshanak

“…Cells interpret a variety of signals through G-protein-coupled receptors (GPCRs) and stimulate the generation of second messengers such as cyclic adenosine…”
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A pH-responsive nanoparticle targets the neurokinin 1 receptor in endosomes to prevent chronic pain by Ramírez-García, Paulina D., Retamal, Jeffri S., Shenoy, Priyank, Imlach, Wendy, Sykes, Matthew, Truong, Nghia, Constandil, Luis, Pelissier, Teresa, Nowell, Cameron J., Khor, Song Y., Layani, Louis M., Lumb, Chris, Poole, Daniel P., Lieu, TinaMarie, Stewart, Gregory D., Mai, Quynh N., Jensen, Dane D., Latorre, Rocco, Scheff, Nicole N., Schmidt, Brian L., Quinn, John F., Whittaker, Michael R., Veldhuis, Nicholas A., Davis, Thomas P., Bunnett, Nigel W.

“…Nanoparticle-mediated drug delivery is especially useful for targets within endosomes because of the endosomal transport mechanisms of many nanomedicines…”
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Neurokinin 1 receptor signaling in endosomes mediates sustained nociception and is a viable therapeutic target for prolonged pain relief by Jensen, Dane D, Lieu, TinaMarie, Halls, Michelle L, Veldhuis, Nicholas A, Imlach, Wendy L, Mai, Quynh N, Poole, Daniel P, Quach, Tim, Aurelio, Luigi, Conner, Joshua, Herenbrink, Carmen Klein, Barlow, Nicholas, Simpson, Jamie S, Scanlon, Martin J, Graham, Bimbil, McCluskey, Adam, Robinson, Phillip J, Escriou, Virginie, Nassini, Romina, Materazzi, Serena, Geppetti, Pierangelo, Hicks, Gareth A, Christie, Macdonald J, Porter, Christopher J H, Canals, Meritxell, Bunnett, Nigel W

“…Typically considered to be cell surface sensors of extracellular signals, heterotrimeric GTP-binding protein (G protein)-coupled receptors (GPCRs) control many…”
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A lipid-anchored neurokinin 1 receptor antagonist prolongs pain relief by a three-pronged mechanism of action targeting the receptor at the plasma membrane and in endosomes by Mai, Quynh N., Shenoy, Priyank, Quach, Tim, Retamal, Jeffri S., Gondin, Arisbel B., Yeatman, Holly R., Aurelio, Luigi, Conner, Joshua W., Poole, Daniel P., Canals, Meritxell, Nowell, Cameron J., Graham, Bim, Davis, Thomas P., Briddon, Stephen J., Hill, Stephen J., Porter, Christopher J.H., Bunnett, Nigel W., Halls, Michelle L., Veldhuis, Nicholas A.

“…G-protein-coupled receptors (GPCRs) are traditionally known for signaling at the plasma membrane, but they can also signal from endosomes after internalization…”
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Improving Cellular Uptake and Endosomal Targeting of Neurokinin 1 Receptor Antagonists by Veldhuis, Nicholas A, Mai, Quynh N, Conner, Josh N, Graham, Bim, Halls, Michelle, Lieu, TinaMarie, Bunnett, Nigel W

“…Abstract only Intro G protein‐coupled receptors (GPCRs) are cell‐surface sensors that control most pathophysiological processes. Following stimulation, many…”
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Intracellular drug delivery : a route to more selective and effective treatments for disease by Mai, Quynh N

“…The Neurokinin 1 receptor (NK1R) is a G protein-coupled receptor (GPCR) and member of the tachykinin family expressed in the central nervous system, immune…”
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Uncovering new regulators of Arabidopsis thaliana fruit morphogenesis by Mai, Quynh-Anh N

“…The story of the network of genes that controls fruit patterning in Arabidopsis is still unfolding, and here we have seen familiar players take on different…”
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