Search Results - "Mahy, Pierre"
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Enzyme Encapsulation in Mesoporous Metal–Organic Frameworks for Selective Biodegradation of Harmful Dye Molecules
Published in Angewandte Chemie International Edition (03-12-2018)“…Microperoxidase‐8, a small, peroxidase‐type enzyme was immobilized into nanoparticles of the mesoporous and ultra‐stable metal–organic framework (MOF)…”
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Encapsulation of Microperoxidase‐8 into MIL‐101(Cr/Fe) Nanoparticles: A New Biocatalyst for the Epoxidation of Styrene
Published in European journal of inorganic chemistry (03-07-2023)“…A new biocatalyst MP8@MIL‐101(Cr/Fe) was prepared by immobilization of a heme octapeptide, Microperoxidase 8 (MP8) within a mixed metal MOF, MIL‐101(Cr/Fe)…”
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3
Artificial Enzymes for Diels‐Alder Reactions
Published in Chembiochem : a European journal of chemical biology (02-02-2021)“…The Diels‐Alder (DA) reaction is a cycloaddition of a conjugated diene and an alkene (dienophile) leading to the formation of a cyclohexene derivative through…”
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Receptor-Based Artificial Metalloenzymes on Living Human Cells
Published in Journal of the American Chemical Society (18-07-2018)“…Artificial metalloenzymes are known to be promising tools for biocatalysis, but their recent compartmentalization has led to compatibly with cell components…”
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Detoxification of V‐Nerve Agents Assisted by a Microperoxidase: New Pathway Revealed by the Use of a Relevant VX Simulant
Published in Chembiochem : a European journal of chemical biology (01-08-2024)“…The biocatalyzed oxidative detoxification of the V‐series simulant PhX, by mean of the microperoxidase AcMP11, affords the corresponding phosphonothioate as…”
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Binding and Stabilization of a Semiquinone Radical by an Artificial Metalloenzyme Containing a Binuclear Copper (II) Cofactor
Published in Chembiochem : a European journal of chemical biology (01-10-2024)“…A binuclear Cu(II) cofactor was covalently bound to a lauric acid anchor. The resulting conjugate was characterized then combined with beta‐lactoglobulin (βLG)…”
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An Artificial Hemoprotein with Inducible Peroxidase‐ and Monooxygenase‐Like Activities
Published in Chemistry : a European journal (20-11-2020)“…A novel inducible artificial metalloenzyme obtained by covalent attachment of a manganese(III)‐tetraphenylporphyrin (MnTPP) to the artificial bidomain repeat…”
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Aerobic Baeyer–Villiger Oxidation Catalyzed by a Flavin‐Containing Enzyme Mimic in Water
Published in Angewandte Chemie International Edition (10-12-2018)“…Direct incorporation of molecular oxygen into small organic molecules has attracted much attention for the development of new environmentally friendly…”
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Catalytic CH Amination: A Reaction Now Accessible to Engineered Natural Enzymes
Published in Angewandte Chemie International Edition (01-07-2014)“…Catalytic CH aminations with natural enzymes have not been reported thus far. However, when a cytochrome P450 enzyme is modified by switching from an…”
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Photocatalytic Hydrogen Production and Carbon Dioxide Reduction Catalyzed by an Artificial Cobalt Hemoprotein
Published in International journal of molecular sciences (01-12-2022)“…The covalent insertion of a cobalt heme into the cavity of an artificial protein named alpha Rep (αRep) leads to an artificial cobalt hemoprotein that is…”
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11
Photoassisted Generation of a Dinuclear Iron(III) Peroxo Species and Oxygen-Atom Transfer
Published in Angewandte Chemie International Edition (25-03-2013)“…Closing the loop: Light absorption by a sensitizer–diiron(III) complex in the presence of a sacrificial electron donor and subsequent exposure to O2 led to the…”
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Artificial iron hydrogenase made by covalent grafting of Knölker's complex into xylanase: Application in asymmetric hydrogenation of an aryl ketone in water
Published in Biotechnology and applied biochemistry (01-07-2020)“…We report a new artificial hydrogenase made by covalent anchoring of the iron Knölker's complex to a xylanase S212C variant. This artificial metalloenzyme was…”
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13
αRep A3: A Versatile Artificial Scaffold for Metalloenzyme Design
Published in Chemistry : a European journal (26-07-2017)“…αRep refers to a new family of artificial proteins based on a thermostable α‐helical repeated motif. One of its members, αRep A3, forms a stable homo‐dimer…”
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Artificial Metalloenzymes with the Neocarzinostatin Scaffold: Toward a Biocatalyst for the Diels-Alder Reaction
Published in Chembiochem : a European journal of chemical biology (02-03-2016)“…A copper(II) cofactor coupled to a testosterone anchor, copper(II)‐(5‐(Piperazin‐1‐yl)‐1,10‐phenanthroline)testosterone‐17‐hemisuccinamide (10) was synthesized…”
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CuII‐Containing 1‐Aminocyclopropane Carboxylic Acid Oxidase Is an Efficient Stereospecific Diels–Alderase
Published in Angewandte Chemie International Edition (07-10-2019)“…In the context of developing ecofriendly chemistry, artificial enzymes are now considered as promising tools for synthesis. They are prepared in particular…”
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Imidazolidine Ring Cleavage upon Complexation with First‐Row Transition Metals
Published in European journal of inorganic chemistry (08-09-2017)“…The reaction of a cyclic diaminal ligand, obtained from the reaction of N,N′‐bis(2‐pyridylmethyl)ethane‐1,2‐diamine, as a secondary diamine, and…”
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Neocarzinostatin-based hybrid biocatalysts for oxidation reactions
Published in Dalton transactions : an international journal of inorganic chemistry (14-06-2014)“…An anionic iron(III)-porphyrin-testosterone conjugate 1-Fe has been synthesized and fully characterized. It has been further associated with a neocarzinostatin…”
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Selective Formation of an FeIVO or an FeIIIOOH Intermediate From Iron(II) and H2O2: Controlled Heterolytic versus Homolytic Oxygen–Oxygen Bond Cleavage by the Second Coordination Sphere
Published in Angewandte Chemie International Edition (01-01-2019)“…We demonstrate that the devised incorporation of an alkylamine group into the second coordination sphere of an FeII complex allows to switch its reactivity…”
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Recent progress in the development of new artificial metalloenzymes as biocatalysts for selective oxidations and Diels‐Alder reaction ‐ Mini‐Review
Published in Vietnam journal of chemistry (01-08-2020)“…Our recent research is turning towards the elaboration of artificial metalloenzymes that catalyze reactions of interest for organic chemistry under…”
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Incorporation of Manganese Complexes into Xylanase: New Artificial Metalloenzymes for Enantioselective Epoxidation
Published in Chembiochem : a European journal of chemical biology (23-01-2012)“…Here we report the best artificial metalloenzyme to date for the selective oxidation of aromatic alkenes; it was obtained by noncovalent insertion of…”
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