Search Results - "Mai, Jia"
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FUT8-mediated aberrant N-glycosylation of B7H3 suppresses the immune response in triple-negative breast cancer
Published in Nature communications (11-05-2021)“…Most patients with triple negative breast cancer (TNBC) do not respond to anti-PD1/PDL1 immunotherapy, indicating the necessity to explore immune checkpoint…”
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Journal Article -
2
Autophagy deficiency promotes triple-negative breast cancer resistance to T cell-mediated cytotoxicity by blocking tenascin-C degradation
Published in Nature communications (30-07-2020)“…Most triple-negative breast cancer (TNBC) patients fail to respond to T cell-mediated immunotherapies. Unfortunately, the molecular determinants are still…”
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3
YAP in pancreatic cancer: oncogenic role and therapeutic strategy
Published in Theranostics (2021)“…Pancreatic cancer, especially pancreatic ductal adenocarcinoma (PDAC), remains a fatal disease with few efficacious treatments. The Hippo signaling pathway, an…”
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Journal Article Book Review -
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Rapid and Reliable Detection of Alkaline Phosphatase by a Hot Spots Amplification Strategy Based on Well-Controlled Assembly on Single Nanoparticle
Published in ACS applied materials & interfaces (06-09-2017)“…The first appeal of clinical assay is always accurate and rapid. For alkaline phosphatase (ALP) monitoring in medical treatment, a rapid, reliable…”
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5
The role of macrophage and adipocyte mitochondrial dysfunction in the pathogenesis of obesity
Published in Frontiers in immunology (08-11-2024)“…Obesity has emerged as a prominent global public health concern, leading to the development of numerous metabolic disorders such as cardiovascular diseases,…”
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6
Autophagy-mediated negative feedback attenuates the oncogenic activity of YAP in pancreatic cancer
Published in International journal of biological sciences (01-01-2021)“…Pancreatic ductal adenocarcinoma (PDAC) is the most lethal malignancy in humans, and new therapeutic targets are urgently needed. Yes-associated protein (YAP)…”
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7
cKit⁺ cardiac progenitors of neural crest origin
Published in Proceedings of the National Academy of Sciences - PNAS (20-10-2015)“…The degree to whichcKit-expressing progenitors generate cardiomyocytes in the heart is controversial. Genetic fate-mapping studies suggest minimal…”
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Regorafenib Promotes Antitumor Immunity via Inhibiting PD-L1 and IDO1 Expression in Melanoma
Published in Clinical cancer research (15-07-2019)“…Immune checkpoint blockade (ICB) therapy induces durable tumor regressions in a minority of patients with cancer. In this study, we aimed to identify kinase…”
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Activation of CB1R alleviates central sensitization by regulating HCN2-pNR2B signaling in a chronic migraine rat model
Published in Journal of headache and pain (21-04-2023)“…Background Central sensitization has been widely accepted as an underlying pathophysiological mechanism of chronic migraine (CM), activation of cannabinoid…”
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The nexus of dynamic T cell states and immune checkpoint blockade therapy in the periphery and tumor microenvironment
Published in Frontiers in immunology (10-10-2023)“…Immune checkpoint blockade (ICB) therapies, that is, using monoclonal antibodies to reinvigorate tumor-reactive, antigen-specific T cells from the inhibitory…”
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11
Cocaine reward and memory after chemogenetic inhibition of distinct serotonin neuron subtypes in mice
Published in Psychopharmacology (01-09-2020)“…Rationale We probed serotonin neurons, those denoted by their developmental gene expression as r2Hoxa2-Pet1 (experiment 1) and Drd1a-Pet1 (experiment 2), for…”
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Fis1 phosphorylation by Met promotes mitochondrial fission and hepatocellular carcinoma metastasis
Published in Signal transduction and targeted therapy (01-12-2021)“…Met tyrosine kinase, a receptor for a hepatocyte growth factor (HGF), plays a critical role in tumor growth, metastasis, and drug resistance. Mitochondria are…”
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Corrigendum: Therapeutic strategies targeting folate receptor α for ovarian cancer
Published in Frontiers in immunology (17-04-2024)“…[This corrects the article DOI: 10.3389/fimmu.2023.1254532.]…”
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Occurrence and Transmission of blaNDM-Carrying Enterobacteriaceae from Geese and the Surrounding Environment on a Commercial Goose Farm
Published in Applied and environmental microbiology (01-05-2021)“…We investigated the prevalence and transmission of NDM-producing Enterobacteriaceae in fecal samples of geese and environmental samples from a goose farm in…”
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Disruption of super-enhancer-driven tumor suppressor gene RCAN1.4 expression promotes the malignancy of breast carcinoma
Published in Molecular cancer (08-08-2020)“…Abstract Background Super-enhancers (SEs) play a crucial role in cancer, which is often associate with activated oncogenes. However, little is known about how…”
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CaMKII-mediated Beclin 1 phosphorylation regulates autophagy that promotes degradation of Id and neuroblastoma cell differentiation
Published in Nature communications (27-10-2017)“…Autophagy is a degradative pathway that delivers cellular components to the lysosome for degradation. The role of autophagy in cell differentiation is poorly…”
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The Characteristics of the Nursing Organizational Management Highlighted by COVID-19
Published in E3S Web of Conferences (01-01-2021)“…The COVID-19 outbreak has raised awareness of the importance of increased motivation and resilience in nurses. To explore the level of nurse Job involvement in…”
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Journal Article Conference Proceeding -
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Therapeutic strategies targeting folate receptor α for ovarian cancer
Published in Frontiers in immunology (2023)“…Epithelial ovarian cancer (EOC) is the deadliest gynecological cancer, and presents a major clinical challenge due to limited treatment options. Folate…”
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Systematic analysis of expression profiles and prognostic significance for MMDS-related iron–sulfur proteins in renal clear cell carcinoma
Published in Scientific reports (16-11-2022)“…Mitochondrial metabolism disorders play an important role in the occurrence and development of tumors, and iron–sulfur protein is an important molecule for…”
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AKT-mediated regulation of chromatin ubiquitylation and tumorigenesis through Mel18 phosphorylation
Published in Oncogene (01-04-2021)“…Polycomb repressor complex 1 (PRC1) is linked to the regulation of gene expression and histone ubiquitylation conformation, which contributes to…”
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